MicroRNA-Mediated Downregulation of the Potassium Channel Kv4.2 Contributes to Seizure Onset.
暂无分享,去创建一个
S. Danzer | E. Jimenez-Mateos | D. Henshall | L. Xing | C. Gross | G. Bassell | T. Engel | R. Pun | Xiaodi Yao | Shane D. Rowley | Scott W. Danielson | Lindsay M. Schroeder | Kristen T. Thomas | Durgesh Tiwari
[1] I. Bozzoni,et al. microRNAs Modulate Spatial Memory in the Hippocampus and in the Ventral Striatum in a Region-Specific Manner , 2016, Molecular Neurobiology.
[2] Chaoqian Xu,et al. MiR-223-3p as a Novel MicroRNA Regulator of Expression of Voltage-Gated K+ Channel Kv4.2 in Acute Myocardial Infarction , 2016, Cellular Physiology and Biochemistry.
[3] T. Baram,et al. Dual and Opposing Roles of MicroRNA-124 in Epilepsy Are Mediated through Inflammatory and NRSF-Dependent Gene Networks. , 2016, Cell reports.
[4] D. Johnston,et al. Cell-Type Specific Channelopathies in the Prefrontal Cortex of the fmr1-/y Mouse Model of Fragile X Syndrome,, , 2015, eNeuro.
[5] D. Bartel,et al. Predicting effective microRNA target sites in mammalian mRNAs , 2015, eLife.
[6] Z. Xu,et al. Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats , 2014, Journal of neuroscience research.
[7] H. Fröhlich,et al. Different MicroRNA Profiles in Chronic Epilepsy Versus Acute Seizure Mouse Models , 2014, Journal of Molecular Neuroscience.
[8] S. Nelson,et al. Exome sequencing identifies de novo gain of function missense mutation in KCND2 in identical twins with autism and seizures that slows potassium channel inactivation. , 2014, Human molecular genetics.
[9] D. Johnston,et al. Loss of Functional A-Type Potassium Channels in the Dendrites of CA1 Pyramidal Neurons from a Mouse Model of Fragile X Syndrome , 2013, The Journal of Neuroscience.
[10] J. Cuevas,et al. MicroRNA-301a Mediated Regulation of Kv4.2 in Diabetes: Identification of Key Modulators , 2013, PloS one.
[11] J. Prehn,et al. Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell death , 2013, Cell Death and Disease.
[12] S. D. Moore,et al. The Auxiliary Subunit KChIP2 Is an Essential Regulator of Homeostatic Excitability* , 2013, The Journal of Biological Chemistry.
[13] Donncha F. O’Brien,et al. Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects , 2012, Nature Medicine.
[14] A. Pasquinelli. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship , 2012, Nature Reviews Genetics.
[15] Z. Xu,et al. Alterations of A-type potassium channels in hippocampal neurons after traumatic brain injury. , 2012, Journal of neurotrauma.
[16] Y. Jan,et al. Bidirectional Regulation of Dendritic Voltage-Gated Potassium Channels by the Fragile X Mental Retardation Protein , 2011, Neuron.
[17] R. Stallings,et al. miRNA Expression profile after status epilepticus and hippocampal neuroprotection by targeting miR-132. , 2011, The American journal of pathology.
[18] D. Hoffman,et al. DPP6 Establishes the A-Type K+ Current Gradient Critical for the Regulation of Dendritic Excitability in CA1 Hippocampal Neurons , 2011, Neuron.
[19] S. Warren,et al. Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling. , 2011, Molecular cell.
[20] Yan Cheng,et al. Temporal lobe epilepsy induces differential expression of hippocampal miRNAs including let-7e and miR-23a/b , 2011, Brain Research.
[21] A. Jeromin,et al. Fragile X Mental Retardation Protein Regulates Protein Expression and mRNA Translation of the Potassium Channel Kv4.2 , 2011, The Journal of Neuroscience.
[22] J. Neilson,et al. Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132 , 2010, Neuron.
[23] R. Hrachovy,et al. Kv4.2 knockout mice demonstrate increased susceptibility to convulsant stimulation , 2009, Epilepsia.
[24] D. Bartel. MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.
[25] K. Rhodes,et al. Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy , 2008, Neuroscience.
[26] Sasha F. Levy,et al. Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR. , 2007, RNA.
[27] Daniel Johnston,et al. Deletion of Kv4.2 Gene Eliminates Dendritic A-Type K+ Current and Enhances Induction of Long-Term Potentiation in Hippocampal CA1 Pyramidal Neurons , 2006, The Journal of Neuroscience.
[28] Kazumi Matsuda,et al. A Kv4.2 truncation mutation in a patient with temporal lobe epilepsy , 2006, Neurobiology of Disease.
[29] J. Nerbonne,et al. Targeted Deletion of Kv4.2 Eliminates Ito,f and Results in Electrical and Molecular Remodeling, With No Evidence of Ventricular Hypertrophy or Myocardial Dysfunction , 2005, Circulation research.
[30] M. Covarrubias,et al. Molecular physiology and modulation of somatodendritic A-type potassium channels , 2004, Molecular and Cellular Neuroscience.
[31] D. Johnston,et al. Acquired Dendritic Channelopathy in Temporal Lobe Epilepsy , 2004, Science.
[32] Daniela C. Zarnescu,et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway , 2004, Nature Neuroscience.
[33] Gary Ruvkun,et al. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[34] K. Rhodes,et al. A Fundamental Role for KChIPs in Determining the Molecular Properties and Trafficking of Kv4.2 Potassium Channels* , 2003, Journal of Biological Chemistry.
[35] J. Eubanks,et al. Kainic acid-induced generalized seizures alter the regional hippocampal expression of the rat Kv4.2 potassium channel gene , 1997, Neuroscience Letters.
[36] Y. Jan,et al. Differential expression of K+ channel mRNAs in the rat brain and down-regulation in the hippocampus following seizures , 1992, Neuron.
[37] D. Henshall,et al. microRNA and Epilepsy. , 2015, Advances in experimental medicine and biology.
[38] Sébastien A. Gauthier,et al. In vitro assays measuring protection by proteins such as cystatin C of primary cortical neuronal and smooth muscle cells. , 2012, Methods in molecular biology.