Genome-wide association studies in oesophageal adenocarcinoma and Barrett’s oesophagus: a large-scale meta-analysis

Gharahkhani, Puya, Fitzgerald, Rebecca C, Vaughan, Thomas L, Palles, Claire, Gockel, Ines, Tomlinson, Ian, Buas, Matthew F, May, Andrea, Gerges, Christian, Anders, Mario, Becker, Jessica, Kreuser, Nicole, Noder, Tania, Venerito, Marino, Veits, Lothar, Schmidt, Thomas, Manner, Hendrik, Schmidt, Claudia, Hess, Timo, Böhmer, Anne C, Izbicki, Jakob R, Hölscher, Arnulf H, Lang, Hauke, Lorenz, Dietmar, Schumacher, Brigitte, Hackelsberger, Andreas, Mayershofer, Rupert, Pech, Oliver, Vashist, Yogesh, Ott, Katja, Vieth, Michael, Weismüller, Josef, Nöthen, Markus M, Attwood, Stephen, Barr, Hugh, Chegwidden, Laura, de Caestecker, John, Harrison, Rebecca, Love, Sharon B, MacDonald, David, Moayyedi, Paul, Prenen, Hans, Watson, R G Peter, Iyer, Prasad G, Anderson, Lesley A, Bernstein, Leslie, Chow, Wong-Ho, Hardie, Laura J, Lagergren, Jesper, Liu, Geoffrey, Risch, Harvey A, Wu, Anna H, Ye, Weimin, Bird, Nigel C, Shaheen, Nicholas J, Gammon, Marilie D, Corley, Douglas A, Caldas, Carlos, Moebus, Susanne, Knapp, Michael, Peters, Wilbert H M, Neuhaus, Horst, Rösch, Thomas, Ell, Christian, MacGregor, Stuart, Pharoah, Paul, Whiteman, David C, Jankowski, Janusz and Schumacher, Johannes

[1]  G. Moy,et al.  ABCC5 is required for cAMP-mediated hindgut invagination in sea urchin embryos , 2015, Development.

[2]  E. Steyerberg,et al.  Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial. , 2015, The Lancet. Oncology.

[3]  Ross M. Fraser,et al.  Genetic studies of body mass index yield new insights for obesity biology , 2015, Nature.

[4]  C. Wijmenga,et al.  Polymorphisms Near TBX 5 and GDF 7 Are Associated With Increased Risk for Barrett ’ s , 2017 .

[5]  J. Hirschhorn,et al.  Biological interpretation of genome-wide association studies using predicted gene functions , 2015, Nature Communications.

[6]  E. DiMango,et al.  Prevalence of gastroesophageal reflux in cystic fibrosis and implications for lung disease. , 2014, Annals of the American Thoracic Society.

[7]  Olivier Delaneau,et al.  Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel , 2014, Nature Communications.

[8]  T. Spector,et al.  Germline genetic contributions to risk for esophageal adenocarcinoma, Barrett's esophagus, and gastroesophageal reflux. , 2013, Journal of the National Cancer Institute.

[9]  Joseph K. Pickrell.  Joint analysis of functional genomic data and genome-wide association studies of 18 human traits , 2013, bioRxiv.

[10]  M. Peters,et al.  Systematic identification of trans eQTLs as putative drivers of known disease associations , 2013, Nature Genetics.

[11]  P. Souček,et al.  Differences in Transcript Levels of ABC Transporters Between Pancreatic Adenocarcinoma and Nonneoplastic Tissues , 2013, Pancreas.

[12]  J. Andrici,et al.  Hiatal hernia and the risk of Barrett's esophagus , 2013, Journal of gastroenterology and hepatology.

[13]  Emily A. Knapp,et al.  Cancer risk in cystic fibrosis: a 20-year nationwide study from the United States. , 2013, Journal of the National Cancer Institute.

[14]  Simon C. Potter,et al.  Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett’s esophagus , 2012, Nature Genetics.

[15]  L. Dupont,et al.  Mechanisms of Increased Gastroesophageal Reflux in Patients With Cystic Fibrosis , 2012, The American Journal of Gastroenterology.

[16]  J. Marchini,et al.  Fast and accurate genotype imputation in genome-wide association studies through pre-phasing , 2012, Nature Genetics.

[17]  Kenneth K Wang,et al.  Epithelial mesenchymal transition and cancer stem cells in esophageal adenocarcinoma originating from Barrett's esophagus. , 2012, Oncology letters.

[18]  Sampsa Hautaniemi,et al.  Candidate driver genes in microsatellite‐unstable colorectal cancer , 2012, International journal of cancer.

[19]  O. Delaneau,et al.  A linear complexity phasing method for thousands of genomes , 2011, Nature Methods.

[20]  Manolis Kellis,et al.  HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants , 2011, Nucleic Acids Res..

[21]  H. Sørensen,et al.  Incidence of adenocarcinoma among patients with Barrett's esophagus. , 2011, The New England journal of medicine.

[22]  P. Visscher,et al.  A versatile gene-based test for genome-wide association studies. , 2010, American journal of human genetics.

[23]  Yun Li,et al.  METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..

[24]  B. Reid,et al.  Barrett's oesophagus and oesophageal adenocarcinoma: time for a new synthesis , 2010, Nature Reviews Cancer.

[25]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[26]  E. Xenos.  The role of esophageal motility and hiatal hernia in esophageal exposure to acid , 2002, Surgical Endoscopy And Other Interventional Techniques.

[27]  Tanya M. Teslovich,et al.  LocusZoom: regional visualization of genome-wide association scan results , 2010, Bioinform..

[28]  P. Dítě,et al.  [Barrett's esophagus]. , 2000, Bratislavske lekarske listy.

[29]  L. Tsui,et al.  Identification of the cystic fibrosis gene: genetic analysis. , 1989, Science.

[30]  P. Marchand.  The anatomy of esophageal hiatus of the diaphragm and the pathogenesis of hiatus herniation. , 1959, The Journal of thoracic surgery.