Tremendous efforts have been paid for realization of fault-tolerant quantum computation so far. However, preexisting fault-tolerant schemes assume that a lot of qubits live together in a single quantum system, which is incompatible with actual situations of experiment. Here we propose a novel architecture for practically scalable quantum computation, where quantum computation is distributed over small-size (four-qubit) local systems, which are connected by quantum channels. We show that the proposed architecture works even with the error probability 0.1% of local operations, which breaks through the consensus by one order of magnitude. Furthermore, the fidelity of quantum channels can be very low $\sim$ 0.7, which substantially relaxes the difficulty of scaling-up the architecture. All key elements and their accuracy required for the present architecture are within reach of current technology. The present architecture allows us to achieve efficient scaling of quantum computer, as has been achieved in today's classical computer.