Synergistic anti-cancer and attenuation effects of thymosin on chemotherapeutic drug vinorelbine in tumor-bearing zebrafish.

[1]  Zhichang Qiu,et al.  Preparation and Characterization of Ginger Peel Polysaccharide–Zn (II) Complexes and Evaluation of Anti-Inflammatory Activity , 2022, Antioxidants.

[2]  Junjie Zhao,et al.  Effect of Thymosin on Inflammatory Factor Levels, Immune Function, and Quality of Life in Lung Cancer Patients Undergoing Radical Thoracoscopic Surgery , 2022, Evidence-based complementary and alternative medicine : eCAM.

[3]  J. Guo,et al.  Efficacy of thymosin α1 in management of radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy: A Phase 2 Clinical Trial (GASTO-1043). , 2022, International journal of radiation oncology, biology, physics.

[4]  Qiuhui Qian,et al.  Triclosan induced zebrafish immunotoxicity by targeting miR-19a and its gene socs3b to activate IL-6/STAT3 signaling pathway. , 2022, The Science of the total environment.

[5]  Siyi Qian,et al.  Zebrafish xenograft model for studying mechanism and treatment of non-small cell lung cancer brain metastasis , 2021, Journal of Experimental & Clinical Cancer Research.

[6]  M. Tsuboi,et al.  Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non–Small-Cell Lung Cancer With EGFR Mutation (IMPACT) , 2021, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[7]  R. White,et al.  Zebrafish as a New Model to Study the Crosstalk between Tumor and Host Metabolism. , 2021, Trends in cancer.

[8]  Yongdong Feng,et al.  The Efficacy and Safety of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Combined With Thymosin in Advanced Non-Small Cell Lung Cancer Patients Harboring Active Epidermal Growth Factor Receptor Mutations , 2021, Frontiers in Oncology.

[9]  Wei-Zhuo Tang,et al.  Ultrasound-assisted extraction of four groups of Osmanthus fragrans fruit: Optimization, UPLC-Orbitrap-MS/MS characterization and anti-inflammatory activity evaluation , 2021 .

[10]  N. Zhou,et al.  PTEN/AKT upregulation of TMSB10 contributes to lung cancer cell growth and predicts poor survival of the patients. , 2020, Bioscience, biotechnology, and biochemistry.

[11]  Ying Cheng,et al.  Gefitinib Versus Vinorelbine Plus Cisplatin as Adjuvant Treatment for Stage II-IIIA (N1-N2) EGFR-Mutant NSCLC: Final Overall Survival Analysis of CTONG1104 Phase III Trial , 2020, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[12]  Sarabjot Singh Makkar,et al.  Thymosin alpha 1: A comprehensive review of the literature , 2020, World journal of virology.

[13]  D. Ahmed,et al.  Antitumor and immunomodulatory effects of thymosin against tumor growth in mice. , 2020, Pakistan journal of pharmaceutical sciences.

[14]  K. Cui,et al.  Thymosin alpha-1 blocks the accumulation of myeloid suppressor cells in NSCLC by inhibiting VEGF production. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[15]  P. Mosci,et al.  Thymosin α1 protects from CTLA-4 intestinal immunopathology , 2020, Life Science Alliance.

[16]  Li Yang,et al.  Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma , 2020, Respiratory Research.

[17]  D. Rossi Metronomic oral vinorelbine and lung cancer therapy during the COVID 19 pandemic: A single-center experience , 2020, Lung Cancer.

[18]  Jia Hua Cheng,et al.  Zebrafish xenograft model of human lung cancer for studying the function of LINC00152 in cell proliferation and invasion , 2020, Cancer Cell International.

[19]  N. Mukaida,et al.  Cancer Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Is Dispensable for the Progression of 4T1 Murine Breast Cancer , 2019, International journal of molecular sciences.

[20]  L. Romani,et al.  A Reappraisal of Thymosin Alpha1 in Cancer Therapy , 2019, Front. Oncol..

[21]  Mi-Young Lee,et al.  Ameliorative effect of chlorin e6-mediated photodynamic therapy on DNCB-induced atopic dermatitis-like skin lesions in mice , 2019, Molecular & Cellular Toxicology.

[22]  A. Asoodeh,et al.  Thymosin alpha‐1; a natural peptide inhibits cellular proliferation, cell migration, the level of reactive oxygen species and promotes the activity of antioxidant enzymes in human lung epithelial adenocarcinoma cell line (A549) , 2019, Environmental toxicology.

[23]  Hui-Ting Yang,et al.  Thymosin participates in antimicrobial immunity in zebrafish , 2019, Fish & shellfish immunology.

