The Impact of Hypergravity and Vibration on Gene and Protein Expression of Thyroid Cells

[1]  M. Braun,et al.  Alterations of the cytoskeleton in human cells in space proved by life-cell imaging , 2016, Scientific Reports.

[2]  Ruth Hemmersbach,et al.  Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity , 2015, Scientific Reports.

[3]  Albert Sickmann,et al.  Identification of proteins involved in inhibition of spheroid formation under microgravity , 2015, Proteomics.

[4]  Jens Hauslage,et al.  Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat , 2015, PloS one.

[5]  N. Hübner,et al.  Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers , 2015, Cell Communication and Signaling.

[6]  D. Grimm,et al.  Moderate alterations of the cytoskeleton in human chondrocytes after short‐term microgravity produced by parabolic flight maneuvers could be prevented by up‐regulation of BMP‐2 and SOX‐9 , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[7]  Y. Shan,et al.  Anti-apoptotic effects of osteopontin through the up-regulation of Mcl-1 in gastrointestinal stromal tumors , 2014, World Journal of Surgical Oncology.

[8]  M. Braun,et al.  Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1 , 2014, Cell Communication and Signaling.

[9]  Ruth Hemmersbach,et al.  Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[10]  J. Qin,et al.  Mechanisms of talin-dependent integrin signaling and crosstalk. , 2014, Biochimica et biophysica acta.

[11]  D. Grimm,et al.  Changes in Morphology, Gene Expression and Protein Content in Chondrocytes Cultured on a Random Positioning Machine , 2013, PloS one.

[12]  Astrid Horn,et al.  Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission. , 2013, Biomaterials.

[13]  P. Coulombe,et al.  Networking galore: intermediate filaments and cell migration. , 2013, Current opinion in cell biology.

[14]  R. Robinson,et al.  Guardians of the actin monomer. , 2013, European journal of cell biology.

[15]  D. Grimm,et al.  Interleukin-6 Expression under Gravitational Stress Due to Vibration and Hypergravity in Follicular Thyroid Cancer Cells , 2013, PloS one.

[16]  P. Roy,et al.  Profilin-1 versus profilin-2: two faces of the same coin? , 2013, Breast Cancer Research.

[17]  M. Braun,et al.  The Impact of Altered Gravity and Vibration on Endothelial Cells During a Parabolic Flight , 2013, Cellular Physiology and Biochemistry.

[18]  A. Sickmann,et al.  Interaction of Proteins Identified in Human Thyroid Cells , 2013, International journal of molecular sciences.

[19]  Ruth Hemmersbach,et al.  Gravity‐sensitive signaling drives 3‐dimensional formation of multicellular thyroid cancer spheroids , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[20]  Scott D. Hansen,et al.  Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion. , 2012, Cancer cell.

[21]  P. Zancan,et al.  AMP-activated protein kinase upregulates glucose uptake in thyroid PCCL3 cells independent of thyrotropin. , 2012, Thyroid : official journal of the American Thyroid Association.

[22]  B. Wehrle-Haller Assembly and disassembly of cell matrix adhesions. , 2012, Current opinion in cell biology.

[23]  L. Young,et al.  AMP-Activated Protein Kinase Regulation and Biological Actions in the Heart , 2012, Circulation research.

[24]  R. Wildgruber,et al.  Metabolic enzyme diversity in different human thyroid cell lines and their sensitivity to gravitational forces , 2012, Proteomics.

[25]  M. Pelizzo,et al.  Protein kinase C: a putative new target for the control of human medullary thyroid carcinoma cell proliferation in vitro. , 2012, Endocrinology.

[26]  M. Ginsberg,et al.  Regulation of integrin activation. , 2011, Annual review of cell and developmental biology.

[27]  M. Pang,et al.  The effects of whole body vibration therapy on bone mineral density and leg muscle strength in older adults: a systematic review and meta-analysis , 2011, Clinical rehabilitation.

[28]  R. Einspanier,et al.  Differential Gene Regulation under Altered Gravity Conditions in Follicular Thyroid Cancer Cells: Relationship between the Extracellular Matrix and the Cytoskeleton , 2011, Cellular Physiology and Biochemistry.

[29]  R. Fehon,et al.  Ezrin, Radixin and Moesin: key regulators of membrane-cortex interactions and signaling. , 2011, Current opinion in cell biology.

[30]  D. Grimm,et al.  The effects of weightlessness on the human organism and mammalian cells. , 2011, Current molecular medicine.

[31]  R. Wildgruber,et al.  A proteomic approach to analysing spheroid formation of two human thyroid cell lines cultured on a random positioning machine , 2011, Proteomics.

[32]  Lei Cui,et al.  CTGF is overexpressed in papillary thyroid carcinoma and promotes the growth of papillary thyroid cancer cells , 2011, Tumor Biology.

[33]  F. Curcio,et al.  Thyrotropin receptor and membrane interactions in FRTL-5 thyroid cell strain in microgravity. , 2011, Astrobiology.

[34]  D. Grimm,et al.  How and why does the proteome respond to microgravity? , 2011, Expert review of proteomics.

[35]  J. Colicelli,et al.  ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity , 2010, Science Signaling.

[36]  J. Ervasti,et al.  The Actin Gene Family: Function Follows Isoform , 2010, Cytoskeleton.

[37]  Marie-France Carlier,et al.  Control of actin filament treadmilling in cell motility. , 2010, Annual review of biophysics.

