Resolving the neural circuits of anxiety

[1]  Andrea Klug,et al.  The Hippocampus Book , 2016 .

[2]  David E. Moorman,et al.  Neural mechanisms regulating different forms of risk-related decision-making: Insights from animal models , 2015, Neuroscience & Biobehavioral Reviews.

[3]  A. Lüthi,et al.  Neuronal circuits for fear and anxiety , 2015, Nature Reviews Neuroscience.

[4]  Do P. M. Tromp,et al.  Extending the amygdala in theories of threat processing , 2015, Trends in Neurosciences.

[5]  Alfred Anwander,et al.  Emotion Regulation and Trait Anxiety Are Predicted by the Microstructure of Fibers between Amygdala and Prefrontal Cortex , 2015, The Journal of Neuroscience.

[6]  E. Coutinho,et al.  The impact of posttraumatic symptoms and comorbid mental disorders on the health-related quality of life in treatment-seeking PTSD patients. , 2015, Comprehensive psychiatry.

[7]  Ian R. Wickersham,et al.  A Circuit Mechanism for Differentiating Positive and Negative Associations , 2015, Nature.

[8]  R. Paz,et al.  Amygdala–prefrontal interactions in (mal)adaptive learning , 2015, Trends in Neurosciences.

[9]  Stephen A. Allsop,et al.  Decoding Neural Circuits that Control Compulsive Sucrose Seeking , 2015, Cell.

[10]  K. Tye,et al.  From circuits to behaviour in the amygdala , 2015, Nature.

[11]  Gregory J. Quirk,et al.  A temporal shift in the circuits mediating retrieval of fear memory , 2014, Nature.

[12]  Jason Tucciarone,et al.  The paraventricular thalamus controls a central amygdala fear circuit , 2014, Nature.

[13]  Cyril Herry,et al.  Encoding of fear learning and memory in distributed neuronal circuits , 2014, Nature Neuroscience.

[14]  R. Clem,et al.  Pathway-Selective Adjustment of Prefrontal-Amygdala Transmission during Fear Encoding , 2014, The Journal of Neuroscience.

[15]  Gary A. Kane,et al.  Gap Junctions in the Ventral Hippocampal-Medial Prefrontal Pathway Are Involved in Anxiety Regulation , 2014, The Journal of Neuroscience.

[16]  P. O’Donnell,et al.  Amygdala Inputs to the Prefrontal Cortex Elicit Heterosynaptic Suppression of Hippocampal Inputs , 2014, The Journal of Neuroscience.

[17]  K. Tye.  Neural Circuit Reprogramming: A New Paradigm for Treating Neuropsychiatric Disease? , 2014, Neuron.

[18]  Joshua A. Gordon,et al.  Fear and Safety Engage Competing Patterns of Theta-Gamma Coupling in the Basolateral Amygdala , 2014, Neuron.

[19]  M. Kinch,et al.  An overview of FDA-approved new molecular entities: 1827-2013. , 2014, Drug discovery today.

[20]  David J. Anderson,et al.  Central amygdala PKC-δ+ neurons mediate the influence of multiple anorexigenic signals , 2014, Nature Neuroscience.

[21]  Stephen A. Allsop,et al.  Optogenetic insights on the relationship between anxiety-related behaviors and social deficits , 2014, Front. Behav. Neurosci..

[22]  D. Paré,et al.  Amygdala Microcircuits Controlling Learned Fear , 2014, Neuron.

[23]  Sadegh Nabavi,et al.  Engineering a memory with LTD and LTP , 2014, Nature.

[24]  Alice M Stamatakis,et al.  Inhibition of projections from the basolateral amygdala to the entorhinal cortex disrupts the acquisition of contextual fear , 2014, Front. Behav. Neurosci..

[25]  Avishek Adhikari,et al.  Behavioral Neuroscience Mini Review Article Distributed Circuits Underlying Anxiety , 2022 .

[26]  David J. Anderson,et al.  A Framework for Studying Emotions across Species , 2014, Cell.

[27]  M. Penzo,et al.  Fear Conditioning Potentiates Synaptic Transmission onto Long-Range Projection Neurons in the Lateral Subdivision of Central Amygdala , 2014, The Journal of Neuroscience.

[28]  Menno P. Witter,et al.  Architecture of spatial circuits in the hippocampal region , 2014, Philosophical Transactions of the Royal Society B: Biological Sciences.

[29]  Alice M Stamatakis,et al.  Amygdala and bed nucleus of the stria terminalis circuitry: Implications for addiction-related behaviors , 2014, Neuropharmacology.

