Genome-wide association analysis of excessive daytime sleepiness identifies 42 loci that suggest phenotypic subgroups
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Max A. Little | Samuel E. Jones | J. Lane | S. Anderson | S. Kyle | D. Bechtold | M. Little | A. Loudon | R. Emsley | F. Scheer | D. Lawlor | S. Redline | D. Ray | M. Rutter | R. Saxena | K. Kristiansson | T. Paunio | J. Tyrrell | T. Frayling | M. Weedon | S. Purcell | C. Willer | B. Cade | T. Sofer | Xiaofeng Zhu | J. Nielsen | A. Wood | K. Hveem | J. Bowden | K. Spiegelhalder | H. Dashti | V. V. van Hees | J. Zwart | B. Brumpton | B. Winsvold | Heming Wang | R. Richmond | K. Kantojärvi | H. Ollila | L. Strand | Yanwei Song | K. Patel | S. Sulkava | J. Nielsen | R. Saxena | S. Jones | Xiaofeng Zhu
[1] Gad Getz,et al. Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis , 2018, PLoS medicine.
[2] Chun Jimmie Ye,et al. Narcolepsy risk loci are enriched in immune cells and suggest autoimmune modulation of the T cell receptor repertoire , 2018, bioRxiv.
[3] Sebastiaan Overeem,et al. Exploring the clinical features of narcolepsy type 1 versus narcolepsy type 2 from European Narcolepsy Network database with machine learning , 2018, Scientific Reports.
[4] A. Pack,et al. Candidate gene analysis in the São Paulo Epidemiologic Sleep Study (EPISONO) shows an association of variant in PDE4D and sleepiness. , 2018, Sleep medicine.
[5] Jack Bowden,et al. Improving the visualization, interpretation and analysis of two-sample summary data Mendelian randomization via the Radial plot and Radial regression , 2018, International journal of epidemiology.
[6] Samuel E. Jones,et al. Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease , 2018, bioRxiv.
[7] Max A. Little,et al. GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates , 2018, bioRxiv.
[8] Samuel E. Jones,et al. Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour , 2018, bioRxiv.
[9] Valeriia Haberland,et al. The MR-Base platform supports systematic causal inference across the human phenome , 2018, eLife.
[10] Max A. Little,et al. Biological and clinical insights from genetics of insomnia symptoms , 2019, Nature Genetics.
[11] A I Pack,et al. Estimating sleep parameters using an accelerometer without sleep diary , 2018, Scientific Reports.
[12] Alex H. Wagner,et al. DGIdb 3.0: a redesign and expansion of the drug–gene interaction database , 2017, bioRxiv.
[13] D. A. Wellman,et al. Multiethnic Meta‐Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea‐related Quantitative Trait Locus in Men , 2017, American journal of respiratory cell and molecular biology.
[14] V. Salomaa,et al. Cohort Profile: The National FINRISK Study. , 2018, International journal of epidemiology.
[15] Erdogan Taskesen,et al. Functional mapping and annotation of genetic associations with FUMA , 2017, Nature Communications.
[16] Lars G Fritsche,et al. Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies , 2017, Nature Genetics.
[17] Stephen H. Bell,et al. Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry , 2022 .
[18] Lloyd T. Elliott,et al. The genetic basis of human brain structure and function: 1,262 genome-wide associations found from 3,144 GWAS of multimodal brain imaging phenotypes from 9,707 UK Biobank participants , 2017, bioRxiv.
[19] M. Perola,et al. Genetics of vaccination-related narcolepsy , 2017, bioRxiv.
[20] P. Donnelly,et al. Genome-wide genetic data on ~500,000 UK Biobank participants , 2017, bioRxiv.
[21] Jacob K. Asiedu,et al. The Drug Repurposing Hub: a next-generation drug library and information resource , 2017, Nature Medicine.
[22] E. Arrigoni,et al. Neural Circuitry of Wakefulness and Sleep , 2017, Neuron.
[23] Í. Berber,et al. Lack of association between MAOA-uVNTR variants and excessive daytime sleepiness , 2017, Neurological Sciences.
[24] Nils Y. Hammerla,et al. Large Scale Population Assessment of Physical Activity Using Wrist Worn Accelerometers: The UK Biobank Study , 2017, PloS one.
[25] S. Tsai. Chronic obstructive pulmonary disease and sleep related disorders , 2016, Current opinion in pulmonary medicine.
[26] Xiaofeng Zhu,et al. Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits , 2016, Nature Genetics.
