Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture.

[1]  Michael Q. Zhang,et al.  Combinatorial patterns of histone acetylations and methylations in the human genome , 2008, Nature Genetics.

[2]  H. Kirchner,et al.  In vitro proliferation and differentiation of human CD34+ cells from peripheral blood into mature red blood cells with two different cell culture systems , 2008, Transfusion.

[3]  T. Takayama,et al.  Ex vivo large-scale generation of human red blood cells from cord blood CD34+ cells by co-culturing with macrophages , 2008, International journal of hematology.

[4]  E. Bouhassira,et al.  Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells produced from human embryonic stem cells. , 2008, Blood.

[5]  I. Dunham,et al.  Tissue-specific histone modification and transcription factor binding in alpha globin gene expression. , 2007, Blood.

[6]  F. Recillas-Targa,et al.  GATA-1 Modulates the Chromatin Structure and Activity of the Chicken α-Globin 3′ Enhancer , 2007, Molecular and Cellular Biology.

[7]  M. Mahajan,et al.  Control of beta globin genes , 2007, Journal of cellular biochemistry.

[8]  J. Lingrel,et al.  EKLF and KLF2 have compensatory roles in embryonic β-globin gene expression and primitive erythropoiesis , 2007 .

[9]  G. Felsenfeld,et al.  We gather together: insulators and genome organization. , 2007, Current opinion in genetics & development.

[10]  Ruedi Aebersold,et al.  Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus. , 2007, Molecular cell.

[11]  R. Young,et al.  A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells , 2007, Cell.

[12]  M. Furlan-Magaril,et al.  Globin genes transcriptional switching, chromatin structure and linked lessons to epigenetics in cancer: a comparative overview. , 2007, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

[13]  Yijun Ruan,et al.  Mapping of transcription factor binding regions in mammalian cells by ChIP: comparison of array- and sequencing-based technologies. , 2007, Genome research.

[14]  G. Blobel,et al.  Dissecting Molecular Steps in Chromatin Domain Activation during Hematopoietic Differentiation , 2007, Molecular and Cellular Biology.

[15]  Nathaniel D. Heintzman,et al.  Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome , 2007, Nature Genetics.

[16]  Douglas R Higgs,et al.  Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression. , 2007, The EMBO journal.

[17]  J. Lingrel,et al.  EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis. , 2007, Blood.

[18]  M. Vigneron,et al.  CTCF Interacts with and Recruits the Largest Subunit of RNA Polymerase II to CTCF Target Sites Genome-Wide , 2007, Molecular and Cellular Biology.

[19]  L. Verdone,et al.  Histone acetylation in gene regulation. , 2006, Briefings in functional genomics & proteomics.

[20]  D. Higgs,et al.  A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element. , 2006, Blood.

[21]  Yoshihide Hayashizaki,et al.  Histone H3 acetylated at lysine 9 in promoter is associated with low nucleosome density in the vicinity of transcription start site in human cell , 2006, Chromosome Research.

[22]  P. Kingsley,et al.  "Maturational" globin switching in primary primitive erythroid cells. , 2005, Blood.

[23]  M. Cam,et al.  A newly discovered human alpha-globin gene. , 2005, Blood.

[24]  G. Blobel,et al.  Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. , 2005, Molecular cell.

[25]  G. Stamatoyannopoulos.  Control of globin gene expression during development and erythroid differentiation. , 2005, Experimental hematology.

[26]  Keji Zhao,et al.  Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. , 2005, Genes & development.

[27]  Laurent Kiger,et al.  Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells , 2005, Nature Biotechnology.

[28]  G. Stamatoyannopoulos,et al.  Histone acetylation at the human β-globin locus changes with developmental age , 2004 .

[29]  G. Stamatoyannopoulos,et al.  Transcriptional potentials of the beta-like globin genes at different developmental stages in transgenic mice and hemoglobin switching. , 2004, Blood cells, molecules & diseases.

[30]  G. Blobel,et al.  Globin gene activation during haemopoiesis is driven by protein complexes nucleated by GATA‐1 and GATA‐2 , 2004, The EMBO journal.

[31]  T. Jenuwein,et al.  An epigenetic road map for histone lysine methylation , 2003, Journal of Cell Science.

[32]  Jessica Halow,et al.  The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation. , 2003, Genes & development.

