Bacteraemia caused by Actinobaculum schaalii: An overlooked pathogen?

Abstract Actinobaculum schaalii is a uropathogen resistant to ciprofloxacin and trimethoprim–sulfamethoxazole. It requires a long culture time and specific conditions, and is therefore easily overgrown by other bacteria and regarded as part of the normal bacterial flora. We review 17 cases of A. schaalii bacteraemia, demonstrating its invasive potential. A. schaalii should always be ruled out as causative agent in patients with urinary tract infection or urosepticaemia with treatment failure.

[1]  V. Cattoir Actinobaculum schaalii: review of an emerging uropathogen. , 2012, The Journal of infection.

[2]  L. Lund,et al.  Actinobaculum schaalii in urological patients, screened with real-time polymerase chain reaction , 2011, Scandinavian journal of urology and nephrology.

[3]  S. Tschudin-Sutter,et al.  Actinobaculum schaalii - invasive pathogen or innocent bystander? A retrospective observational study , 2011, BMC infectious diseases.

[4]  K. Jaton,et al.  Actinobaculum schaalii: clinical observation of 20 cases. , 2011, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[5]  Gilbert GREUB,et al.  In vitro susceptibility of Actinobaculum schaalii to 12 antimicrobial agents and molecular analysis of fluoroquinolone resistance. , 2010, The Journal of antimicrobial chemotherapy.

[6]  H. Nielsen,et al.  Actinobaculum schaalii: A common cause of urinary tract infection in the elderly population. Bacteriological and clinical characteristics , 2010, Scandinavian journal of infectious diseases.

[7]  K. Søby,et al.  Actinobaculum schaalii, a Common Uropathogen in Elderly Patients, Denmark , 2010, Emerging infectious diseases.

[8]  N. Højlyng,et al.  Ten Cases of Actinobaculum schaalii Infection: Clinical Relevance, Bacterial Identification, and Antibiotic Susceptibility , 2005, Journal of Clinical Microbiology.

[9]  P. Lawson,et al.  Characterization of some Actinomyces-like isolates from human clinical specimens: reclassification of Actinomyces suis (Soltys and Spratling) as Actinobaculum suis comb. nov. and description of Actinobaculum schaalii sp. nov. , 1997, International journal of systematic bacteriology.