[27] T. Spector,et al. Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. , 2016, Human molecular genetics.
[28] William J. Astle,et al. Allelic Landscape of Human Blood Cell Trait Variation and Links , 2016 .
[29] N. Sheehan,et al. Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic , 2016, International journal of epidemiology.
[30] Andres Metspalu,et al. Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci , 2016, PLoS genetics.
[31] Joseph K. Pickrell,et al. Detection and interpretation of shared genetic influences on 42 human traits , 2015, Nature Genetics.
[32] Andrew D. Rouillard,et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update , 2016, Nucleic Acids Res..
[33] Tom R. Gaunt,et al. LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis , 2016, bioRxiv.
[34] N. Eriksson,et al. GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person , 2016, Nature Communications.
[35] Daniel Marbach,et al. Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary Statistics , 2016, PLoS Comput. Biol..
[36] Y. Wada,et al. SLC39A8 Deficiency: A Disorder of Manganese Transport and Glycosylation. , 2015, American journal of human genetics.
[37] Michael Catt,et al. A Novel, Open Access Method to Assess Sleep Duration Using a Wrist-Worn Accelerometer , 2015, PloS one.
[38] J. Woo,et al. A Randomized Controlled Study to Examine the Effect of a Lifestyle Modification Program in OSA. , 2015, Chest.
[39] Yakir A Reshef,et al. Partitioning heritability by functional annotation using genome-wide association summary statistics , 2015, Nature Genetics.
[40] M. Daly,et al. An Atlas of Genetic Correlations across Human Diseases and Traits , 2015, Nature Genetics.
[41] A. Gloyn,et al. Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism , 2015, Current opinion in lipidology.
[42] Joris M. Mooij,et al. MAGMA: Generalized Gene-Set Analysis of GWAS Data , 2015, PLoS Comput. Biol..
[43] E. Bixler,et al. Natural history of excessive daytime sleepiness: role of obesity, weight loss, depression, and sleep propensity. , 2015, Sleep.
[44] G. Mensah,et al. NHLBI perspectives on the growth of heart, lung, blood and sleep conditions in Africa: global and domestic insights, challenges and opportunities , 2015, Cardiovascular journal of Africa.
[45] P. Elliott,et al. UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age , 2015, PLoS medicine.
[46] Carson C Chow,et al. Second-generation PLINK: rising to the challenge of larger and richer datasets , 2014, GigaScience.
[47] M. Daly,et al. Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants , 2014, Nature.
[48] B. Berger,et al. Efficient Bayesian mixed model analysis increases association power in large cohorts , 2014, Nature Genetics.
[49] J. J. Wang,et al. Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption , 2014, Molecular Psychiatry.
[50] T. Lallukka,et al. Sleep and sickness absence: a nationally representative register-based follow-up study. , 2014, Sleep.
[51] Joss Langford,et al. Autocalibration of accelerometer data for free-living physical activity assessment using local gravity and temperature: an evaluation on four continents , 2014, Journal of applied physiology.
[52] K. Rexrode,et al. Daytime sleepiness and risk of coronary heart disease and stroke: results from the Nurses' Health Study II. , 2014, Sleep medicine.
[53] A. Adan,et al. A functional polymorphism in the promoter region of MAOA gene is associated with daytime sleepiness in healthy subjects , 2014, Journal of the Neurological Sciences.
[54] J. Monti,et al. The role of serotonin 5-HT7 receptor in regulating sleep and wakefulness , 2014, Reviews in the neurosciences.
[55] D. Barford,et al. KSR2 Mutations Are Associated with Obesity, Insulin Resistance, and Impaired Cellular Fuel Oxidation , 2013, Cell.
[56] K. Hveem,et al. COHORT PROFILE Cohort Profile : The HUNT Study , Norway , 2013 .
[57] N. Wray,et al. A genome‐wide association study of sleep habits and insomnia , 2013, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[58] Ellen T. Gelfand,et al. The Genotype-Tissue Expression (GTEx) project , 2013, Nature Genetics.
[59] Alexander Horsch,et al. Separating Movement and Gravity Components in an Acceleration Signal and Implications for the Assessment of Human Daily Physical Activity , 2013, PloS one.
[60] E. Mignot,et al. Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia , 2013, PeerJ.
[61] Avi Ma'ayan,et al. Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool , 2013, BMC Bioinformatics.
[62] J. Wysocka,et al. Modification of enhancer chromatin: what, how, and why? , 2013, Molecular cell.