[24]  J. Galon,et al.  Approaches to treat immune hot, altered and cold tumours with combination immunotherapies , 2019, Nature Reviews Drug Discovery.

[25]  Y. Liu,et al.  Comparison of efficacy and toxicity of bevacizumab, endostar and apatinib in transgenic and human lung cancer xenograftzebrafish model , 2018, Scientific Reports.

[26]  Qinghua Zhou,et al.  Thymosin α1 suppresses migration and invasion of PD-L1 high-expressing non-small-cell lung cancer cells via inhibition of STAT3–MMP2 signaling , 2018, OncoTargets and therapy.

[27]  A. Escande,et al.  Oral vinorelbine-based concomitant chemoradiotherapy in unresectable stage III non-small cell lung cancer: a systematic review , 2018, Expert review of anticancer therapy.

[28]  Ming-jun Wang,et al.  Murrangatin suppresses angiogenesis induced by tumor cell–derived media and inhibits AKT activation in zebrafish and endothelial cells , 2018, Drug design, development and therapy.

[29]  Xingzhen Lao,et al.  Thymosin Alpha1-Fc Modulates the Immune System and Down-regulates the Progression of Melanoma and Breast Cancer with a Prolonged Half-life , 2018, Scientific Reports.

[30]  Xingzhen Lao,et al.  Immunomodulatory and enhanced antitumor activity of a modified thymosin &agr;1 in melanoma and lung cancer , 2018, International journal of pharmaceutics.

[31]  L. Zon,et al.  EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay , 2017, The Journal of experimental medicine.

[32]  Kang-Yun Lee,et al.  Escape from IFN-γ-dependent immunosurveillance in tumorigenesis , 2017, Journal of Biomedical Science.

[33]  X. Xiong,et al.  Meisoindigo, but not its core chemical structure indirubin, inhibits zebrafish interstitial leukocyte chemotactic migration , 2016, Pharmaceutical biology.

[34]  Xiangnan Li,et al.  Thymosin α1 promotes the activation of myeloid-derived suppressor cells in a Lewis lung cancer model by upregulating Arginase 1. , 2015, Biochemical and biophysical research communications.

[35]  M. Sonobe,et al.  Phase II study of adjuvant vinorelbine and cisplatin in Japanese patients with completely resected stage II and III non-small cell lung cancer , 2014, Cancer Chemotherapy and Pharmacology.

[36]  P. McGrath,et al.  Use of zebrafish apoptosis assays for preclinical drug discovery , 2013, Expert opinion on drug discovery.

[37]  A. Ashkenazi,et al.  The zebrafish as a model organism for the study of apoptosis , 2010, Apoptosis.

[38]  T. Moody Thymosin α1 as a Chemopreventive Agent in Lung and Breast Cancer , 2007 .

[39]  A. Dicker,et al.  Zebrafish: An Emerging Model System for Human Disease and Drug Discovery , 2007, Clinical pharmacology and therapeutics.

[40]  G. Rasi,et al.  Thymosin α1 , 2007 .

[41]  G. Rasi,et al.  Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance. , 2006, Blood.

[42]  T. Moody,et al.  Thymosinα1 is chemopreventive for lung adenoma formation in A/J mice , 2000 .

[43]  D. Singer,et al.  Thymosin‐α1 regulates MHC class I expression in FRTL‐5 cells at transcriptional level , 2000 .

[44]  G. Rasi,et al.  Sequential chemoimmunotherapy for advanced non-small cell lung cancer using cisplatin, etoposide, thymosin-αl and interferon-α2a , 1995 .

[45]  J. W. Hilton Hypervitaminosis A in rainbow trout (Salmo gairdneri): toxicity signs and maximum tolerable level. , 1983, The Journal of nutrition.

[46]  G. Marshall,et al.  CURRENT STATUS OF THYMOSIN RESEARCH: EVIDENCE FOR THE EXISTENCE OF A FAMILY OF THYMIC FACTORS THAT CONTROL T‐CELL MATURATION * , 1979, Annals of the New York Academy of Sciences.

[47]  S. Fortin,et al.  Effectiveness of adjuvant carboplatin-based chemotherapy compared to cisplatin in non-small cell lung cancer , 2019, Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners.

[48]  C. Riccardi,et al.  Modulation of natural killer activity by thymosin alpha 1 and interferon , 2004, Cancer Immunology, Immunotherapy.

[49]  T. Moody,et al.  Thymosin alpha 1 down-regulates the growth of human non-small cell lung cancer cells in vitro and in vivo. , 1993, Cancer research.