[30]  David J. Anderson,et al.  Control of Stress-Induced Persistent Anxiety by an Extra-Amygdala Septohypothalamic Circuit , 2014, Cell.

[31]  Johannes J. Letzkus,et al.  Long-Range Connectivity Defines Behavioral Specificity of Amygdala Neurons , 2014, Neuron.

[32]  A. Lüthi,et al.  Ex vivo dissection of optogenetically activated mPFC and hippocampal inputs to neurons in the basolateral amygdala: implications for fear and emotional memory , 2014, Front. Behav. Neurosci..

[33]  Nikolaos Karalis,et al.  Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression , 2013, Nature.

[34]  Joshua A. Gordon,et al.  Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety , 2013, Nature Neuroscience.

[35]  Harry B. M. Uylings,et al.  Comparison of (stereotactic) parcellations in mouse prefrontal cortex , 2014, Brain Structure and Function.

[36]  Christian Himpe,et al.  Directional Theta Coherence in Prefrontal Cortical to Amygdalo-Hippocampal Pathways Signals Fear Extinction , 2013, PloS one.

[37]  L. Quevedo,et al.  Anxiety disorders in young people: a population-based study. , 2013, Revista brasileira de psiquiatria.

[38]  K. Tye,et al.  BLA to vHPC Inputs Modulate Anxiety-Related Behaviors , 2013, Neuron.

[39]  James H. Marshel,et al.  Diverging neural pathways assemble a behavioural state from separable features in anxiety , 2013, Nature.

[40]  P. O’Donnell,et al.  Closing the Gate in the Limbic Striatum: Prefrontal Suppression of Hippocampal and Thalamic Inputs , 2013, Neuron.

[41]  Alice M Stamatakis,et al.  Distinct extended amygdala circuits for divergent motivational states , 2013, Nature.

[42]  Hongkui Zeng,et al.  Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus , 2013, Neuron.

[43]  S. Sternson.  Hypothalamic Survival Circuits: Blueprints for Purposive Behaviors , 2013, Neuron.

[44]  David E. Moorman,et al.  Posttraining optogenetic manipulations of basolateral amygdala activity modulate consolidation of inhibitory avoidance memory in rats , 2013, Proceedings of the National Academy of Sciences.

[45]  Charles D. Kopec,et al.  Experience-dependent modification of a central amygdala fear circuit , 2013, Nature Neuroscience.

[46]  R. Wise,et al.  Synaptic and Behavioral Profile of Multiple Glutamatergic Inputs to the Nucleus Accumbens , 2012, Neuron.

[47]  P. Fitzgerald,et al.  Chronic alcohol remodels prefrontal neurons and disrupts NMDA receptor-mediated fear extinction encoding , 2012, Nature Neuroscience.

[48]  C. Stark,et al.  Functional MRI of the amygdala and bed nucleus of the stria terminalis during conditions of uncertainty in generalized anxiety disorder. , 2012, Journal of psychiatric research.

[49]  R. Paz,et al.  Amygdala-Prefrontal Synchronization Underlies Resistance to Extinction of Aversive Memories , 2012, Neuron.

[50]  A. Holmes,et al.  Enhanced Extinction of Aversive Memories by High-Frequency Stimulation of the Rat Infralimbic Cortex , 2012, PloS one.

[51]  K. Deisseroth,et al.  Optogenetic investigation of neural circuits underlying brain disease in animal models , 2012, Nature Reviews Neuroscience.

[52]  Joseph E LeDoux.  Rethinking the Emotional Brain , 2012, Neuron.

[53]  P. Whalen,et al.  The structural and functional connectivity of the amygdala: From normal emotion to pathological anxiety , 2011, Behavioural Brain Research.

[54]  Avishek Adhikari,et al.  Single Units in the Medial Prefrontal Cortex with Anxiety-Related Firing Patterns Are Preferentially Influenced by Ventral Hippocampal Activity , 2011, Neuron.

[55]  Joshua H. Jennings,et al.  Safety Signals Mitigate the Consequences of Uncontrollable Stress Via a Circuit Involving the Sensory Insular Cortex and Bed Nucleus of the Stria Terminalis , 2011, Biological Psychiatry.

[56]  C. Robinet,et al.  Oxytocin Selectively Gates Fear Responses Through Distinct Outputs from the Central Amygdala , 2011, Science.

[57]  Rajeevan T. Narayanan,et al.  Patterns of Coupled Theta Activity in Amygdala-Hippocampal-Prefrontal Cortical Circuits during Fear Extinction , 2011, PloS one.

