Interplay Between SAFE and RISK Pathways in Sphingosine-1-Phosphate–Induced Cardioprotection

[1]  D. Henrion,et al.  RISK and SAFE signaling pathway interactions in remote limb ischemic perconditioning in combination with local ischemic postconditioning , 2011, Basic Research in Cardiology.

[2]  E. Raddatz,et al.  STAT3α interacts with nuclear GSK3beta and cytoplasmic RISK pathway and stabilizes rhythm in the anoxic-reoxygenated embryonic heart , 2011, Basic Research in Cardiology.

[3]  R. DePinho,et al.  FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress* , 2010, The Journal of Biological Chemistry.

[4]  N. Hariharan,et al.  Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion , 2010, Circulation.

[5]  G. Heusch,et al.  Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion , 2010, Basic Research in Cardiology.

[6]  L. Opie,et al.  Ethanolamine is a novel STAT-3 dependent cardioprotective agent , 2010, Basic Research in Cardiology.

[7]  G. Heusch,et al.  TNFalpha in atherosclerosis, myocardial ischemia/reperfusion and heart failure. , 2010, Pharmacology & therapeutics.

[8]  L. Opie,et al.  TNFα protects cardiac mitochondria independently of its cell surface receptors , 2010, Basic Research in Cardiology.

[9]  R. Erbel,et al.  Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease , 2010, Basic Research in Cardiology.

[10]  L. Opie,et al.  Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway. , 2009, Cardiovascular research.

[11]  S. Lecour Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway? , 2009, Journal of molecular and cellular cardiology.

[12]  R. James,et al.  Native and reconstituted HDL activate Stat3 in ventricular cardiomyocytes via ERK1/2: role of sphingosine-1-phosphate. , 2008, Cardiovascular research.

[13]  J. Karliner Sphingosine Kinase and Sphingosine 1-Phosphate in Cardioprotection , 2009, Journal of cardiovascular pharmacology.

[14]  D. Das,et al.  Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol. , 2009, Free radical biology & medicine.

[15]  P. Fawcett,et al.  Function of Mitochondrial Stat3 in Cellular Respiration , 2009, Science.

[16]  G. Heusch,et al.  Ischemic Postconditioning in Pigs: No Causal Role for Risk Activation , 2008, Circulation research.

[17]  H. Drexler,et al.  The myocardial JAK/STAT pathway: from protection to failure. , 2008, Pharmacology & therapeutics.

[18]  J. Karliner,et al.  Combined sphingosine, S1P and ischemic postconditioning rescue the heart after protracted ischemia. , 2008, Biochemical and biophysical research communications.

[19]  L. Opie,et al.  Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning. , 2008, Cardiovascular research.

[20]  L. Opie,et al.  Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion , 2008, Basic Research in Cardiology.

[21]  W. Argraves,et al.  Hdl Serves as a S1p Signaling Platform Mediating a Multitude of Cardiovascular Effects the Source of S1p in Blood , 2022 .

[22]  G. Booz,et al.  Can the Protective Actions of JAK-STAT in the Heart be Exploited Therapeutically? Parsing the Regulation of Interleukin-6-Type Cytokine Signaling , 2007, Journal of cardiovascular pharmacology.

[23]  J. Omens,et al.  Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. , 2007, American journal of physiology. Heart and circulatory physiology.

[24]  J. Stypmann,et al.  High-Density Lipoproteins and Their Constituent, Sphingosine-1-Phosphate, Directly Protect the Heart Against Ischemia/Reperfusion Injury In Vivo via the S1P3 Lysophospholipid Receptor , 2006, Circulation.

[25]  D. Castrillon,et al.  Foxo Transcription Factors Blunt Cardiac Hypertrophy by Inhibiting Calcineurin Signaling , 2006, Circulation.

[26]  L. Opie,et al.  Pharmacological Preconditioning With Tumor Necrosis Factor-α Activates Signal Transducer and Activator of Transcription-3 at Reperfusion Without Involving Classic Prosurvival Kinases (Akt and Extracellular Signal–Regulated Kinase) , 2005, Circulation.

[27]  V. Natarajan,et al.  Quantitative analysis of sphingoid base-1-phosphates as bisacetylated derivatives by liquid chromatography-tandem mass spectrometry. , 2005, Analytical biochemistry.

[28]  S. Akira,et al.  Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning. , 2004, Cardiovascular research.

[29]  J. Karliner Mechanisms of cardioprotection by lysophospholipids , 2004, Journal of cellular biochemistry.

[30]  M. Mocanu,et al.  Postconditioning: A Form of “Modified Reperfusion” Protects the Myocardium by Activating the Phosphatidylinositol 3-Kinase–Akt Pathway , 2004, Circulation research.

[31]  N. Gray,et al.  Sphingosine 1-Phosphate (S1P) Receptor Subtypes S1P1 and S1P3, Respectively, Regulate Lymphocyte Recirculation and Heart Rate* , 2004, Journal of Biological Chemistry.

[32]  N. Gray,et al.  Sphingosine 1-Phosphate ( S 1 P ) Receptor Subtypes S 1 P 1 and S 1 P 3 , Respectively , Regulate Lymphocyte Recirculation and Heart Rate * , 2004 .

[33]  T. Ohmori,et al.  Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2. , 2003, Cardiovascular research.

[34]  M. Sack,et al.  Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene. , 2002, Cardiovascular research.

[35]  L. Opie,et al.  Identification of a novel role for sphingolipid signaling in TNF alpha and ischemic preconditioning mediated cardioprotection. , 2002, Journal of molecular and cellular cardiology.

[36]  N. Maulik,et al.  JAK/STAT Signaling Is Associated With Cardiac Dysfunction During Ischemia and Reperfusion , 2001, Circulation.

[37]  根来 伸治 Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction , 2001 .

[38]  M. Ui,et al.  Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. , 2000, The Biochemical journal.