Some Experiments and Directions in Molecular Computing and Robotics

In this review I present a chemist’s perspective on molecular computing and molecular robotics. I start with nucleic acid catalysts and then show how the application of some concepts from computer sciences and macroscopic robotics enable engineering of interesting behaviors in molecular systems.

[1]  D. Stefanovic,et al.  Training a molecular automaton to play a game. , 2010, Nature nanotechnology.

[2]  Gonen Ashkenasy,et al.  Boolean logic functions of a synthetic peptide network. , 2004, Journal of the American Chemical Society.

[3]  R. Breaker Engineered allosteric ribozymes as biosensor components. , 2002, Current opinion in biotechnology.

[4]  Darko Stefanovic,et al.  Deoxyribozyme-based logic gates. , 2002, Journal of the American Chemical Society.

[5]  Rodney A. Brooks,et al.  Intelligence Without Reason , 1991, IJCAI.

[6]  Vladimir Privman,et al.  Enzyme-based logic systems for information processing. , 2009, Chemical Society reviews.

[7]  Itamar Willner,et al.  All-DNA finite-state automata with finite memory , 2010, Proceedings of the National Academy of Sciences.

[8]  Erik Winfree,et al.  Molecular robots guided by prescriptive landscapes , 2010, Nature.

[9]  Darko Stefanovic,et al.  A deoxyribozyme-based molecular automaton , 2003, Nature Biotechnology.

[10]  Sanjay Tyagi,et al.  Molecular Beacons: Probes that Fluoresce upon Hybridization , 1996, Nature Biotechnology.

[11]  Darko Stefanovic,et al.  Behavior of polycatalytic assemblies in a substrate-displaying matrix. , 2006, Journal of the American Chemical Society.

[12]  Tibor Antal,et al.  Molecular spiders with memory. , 2007, Physical review. E, Statistical, nonlinear, and soft matter physics.

[13]  P. Rothemund Folding DNA to create nanoscale shapes and patterns , 2006, Nature.

[14]  A. P. D. S. and,et al.  Proof-of-Principle of Molecular-Scale Arithmetic , 2000 .