[58]  Longnian Lin,et al.  Neurons in the Amygdala with Response-Selectivity for Anxiety in Two Ethologically Based Tests , 2011, PloS one.

[59]  Lief E. Fenno,et al.  Amygdala circuitry mediating reversible and bidirectional control of anxiety , 2011, Nature.

[60]  S. Lilienfeld,et al.  Differences between trait fear and trait anxiety: implications for psychopathology. , 2011, Clinical psychology review.

[61]  David J. Anderson,et al.  Genetic dissection of an amygdala microcircuit that gates conditioned fear , 2010, Nature.

[62]  Michael B. Stadler,et al.  Encoding of conditioned fear in central amygdala inhibitory circuits , 2010, Nature.

[63]  M. Myers,et al.  Modulation of the mesolimbic dopamine system by leptin , 2010, Brain Research.

[64]  J. Berke,et al.  Single-Unit Activity in the Medial Prefrontal Cortex during Immediate and Delayed Extinction of Fear in Rats , 2010, PloS one.

[65]  Natalie L. Trent,et al.  The ventral hippocampus and the lateral septum work in tandem to regulate rats' open-arm exploration in the elevated plus-maze , 2010, Physiology & Behavior.

[66]  Andrew M. Poulos,et al.  Compensation in the neural circuitry of fear conditioning awakens learning circuits in the bed nuclei of the stria terminalis , 2010, Proceedings of the National Academy of Sciences.

[67]  Karl Deisseroth,et al.  Optical activation of lateral amygdala pyramidal cells instructs associative fear learning , 2010, Proceedings of the National Academy of Sciences.

[68]  P. Dechent,et al.  Reduced amygdalar and hippocampal size in adults with generalized social phobia. , 2010, Journal of psychiatry & neuroscience : JPN.

[69]  Mihir A. Topiwala,et al.  Synchronized Activity between the Ventral Hippocampus and the Medial Prefrontal Cortex during Anxiety , 2010, Neuron.

[70]  Wei Zhang,et al.  Review: A psychopharmacological treatment algorithm for generalised anxiety disorder (GAD) , 2010, Journal of psychopharmacology.

[71]  C. Grillon,et al.  Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety , 2010, Neuropsychopharmacology.

[72]  Katherine E. Prater,et al.  Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder. , 2009, Archives of general psychiatry.

[73]  G. Quirk,et al.  Sustained Conditioned Responses in Prelimbic Prefrontal Neurons Are Correlated with Fear Expression and Extinction Failure , 2009, The Journal of Neuroscience.

[74]  T. Einarson,et al.  Systematic review and quality assessment of economic evaluations and quality-of-life studies related to generalized anxiety disorder. , 2009, Clinical therapeutics.

[75]  Natalie L. M. Cappaert,et al.  The anatomy of memory: an interactive overview of the parahippocampal–hippocampal network , 2009, Nature Reviews Neuroscience.

[76]  E. Moser,et al.  Faculty Opinions recommendation of Entrainment of neocortical neurons and gamma oscillations by the hippocampal theta rhythm. , 2009 .

[77]  C. Darwin,et al.  The Expression of the Emotions in Man and Animals , 1956 .

[78]  Sean M Montgomery,et al.  Entrainment of Neocortical Neurons and Gamma Oscillations by the Hippocampal Theta Rhythm , 2008, Neuron.

[79]  A. Lüthi,et al.  Switching on and off fear by distinct neuronal circuits , 2008, Nature.

[80]  Kay M. Tye,et al.  Rapid strengthening of thalamo-amygdala synapses mediates cue–reward learning , 2008, Nature.

[81]  E. Hoffman,et al.  Anxiety disorders: a comprehensive review of pharmacotherapies. , 2008, The Mount Sinai journal of medicine, New York.

[82]  E. Hollander,et al.  Experimental therapeutics for refractory obsessive-compulsive disorder: translational approaches and new somatic developments. , 2008, The Mount Sinai journal of medicine, New York.

[83]  D. Murphy,et al.  The regular and light–dark Suok tests of anxiety and sensorimotor integration: utility for behavioral characterization in laboratory rodents , 2008, Nature Protocols.

[84]  Bernat Kocsis,et al.  Elicited hippocampal theta rhythm: a screen for anxiolytic and procognitive drugs through changes in hippocampal function? , 2007, Behavioural pharmacology.

[85]  Kay M. Tye,et al.  Amygdala Neurons Differentially Encode Motivation and Reinforcement , 2007, The Journal of Neuroscience.