[63] C. Gieger,et al. ImmunoChip Study Implicates Antigen Presentation to T Cells in Narcolepsy , 2013, PLoS genetics.
[64] Jun Lu,et al. How do the basal ganglia regulate sleep–wake behavior? , 2012, Trends in Neurosciences.
[65] J. Steier,et al. Excessive daytime sleepiness in sleep disorders. , 2012, Journal of thoracic disease.
[66] Shambhu Bhat,et al. CACNA1C (Cav1.2) in the pathophysiology of psychiatric disease , 2012, Progress in Neurobiology.
[67] H. Jinnah,et al. Sleep Fragmentation and Motor Restlessness in a Drosophila Model of Restless Legs Syndrome , 2012, Current Biology.
[68] P. Visscher,et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits , 2012, Nature Genetics.
[69] Meena Kumari,et al. Sleep epidemiology--a rapidly growing field. , 2011, International journal of epidemiology.
[70] S. Thompson,et al. Bias in causal estimates from Mendelian randomization studies with weak instruments , 2011, Statistics in medicine.
[71] J. Duan,et al. Genome-wide approaches to schizophrenia , 2010, Brain Research Bulletin.
[72] Sebastiaan Overeem,et al. Genome-wide association study identifies new HLA class II haplotypes strongly protective against narcolepsy , 2010, Nature Genetics.
[73] G. Gigli,et al. Daytime sleepiness is associated with dementia and cognitive decline in older Italian adults: a population-based study. , 2010, Sleep medicine.
[74] C. McCrae,et al. Tackling sleeplessness: Psychological treatment options for insomnia , 2010, Nature and science of sleep.
[75] M. Qiu,et al. Basal ganglia control of sleep–wake behavior and cortical activation , 2010, The European journal of neuroscience.
[76] Daniel A. Cohen,et al. Uncovering Residual Effects of Chronic Sleep Loss on Human Performance , 2010, Science Translational Medicine.
[77] Robert E. Lewis,et al. KSR2 is an essential regulator of AMP kinase, energy expenditure, and insulin sensitivity. , 2009, Cell metabolism.
[78] C. Gieger,et al. Narcolepsy is strongly associated with the TCR alpha locus , 2009, Nature Genetics.
[79] [Sleep quality and daytime sleepiness in schizophrenia spectrum disorders during antipsychotic treatment]. , 2009, Psychiatria polska.
[80] Emmanuel Mignot,et al. Variant between CPT1B and CHKB associated with susceptibility to narcolepsy , 2008, Nature Genetics.
[81] M. Ohayon. From wakefulness to excessive sleepiness: what we know and still need to know. , 2008, Sleep medicine reviews.
[82] G. O'Connor,et al. Genome-wide association of sleep and circadian phenotypes , 2007, BMC Medical Genetics.
[83] Charles J. Bae,et al. The assessment, diagnosis, and treatment of excessive sleepiness: practical considerations for the psychiatrist. , 2007, Psychiatry (Edgmont (Pa. : Township)).
[84] D. Nutt. GABAA receptors: subtypes, regional distribution, and function. , 2006, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.
[85] E. Bixler,et al. Excessive daytime sleepiness in a general population sample: the role of sleep apnea, age, obesity, diabetes, and depression. , 2005, The Journal of clinical endocrinology and metabolism.
[86] D. Dinges,et al. Individual differences in adult human sleep and wakefulness: Leitmotif for a research agenda. , 2005, Sleep.
[87] D. Dinges,et al. Systematic interindividual differences in neurobehavioral impairment from sleep loss: evidence of trait-like differential vulnerability. , 2004, Sleep.
[88] Seppo Koskinen,et al. HEALTH AND FUNCTIONAL CAPACITY IN FINLAND Baseline Results of the Health 2000 Health Examination Survey , 2004 .
[89] M. Ohayon,et al. Daytime sleepiness and cognitive impairment in the elderly population. , 2002, Archives of internal medicine.
[90] P. Lloberes,et al. Self-reported sleepiness while driving as a risk factor for traffic accidents in patients with obstructive sleep apnoea syndrome and in non-apnoeic snorers. , 2000, Respiratory medicine.
[91] Emmanuel Mignot,et al. The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene , 1999, Cell.
[92] T. Roth,et al. Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults , 1996, Biological Psychiatry.
[93] D. Dijk,et al. Circadian and sleep/wake dependent aspects of subjective alertness and cognitive performance , 1992, Journal of sleep research.