[33]  R. Kiyama,et al.  Interaction of NF-E2 in the Human β-Globin Locus Control Region before Chromatin Remodeling* , 2003, The Journal of Biological Chemistry.

[34]  J. Hughes,et al.  De novo deletion within the telomeric region flanking the human α globin locus as a cause of α thalassaemia , 2003, British journal of haematology.

[35]  Xiangdong Fang,et al.  Locus control regions. , 2002, Blood.

[36]  Henri Wajcman,et al.  Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo , 2002, Nature Biotechnology.

[37]  Jeffery L. Miller,et al.  Fetal and adult hemoglobin production during adult erythropoiesis: coordinate expression correlates with cell proliferation. , 2002, Blood.

[38]  David J States,et al.  Faculty Opinions recommendation of GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis. , 2002 .

[39]  M. Gerstein,et al.  GATA-1 binding sites mapped in the β-globin locus by using mammalian chIp-chip analysis , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[40]  M. Groudine,et al.  Activation of β-major globin gene transcription is associated with recruitment of NF-E2 to the β-globin LCR and gene promoter , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[41]  R. Kiyama,et al.  Enhancer activity of HS2 of the human beta-LCR is modulated by distance from the key nucleosome. , 2001, Nucleic acids research.

[42]  Kirby D. Johnson,et al.  Distinct mechanisms control RNA polymerase II recruitment to a tissue-specific locus control region and a downstream promoter. , 2001, Molecular cell.

[43]  E. Bresnick,et al.  Direct interaction of NF-E2 with hypersensitive site 2 of the beta-globin locus control region in living cells. , 2000, Blood.

[44]  C. Peschle,et al.  Hemoglobin switching in unicellular erythroid culture of sibling erythroid burst-forming units: kit ligand induces a dose-dependent fetal hemoglobin reactivation potentiated by sodium butyrate. , 2000, Blood.

[45]  K. Chin,et al.  Two‐phase liquid culture system models normal human adult erythropoiesis at the molecular level , 2000, European journal of haematology.

[46]  G. Stamatoyannopoulos,et al.  Analysis of enhancer function of the HS-40 core sequence of the human alpha-globin cluster. , 1997, Nucleic acids research.

[47]  D. Tenen,et al.  Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[48]  G. Condorelli,et al.  Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis. , 1995, The Journal of clinical investigation.

[49]  A. Carè,et al.  Developmental switching of messenger RNA expression from the human alpha-globin cluster: fetal/adult pattern of theta-globin gene expression. , 1992, Blood.

[50]  A. Jarman,et al.  Characterization of the major regulatory element upstream of the human alpha-globin gene cluster , 1991, Molecular and cellular biology.

[51]  T. Ley,et al.  Globin gene expression in erythroid human fetal liver cells. , 1989, The Journal of clinical investigation.

[52]  L. Douay,et al.  Ex vivo generation of human red blood cells: a new advance in stem cell engineering. , 2009, Methods in molecular biology.

[53]  D. Higgs,et al.  Long-range regulation of alpha-globin gene expression. , 2008, Advances in genetics.

[54]  G. Filippova.  Genetics and epigenetics of the multifunctional protein CTCF. , 2008, Current topics in developmental biology.

[55]  F. Recillas-Targa,et al.  GATA-1 modulates the chromatin structure and activity of the chicken alpha-globin 3' enhancer. , 2008, Molecular and cellular biology.

[56]  L. Di,et al.  HS-48 alone has no enhancement role on the expression of human α-globin gene cluster , 2007 .

[57]  L. Di,et al.  HS-48 alone has no enhancement role on the expression of human alpha-globin gene cluster. , 2007, Blood cells, molecules & diseases.

[58]  G. Stamatoyannopoulos,et al.  Histone acetylation at the human beta-globin locus changes with developmental age. , 2007, Blood.

[59]  A. Migliaccio,et al.  In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients. , 2002, Blood cells, molecules & diseases.

[60]  D. Higgs,et al.  Targeted inactivation of the major positive regulatory element (HS-40) of the human alpha-globin gene locus. , 1995, Blood.

[61]  D. Housman,et al.  Hemoglobin synthesis in human BFU-E and CFU-E-derived erythroid colonies. , 1979, Blood.