Targeting the forgotten transglycosylases.
暂无分享,去创建一个
Judy Halliday | Wim Meutermans | W. Meutermans | P. Rajaratnam | J. Halliday | Craig Muldoon | Declan McKeveney | Premraj Rajaratnam | D. McKeveney | C. Muldoon | Declan McKeveney
[1] G. Huber,et al. Moenomycin, an inhibitor of cell wall synthesis. , 1968, Biochemical and biophysical research communications.
[2] S. Hentschel,et al. [Staphylococcus aureus in poultry--biochemical characteristics, antibiotic resistance and phage pattern (author's transl)]. , 1979, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe B: Hygiene, Betriebshygiene, praventive Medizin.
[3] S. Tamaki,et al. Functional biosynthesis of cell wall peptidoglycan by polymorphic bifunctional polypeptides. Penicillin-binding protein 1Bs of Escherichia coli with activities of transglycosylase and transpeptidase. , 1984, The Journal of biological chemistry.
[4] B. Spratt,et al. Lysis of Escherichia coli by beta-lactam antibiotics: deletion analysis of the role of penicillin-binding proteins 1A and 1B. , 1985, Journal of general microbiology.
[5] J. van Heijenoort,et al. Effects of moenomycin on Escherichia coli. , 1987, Journal of general microbiology.
[6] Frithjof Kruggel,et al. Moenomycin a: Minimum structural requirements for biological activity , 1987 .
[7] W. Dietrich,et al. Synthesis of two structural analogues of the smallest antibiotically active degradation product of moenomycin a , 1988 .
[8] J. Heijenoort,et al. Moenomycin A: A structural revision and new structure-activity reactions , 1990 .
[9] K. Lackey,et al. Synthesis of compounds designed to inhibit bacterial cell wall transglycosylation , 1990 .
[10] J. Heijenoort,et al. The first enzymatic degradation products of the antibiotic moenomycin A. , 1992 .
[11] J. Heijenoort,et al. Structures of some moenomycin antibiotics - inhibitors of peptidoglycan biosynthesis , 1993 .
[12] M. Arthur,et al. Genetics and mechanisms of glycopeptide resistance in enterococci , 1993, Antimicrobial Agents and Chemotherapy.
[13] P. Welzel,et al. Moenomycin A - Structure-activity relations synthesis of the D-galacturonamide analogue of the smallest antibiotically active degradation product of moenomycin A , 1993 .
[14] J. Heijenoort,et al. The first synthesis of a moenomycin-type transglycosylase inhibitor , 1993 .
[15] C. Walsh,et al. Vancomycin resistance: decoding the molecular logic. , 1993, Science.
[16] J. Heijenoort,et al. Moenomycin A: reactions at the lipid part. New structure-activity relations , 1994 .
[17] R. Southgate,et al. Synthesis of derivatives of muramic acid and C-1 homologated α-D-glucose as potential inhibitors of bacterial transglycosylase , 1995 .
[18] B. M. Pinto,et al. Application of two-dimensional NMR spectroscopy and molecular dynamics simulations to the conformational analysis of oligosaccharides corresponding to the cell-wall polysaccharide of Streptococcus group A. , 1995, International journal of biological macromolecules.
[19] J. Heijenoort,et al. Introduction of a terminal hydroxy group into the lipid part of a moenomycin-type transglycosylase inhibitor suppresses antibiotic activity , 1995 .
[20] C. Walsh,et al. Bacterial resistance to vancomycin: five genes and one missing hydrogen bond tell the story. , 1996, Chemistry & biology.
[21] T. Nicas,et al. Structural modifications of glycopeptide antibiotics , 1997, Medicinal research reviews.
[22] H. Sahl,et al. The lantibiotic mersacidin inhibits peptidoglycan biosynthesis at the level of transglycosylation. , 1997, European journal of biochemistry.
[23] J. Heijenoort,et al. A chemoenzymatic approach towards moenomycin structural analogues , 1997 .
[24] J. Heijenoort,et al. Synthesis of a trisaccharide analogue of moenomycin A12 Implications of new moenomycin structure-activity relationships , 1997 .