[86]  Y. Lecrubier.  Widespread underrecognition and undertreatment of anxiety and mood disorders: results from 3 European studies. , 2007, The Journal of clinical psychiatry.

[87]  M. Walton,et al.  Calculating utility: preclinical evidence for cost–benefit analysis by mesolimbic dopamine , 2007, Psychopharmacology.

[88]  E. Prinssen,et al.  A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants. , 2006, European journal of pharmacology.

[89]  W. Vale,et al.  The Effect of Lateral Septum Corticotropin-Releasing Factor Receptor 2 Activation on Anxiety Is Modulated by Stress , 2006, The Journal of Neuroscience.

[90]  A. Beck,et al.  The empirical status of cognitive-behavioral therapy: a review of meta-analyses. , 2006, Clinical psychology review.

[91]  B. Balleine.  Neural bases of food-seeking: Affect, arousal and reward in corticostriatolimbic circuits , 2005, Physiology & Behavior.

[92]  M. Brandão,et al.  Changes in the biogenic amine content of the prefrontal cortex, amygdala, dorsal hippocampus, and nucleus accumbens of rats submitted to single and repeated sessions of the elevated plus-maze test. , 2005, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[93]  Olaf Sporns,et al.  The Human Connectome: A Structural Description of the Human Brain , 2005, PLoS Comput. Biol..

[94]  D. Paré,et al.  Prefrontal Control of the Amygdala , 2005, The Journal of Neuroscience.

[95]  Olga V. Demler,et al.  Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. , 2005, Archives of general psychiatry.

[96]  Olga V. Demler,et al.  Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. , 2005, Archives of general psychiatry.

[97]  W. Newsome,et al.  Choosing the greater of two goods: neural currencies for valuation and decision making , 2005, Nature Reviews Neuroscience.

[98]  J. Panksepp.  Affective consciousness: Core emotional feelings in animals and humans , 2005, Consciousness and Cognition.

[99]  C. Dourish,et al.  Behavioural and pharmacological characterisation of the elevated “zero-maze” as an animal model of anxiety , 1994, Psychopharmacology.

[100]  G. Quirk,et al.  Neuronal signalling of fear memory , 2004, Nature Reviews Neuroscience.

[101]  H. Markram,et al.  Interneurons of the neocortical inhibitory system , 2004, Nature Reviews Neuroscience.

[102]  Urs Gerber,et al.  A frequency-dependent switch from inhibition to excitation in a hippocampal unitary circuit , 2004, Nature.

[103]  G. Nomikos,et al.  Genetic deletion and pharmacological blockade of CB1 receptors modulates anxiety in the shock‐probe burying test , 2004, The European journal of neuroscience.

[104]  Brigitta B. Gundersen,et al.  Effects of Chronic Fluoxetine in Animal Models of Anxiety and Depression , 2004, Neuropsychopharmacology.

[105]  D. Treit,et al.  Anxiety is functionally segregated within the septo-hippocampal system , 2004, Brain Research.

[106]  S. File,et al.  The reliability of the hole-board apparatus , 1975, Psychopharmacologia.

[107]  J. Simiand,et al.  The staircase test in mice: A simple and efficient procedure for primary screening of anxiolytic agents , 2004, Psychopharmacology.

[108]  A. Grace,et al.  The Prefrontal Cortex Regulates Lateral Amygdala Neuronal Plasticity and Responses to Previously Conditioned Stimuli , 2003, The Journal of Neuroscience.

[109]  H. Anisman,et al.  Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice , 2003, Biological Psychiatry.

[110]  T. Seidenbecher,et al.  Amygdalar and Hippocampal Theta Rhythm Synchronization During Fear Memory Retrieval , 2003, Science.

[111]  C. Sánchez.  Stress-induced vocalisation in adult animals. A valid model of anxiety? , 2003, European journal of pharmacology.

[112]  Anthony A. Grace,et al.  Regulation of conditioned responses of basolateral amygdala neurons , 2002, Physiology & Behavior.

[113]  G. Quirk,et al.  Neurons in medial prefrontal cortex signal memory for fear extinction , 2002, Nature.

[114]  J. Gabrieli,et al.  Rethinking Feelings: An fMRI Study of the Cognitive Regulation of Emotion , 2002, Journal of Cognitive Neuroscience.

[115]  D. Marazziti,et al.  Do animal models of anxiety predict anxiolytic-like effects of antidepressants? , 2002, Psychopharmacology.

[116]  Eytan Ruppin,et al.  Actor-critic models of the basal ganglia: new anatomical and computational perspectives , 2002, Neural Networks.