[38]  Wei Liu,et al.  Osteopontin (OPN) expression in thyroid carcinoma. , 2010, Anticancer research.

[39]  Kriss Westphal,et al.  Characterization of Human Chondrocytes Exposed to Simulated Microgravity , 2010, Cellular Physiology and Biochemistry.

[40]  R. Wildgruber,et al.  Application of free‐flow IEF to identify protein candidates changing under microgravity conditions , 2010, Proteomics.

[41]  D. Grimm,et al.  Different responsiveness of endothelial cells to vascular endothelial growth factor and basic fibroblast growth factor added to culture media under gravity and simulated microgravity. , 2010, Tissue engineering. Part A.

[42]  R. Layfield,et al.  Annexins in human breast cancer: Possible predictors of pathological response to neoadjuvant chemotherapy. , 2009, European journal of cancer.

[43]  Kriss Westphal,et al.  A delayed type of three-dimensional growth of human endothelial cells under simulated weightlessness. , 2009, Tissue engineering. Part A.

[44]  R. Perego,et al.  Eight full‐length abelson related gene (Arg) isoforms are constitutively expressed in caki‐1 cell line and cell distribution of two isoforms has been analyzed after transfection , 2008, Journal of cellular biochemistry.

[45]  E. Prakash,et al.  Connective tissue growth factor (CTGF) and cancer progression. , 2008, Journal of biomedical science.

[46]  Augusto Cogoli,et al.  Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity , 2008, Journal of cellular biochemistry.

[47]  A. Bhardwaj,et al.  Intracellular Versican Expression in Mesenchymal Spindle Cell Tumors Contrasts With Extracellular Expression in Epithelial and Other Tumors—A Tissue Microarray-based Study , 2008, Applied immunohistochemistry & molecular morphology : AIMM.

[48]  D. Grimm,et al.  Expression of vascular endothelial growth factor and receptor tyrosine kinases in cardiac ischemia/reperfusion injury. , 2007, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

[49]  Johanna Ivaska,et al.  Novel functions of vimentin in cell adhesion, migration, and signaling. , 2007, Experimental cell research.

[50]  E. Lane,et al.  Intermediate filaments and stress. , 2007, Experimental cell research.

[51]  Y. Okada,et al.  ADAMs in cancer cell proliferation and progression , 2007, Cancer science.

[52]  E. Hohenester,et al.  Mammalian collagen receptors. , 2007, Matrix biology : journal of the International Society for Matrix Biology.

[53]  M. Shakibaei,et al.  Induction of three-dimensional assembly and increase in apoptosis of human endothelial cells by simulated microgravity: Impact of vascular endothelial growth factor , 2006, Apoptosis.

[54]  M. Santoro,et al.  Osteopontin is overexpressed in human papillary thyroid carcinomas and enhances thyroid carcinoma cell invasiveness. , 2005, The Journal of clinical endocrinology and metabolism.

[55]  G. Schulze-Tanzil,et al.  Weightlessness induced apoptosis in normal thyroid cells and papillary thyroid carcinoma cells via extrinsic and intrinsic pathways. , 2003, Endocrinology.

[56]  T. Pollard The cytoskeleton, cellular motility and the reductionist agenda , 2003, Nature.

[57]  Thomas D Pollard,et al.  Cellular Motility Driven by Assembly and Disassembly of Actin Filaments , 2003, Cell.

[58]  G. Schulze-Tanzil,et al.  Early onset of chondroitin sulfate and osteopontin expression in angiotensin II-dependent left ventricular hypertrophy. , 2002, American journal of hypertension.

[59]  G. Schulze-Tanzil,et al.  Low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin increase transforming growth factor β and cause myocardial fibrosis in marmosets (Callithrix jacchus) , 2002, Archives of Toxicology.

[60]  G. Schulze-Tanzil,et al.  Simulated microgravity alters differentiation and increases apoptosis in human follicular thyroid carcinoma cells , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[61]  R. Locksley,et al.  The TNF and TNF Receptor Superfamilies Integrating Mammalian Biology , 2001, Cell.

[62]  T. Davies,et al.  Thyroid organoid formation in simulated microgravity: influence of keratinocyte growth factor. , 2000, Thyroid : official journal of the American Thyroid Association.

[63]  R. Hemmersbach,et al.  Response to thyrotropin of normal thyroid follicular cell strain FRTL5 in hypergravity. , 1999, Biochimie.

[64]  Marian L. Lewis,et al.  Spaceflight alters microtubules and increases apoptosis in human lymphocytes (Jurkat) , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[65]  W. Schmidt Quickly changing acceleration forces (QCAFs) vibration analysis on the A300 ZERO-G , 2004, Microgravity science and technology.

[66]  T. Pollard,et al.  Cellular Motility Driven by Assembly and Disassembly of Actin Filaments , 2003, Cell.

[67]  D. Gullberg,et al.  Collagen-binding I domain integrins--what do they do? , 2002, Progress in histochemistry and cytochemistry.

[68]  C. Morris,et al.  The integrin alpha10 subunit: expression pattern, partial gene structure, and chromosomal localization. , 1999, Cytogenetics and cell genetics.

[69]  F. Curcio,et al.  Response to hypogravity of normal in vitro cultured follicular cells from thyroid. , 1998, Acta astronautica.

[70]  D. Hardie,et al.  The AMP-activated protein kinase--fuel gauge of the mammalian cell? , 1997, European journal of biochemistry.