[25] D. Jendrossek,et al. A putative monofunctional glycosyltransferase is expressed in Ralstonia eutropha , 1997, Journal of bacteriology.
[26] H. Sahl,et al. Role of lipid‐bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics , 1998, Molecular microbiology.
[27] T. Vernet,et al. Identification, Purification, and Characterization of Transpeptidase and Glycosyltransferase Domains of Streptococcus pneumoniae Penicillin-Binding Protein 1a , 1998, Journal of bacteriology.
[28] J. Ghuysen,et al. Multimodular Penicillin-Binding Proteins: An Enigmatic Family of Orthologs and Paralogs , 1998, Microbiology and Molecular Biology Reviews.
[29] W. Aretz,et al. Exploratory investigations into the biosynthesis of the antibiotic moenomycin A , 1998 .
[30] H. Sahl,et al. The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II , 1998, Antimicrobial Agents and Chemotherapy.
[31] J. Ghuysen,et al. The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan‐polymerizing penicillin‐binding protein 1b of Escherichia coli , 1999, Molecular microbiology.
[32] R. Lurz,et al. Mutational Analysis of the Streptococcus pneumoniae Bimodular Class A Penicillin-Binding Proteins , 1999, Journal of bacteriology.
[33] J. Heijenoort,et al. Acceptor site recognition of transglycosylase inhibitors a β-D-glucopyranosyl-(1→2)-α-D-glucopyranuronamide-derived moenomycin analogue , 1999 .
[34] Zhong Chen,et al. Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala. , 1999, Science.
[35] J. Heijenoort,et al. Synthesis and transglycosylase-inhibiting properties of a disaccharide analogue of moenomycin A lacking substitution at C-4 of unit F , 1999 .
[36] Peter Welzel,et al. Moenomycin A: The role of the methyl group in the moenuronamide unit and a general discussion of structure-activity relationships , 1999 .
[37] T. Bugg. 3.10 – Bacterial Peptidoglycan Biosynthesis and its Inhibition , 1999 .
[38] F. Chi,et al. Discovery of novel disaccharide antibacterial agents using a combinatorial library approach. , 1999, Journal of medicinal chemistry.
[39] A. Branstrom,et al. Chlorobiphenyl-desleucyl-vancomycin inhibits the transglycosylation process required for peptidoglycan synthesis in bacteria in the absence of dipeptide binding. , 2000, FEMS microbiology letters.
[40] K. Richter,et al. Some selective reactions of moenomycin A. , 2000, Bioorganic & medicinal chemistry letters.
[41] F. Haesebrouck,et al. Influence of different medium components on the in vitro activity of the growth-promoting antibiotic flavomycin against enterococci. , 2000, The Journal of antimicrobial chemotherapy.
[42] R C Goldman,et al. Inhibition of transglycosylation involved in bacterial peptidoglycan synthesis. , 2000, Current medicinal chemistry.
[43] Peter Welzel,et al. Moenomycin analogues with long-chain amine lipid parts from reductive aminations , 2001 .
[44] J. Markwalder,et al. Lipid II: total synthesis of the bacterial cell wall precursor and utilization as a substrate for glycosyltransfer and transpeptidation by penicillin binding protein (PBP) 1b of Escherichia coli. , 2001, Journal of the American Chemical Society.
[45] D. Kahne,et al. Hybrid glycopeptide antibiotics. , 2001, Journal of the American Chemical Society.
[46] Patrick Butaye,et al. Differences in Antibiotic Resistance Patterns ofEnterococcus faecalis and Enterococcus faeciumStrains Isolated from Farm and Pet Animals , 2001, Antimicrobial Agents and Chemotherapy.
[47] Q. Wang,et al. Identification and Characterization of a Monofunctional Glycosyltransferase from Staphylococcus aureus , 2001, Journal of bacteriology.
[48] I. Pelczer,et al. A new structure for the substrate-binding antibiotic ramoplanin. , 2001, Journal of the American Chemical Society.
[49] J. Heijenoort. Formation of the glycan chains in the synthesis of bacterial peptidoglycan , 2001 .
[50] S. Vogel,et al. Moenomycin analogues with modified lipid side chains from indium-mediated Barbier-type reactions , 2001 .
