The significance of tumor persistence after incomplete excision of basal cell carcinoma.

BACKGROUND Physicians inevitably receive a pathology report after excision of a basal cell carcinoma that indicates that it is incompletely excised. The physician and patient are then left with the dilemma of whether immediate re-excision or close clinical follow-up is indicated. OBJECTIVE Our purpose was to identify characteristics of incompletely excised basal cell carcinomas that are at low risk for recurrence. METHODS We retrospectively reviewed the charts and pathology slides of all incompletely excised basal cell carcinomas from 1991 to 1994 in a university hospital tumor registry. RESULTS Incompletely excised basal cell carcinomas of superficial or nodular subtype, less than 1 cm in diameter, located anywhere except the nose or ears, with less than 4% marginal involvement on the initial inadequate excision had no evidence of tumor persistence. CONCLUSION When physicians receive a pathology report indicating the incomplete excision of a basal cell carcinoma, they face the dilemma of further management. The majority of patients should undergo immediate re-excision or Mohs micrographic surgery because tumor persistence was found in 28% of cases. Occasionally, for a small group of select patients, close clinical follow-up may be indicated if the risk of recurrence is very low.

[1]  H. Friedman,et al.  Recurrent basal cell carcinoma in margin-positive tumors. , 1997, Annals of plastic surgery.

[2]  H. W. Randle Basal Cell Carcinoma Identification and Treatment of the High‐Risk Patient , 1996, Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.].

[3]  M A Weinstock,et al.  Nonmelanoma skin cancer in the United States: incidence. , 1994, Journal of the American Academy of Dermatology.

[4]  R. Kirsner,et al.  The use of Mohs micrographic surgery for determination of residual tumor in incompletely excised basal cell carcinoma. , 1992, Journal of the American Academy of Dermatology.

[5]  T. Tong,et al.  Cancer statistics, 1991 , 1991, CA: a cancer journal for clinicians.

[6]  F. Mohs,et al.  Metastatic basal cell carcinoma: report of twelve cases with a review of the literature. , 1991, Journal of the American Academy of Dermatology.

[7]  R. Carroll,et al.  Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up. , 1989, The Journal of dermatologic surgery and oncology.

[8]  A. Dellon,et al.  Recurrence rate of positive margin basal cell carcinoma: results of a five-year prospective study. , 1985 .

[9]  D. Sarma,et al.  Observations on the inadequately excised basal cell carcinomas , 1984, Journal of surgical oncology.

[10]  H. Zarem RECURRENT BASAL CELL CARCINOMA , 1981 .

[11]  H. Zarem,et al.  Recurrent basal cell carcinoma. A review concerning the incidence, behavior, and management of recurrent basal cell carcinoma, with emphasis on the incompletely excised lesion. , 1980, Plastic and reconstructive surgery.

[12]  R. Pascal,et al.  PROGNOSIS OF “INCOMPLETELY EXCISED” VERSUS “COMPLETELY EXCISED” BASAL CELL CARCINOMA , 1968, Plastic and reconstructive surgery.

[13]  C. Gooding,et al.  Significance of marginal extension in excised basal-cell carcinoma. , 1965, The New England journal of medicine.