Quantitative Profiling of Human Renal UDP-glucuronosyltransferases and Glucuronidation Activity: A Comparison of Normal and Tumoral Kidney Tissues
暂无分享,去创建一个
C. Guillemette | Philip C. Smith | G. Margaillan | M. Rouleau | J. K. Fallon | P. Caron | L. Villeneuve | V. Turcotte | P. C. Smith | M. S. Joy | C. Guillemette | J. K. Fallon | M. Rouleau | P. Caron | M. Joy | L. Villeneuve | V. Turcotte | G. Margaillan | Guillaume Margaillan | Guillaume Margaillan
[1] M. Manns,et al. Differential down-regulation of the UDP-glucuronosyltransferase 1A locus is an early event in human liver and biliary cancer. , 1997, Cancer research.
[2] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[3] R. Dellinger,et al. Anti-Cancer Drugs Elicit Re-Expression of UDP-Glucuronosyltransferases in Melanoma Cells , 2012, PloS one.
[4] B. Burchell,et al. The expression of UDP-glucuronosyltransferases of the UGT1 family in human liver and kidney and in response to drugs. , 1993, Biochemical pharmacology.
[5] F. Oesch,et al. Extrahepatic metabolism at the body's internal–external interfaces , 2014, Drug metabolism reviews.
[6] C. Guillemette,et al. Overexpression of uridine diphospho glucuronosyltransferase 2B17 in high-risk chronic lymphocytic leukemia. , 2013, Blood.
[7] Apurva A Desai,et al. Sorafenib in advanced clear-cell renal-cell carcinoma. , 2007, The New England journal of medicine.
[8] Jian Shi,et al. Significantly Decreased and More Variable Expression of Major CYPs and UGTs in Liver Microsomes Prepared from HBV-Positive Human Hepatocellular Carcinoma and Matched Pericarcinomatous Tissues Determined Using an Isotope Label-free UPLC-MS/MS Method , 2014, Pharmaceutical Research.
[9] Michèle Rouleau,et al. Pharmacogenomics of Human Uridine Diphospho‐Glucuronosyltransferases and Clinical Implications , 2014, Clinical pharmacology and therapeutics.
[10] C. Guillemette,et al. Circulating estrogens in endometrial cancer cases and their relationship with tissular expression of key estrogen biosynthesis and metabolic pathways. , 2010, The Journal of clinical endocrinology and metabolism.
[11] C. Guillemette,et al. Glucuronidation of the Antiretroviral Drug Efavirenz by UGT2B7 and an in Vitro Investigation of Drug-Drug Interaction with Zidovudine , 2009, Drug Metabolism and Disposition.
[12] Hendrik Neubert,et al. Targeted Precise Quantification of 12 Human Recombinant Uridine-Diphosphate Glucuronosyl Transferase 1A and 2B Isoforms Using Nano-Ultra-High-Performance Liquid Chromatography/Tandem Mass Spectrometry with Selected Reaction Monitoring , 2013, Drug Metabolism and Disposition.
[13] K. Knights,et al. Renal drug metabolism in humans: the potential for drug–endobiotic interactions involving cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT) , 2013, British journal of clinical pharmacology.
[14] Armando Santoro,et al. Sorafenib: a review of its use in advanced hepatocellular carcinoma. , 2009, Drugs.
[15] B. Leber,et al. The sonic hedgehog factor Gli1 imparts drug resistance through inducible glucuronidation , 2014, Nature.
[16] V. Zagonel,et al. Clinical experience and critical evaluation of the role of sorafenib in renal cell carcinoma , 2011, Open access journal of urology.
[17] Shuji Ohno,et al. Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction , 2009, Drug Metabolism and Disposition.
[18] Akio Kawamura,et al. Protein quantification of UDP-glucuronosyltransferases 1A1 and 2B7 in human liver microsomes by LC-MS/MS and correlation with glucuronidation activities , 2012, Xenobiotica; the fate of foreign compounds in biological systems.
[19] R. Fujiwara,et al. Expression of UGT1A and UGT2B mRNA in Human Normal Tissues and Various Cell Lines , 2008, Drug Metabolism and Disposition.
[20] B. Burchell,et al. Drug glucuronidation by human renal UDP-glucuronosyltransferases. , 1998, Biochemical pharmacology.
[21] M. W. Anders. Metabolism of drugs by the kidney. , 1980, Kidney international.
[22] M. Nagata,et al. Optimized Methods for Targeted Peptide-Based Quantification of Human Uridine 5′-Diphosphate-Glucuronosyltransferases in Biological Specimens Using Liquid Chromatography–Tandem Mass Spectrometry , 2014, Drug Metabolism and Disposition.
[23] C. Guillemette,et al. Immunohistochemical expression of conjugating UGT1A‐derived isoforms in normal and tumoral drug‐metabolizing tissues in humans , 2011, The Journal of pathology.
[24] K. Knights,et al. Renal UDP-glucuronosyltransferases and the glucuronidation of xenobiotics and endogenous mediators , 2010, Drug metabolism reviews.
[25] A. Starlard-Davenport,et al. Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene , 2008, Steroids.
[26] Hendrik Neubert,et al. Targeted quantitative proteomics for the analysis of 14 UGT1As and -2Bs in human liver using NanoUPLC-MS/MS with selected reaction monitoring. , 2013, Journal of proteome research.
[27] Fernand Labrie,et al. Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium. , 2004, The Journal of clinical endocrinology and metabolism.
[28] Takashi Baba,et al. Quantification of human uridine-diphosphate glucuronosyl transferase 1A isoforms in liver, intestine, and kidney using nanobore liquid chromatography-tandem mass spectrometry. , 2012, Analytical chemistry.
[29] Xinxin Ding,et al. Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues , 2012, Xenobiotica; the fate of foreign compounds in biological systems.
[30] L. Ekström,et al. Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues: changes from prenatal life to adulthood and in kidney cancer , 2013, Pharmacogenetics and genomics.
[31] C. Guillemette,et al. Deferiprone Glucuronidation by Human Tissues and Recombinant UDP Glucuronosyltransferase 1A6: An in Vitro Investigation of Genetic and Splice Variants , 2009, Drug Metabolism and Disposition.
[32] Yannick Duguay,et al. Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone. , 2006, Cancer research.
[33] R. Tukey,et al. Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes , 2001, British journal of pharmacology.
[34] E. Guo,et al. Sorafenib Metabolism Is Significantly Altered in the Liver Tumor Tissue of Hepatocellular Carcinoma Patient , 2014, PloS one.
[35] K. Knights,et al. Human Renal Cortical and Medullary UDP-Glucuronosyltransferases (UGTs): Immunohistochemical Localization of UGT2B7 and UGT1A Enzymes and Kinetic Characterization of S-Naproxen Glucuronidation , 2007, Journal of Pharmacology and Experimental Therapeutics.
[36] X. Chu,et al. Metabolism and Renal Elimination of Gaboxadol in Humans: Role of UDP-Glucuronosyltransferases and Transporters , 2009, Pharmaceutical Research.