[117]  M. Corbetta,et al.  Control of goal-directed and stimulus-driven attention in the brain , 2002, Nature Reviews Neuroscience.

[118]  Hong-wei Dong,et al.  Topography of projections from amygdala to bed nuclei of the stria terminalis , 2001, Brain Research Reviews.

[119]  G. Griebel,et al.  Measuring normal and pathological anxiety-like behaviour in mice: a review , 2001, Behavioural Brain Research.

[120]  M. Jung,et al.  Fast spiking and regular spiking neural correlates of fear conditioning in the medial prefrontal cortex of the rat. , 2001, Cerebral cortex.

[121]  Joseph E LeDoux.  Emotion circuits in the brain. , 2009, Annual review of neuroscience.

[122]  J. Gross.  The Emerging Field of Emotion Regulation: An Integrative Review , 1998 .

[123]  A. McDonald.  Cortical pathways to the mammalian amygdala , 1998, Progress in Neurobiology.

[124]  M. McKERNAN,et al.  Fear conditioning induces a lasting potentiation of synaptic currents in vitro , 1997, Nature.

[125]  R. Vertes,et al.  Brainstem-diencephalo-septohippocampal systems controlling the theta rhythm of the hippocampus. , 1997, Neuroscience.

[126]  Joseph E LeDoux,et al.  Fear conditioning induces associative long-term potentiation in the amygdala , 1997, Nature.

[127]  L. Swanson,et al.  Connections of the rat lateral septal complex 1 Published on the World Wide Web on 2 June 1997. 1 , 1997, Brain Research Reviews.

[128]  H. Groenewegen,et al.  The anatomical relationships of the prefrontal cortex with limbic structures and the basal ganglia , 1997, Journal of psychopharmacology.

[129]  R. Murray,et al.  A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders. , 1996, Molecular psychiatry.

[130]  K. Lesch,et al.  Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region , 1996, Science.

[131]  L. Swanson,et al.  Structural Evidence for Functional Domains in the Rat Hippocampus , 1996, Science.

[132]  Joseph E LeDoux,et al.  Fear conditioning enhances short-latency auditory responses of lateral amygdala neurons: Parallel recordings in the freely behaving rat , 1995, Neuron.

[133]  Joel L. Davis,et al.  Adaptive Critics and the Basal Ganglia , 1995 .

[134]  J. Herman,et al.  Ventral subicular interaction with the hypothalamic paraventricular nucleus: Evidence for a relay in the bed nucleus of the stria terminalis , 1993, The Journal of comparative neurology.

[135]  S. Handley,et al.  Evaluation of marble-burying behavior as a model of anxiety , 1991, Pharmacology Biochemistry and Behavior.

[136]  R. Lister.  Ethologically-based animal models of anxiety disorders. , 1990, Pharmacology & therapeutics.

[137]  N. Mackintosh,et al.  Neurobiology, psychology and habituation. , 1987, Behaviour research and therapy.

[138]  C. Gardner.  Distress vocalization in rat pups. A simple screening method for anxiolytic drugs. , 1985, Journal of pharmacological methods.

[139]  S. File,et al.  Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat , 1985, Journal of Neuroscience Methods.

[140]  S. File.  Animal models for predicting clinical efficacy of anxiolytic drugs: social behaviour. , 1985, Neuropsychobiology.

[141]  C. Bucherelli,et al.  Passive and active avoidance behavior in the light-dark box test , 1984, Physiology & Behavior.

[142]  H. Fibiger,et al.  Conditioned defensive burying: A new paradigm for the study of anxiolytic agents , 1981, Pharmacology Biochemistry and Behavior.

[143]  Douglas L. Jones,et al.  From motivation to action: Functional interface between the limbic system and the motor system , 1980, Progress in Neurobiology.

[144]  J. Russell.  A circumplex model of affect. , 1980 .

[145]  E. Kandel,et al.  Stimulus-response relations and stability of mechanoreceptor and motor neurons mediating defensive gill-withdrawal reflex in Aplysia. , 1978, Journal of neurophysiology.

[146]  C. L. Hull.  Principles of behavior : an introduction to behavior theory , 1943 .

[147]  Calvin Hall,et al.  A study of the rat's behavior in a field : a contribution to method in comparative psychology , 1932 .

[148]  Antoinette M. Feleky.  The expression of the emotions. , 1914 .

[149]  Sanger Brown,et al.  An Investigation into the Functions of the Occipital and Temporal Lobes of the Monkey's Brain , 1888 .

[150]  C. Darwin,et al.  The Expression of the Emotions in Man and Animals , 1872 .