[51] P. Griffin,et al. Direct interaction of a vancomycin derivative with bacterial enzymes involved in cell wall biosynthesis. , 2001, Chemistry & biology.
[52] R. Kruger,et al. Chemistry and biology of the ramoplanin family of peptide antibiotics. , 2002, Biopolymers.
[53] Robert Kaptein,et al. Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles. , 2002, Biochemistry.
[54] M. Findeisen,et al. Synthesis of analogues of the 2-O-alkyl glycerate part of the moenomycins , 2002 .
[55] E. Stobberingh,et al. Effects of Flavophospholipol on Resistance in Fecal Escherichia coli and Enterococci of Fattening P , 2002, Antimicrobial Agents and Chemotherapy.
[56] B. de Kruijff,et al. Lipid II induces a transmembrane orientation of the pore-forming peptide lantibiotic nisin. , 2002, Biochemistry.
[57] A. Wand,et al. Functional analysis of the lipoglycodepsipeptide antibiotic ramoplanin. , 2002, Chemistry & biology.
[58] A. Wand,et al. Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: Minimal structural requirements for intermolecular complexation and fibril formation , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[59] J. Ayala,et al. A Surface Plasmon Resonance Analysis of the Interaction between the Antibiotic Moenomycin A and Penicillin‐Binding Protein 1b , 2002 .
[60] M. VanNieuwenhze,et al. The first total synthesis of lipid II: the final monomeric intermediate in bacterial cell wall biosynthesis. , 2002, Journal of the American Chemical Society.
[61] R. Williamson,et al. Mannopeptimycins, novel antibacterial glycopeptides from Streptomyces hygroscopicus, LL-AC98. , 2002, Journal of the American Chemical Society.
[62] Nancy Torres,et al. Synthesis and evaluation of ether and halogenated derivatives of mannopeptimycin glycopeptide antibiotics. , 2003, Bioorganic & medicinal chemistry letters.
[63] D. Popham,et al. Peptidoglycan Synthesis in the Absence of Class A Penicillin-Binding Proteins in Bacillus subtilis , 2003, Journal of bacteriology.
[64] S. Walker,et al. Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II. , 2003, Journal of the American Chemical Society.
[65] T. Vernet,et al. The Glycosyltransferase Domain of Penicillin-Binding Protein 2a from Streptococcus pneumoniae Catalyzes the Polymerization of Murein Glycan Chains , 2003, Journal of bacteriology.
[66] T. Vernet,et al. Functional Characterization of Penicillin-Binding Protein 1b from Streptococcus pneumoniae , 2003, Journal of bacteriology.
[67] M. Preobrazhenskaya,et al. Role of the glycopeptide framework in the antibacterial activity of hydrophobic derivatives of glycopeptide antibiotics. , 2003, Journal of medicinal chemistry.
[68] J. Judice,et al. Semi-synthetic glycopeptide antibacterials. , 2003, Bioorganic & medicinal chemistry letters.
[69] T. Nicas,et al. Mechanism of action of oritavancin and related glycopeptide antibiotics. , 2003, FEMS microbiology reviews.
[70] D. Volke,et al. Studies on the interaction of the antibiotic moenomycin A with the enzyme penicillin-binding protein 1b. , 2003, Bioorganic & medicinal chemistry.
[71] S. Walker,et al. Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[72] P. Bradford,et al. Mannopeptimycins, New Cyclic Glycopeptide Antibiotics Produced by Streptomyces hygroscopicus LL-AC98: Antibacterial and Mechanistic Activities , 2003, Antimicrobial Agents and Chemotherapy.
[73] R. Kaptein,et al. NMR Study of Mersacidin and Lipid II Interaction in Dodecylphosphocholine Micelles , 2003, The Journal of Biological Chemistry.
[74] A. Heck,et al. Lipid II Is an Intrinsic Component of the Pore Induced by Nisin in Bacterial Membranes* , 2003, Journal of Biological Chemistry.
[75] Nancy Torres,et al. Novel ether derivatives of mannopeptimycin glycopeptide antibiotic. , 2003, Bioorganic & medicinal chemistry letters.
[76] R. Shandil,et al. High-Throughput Screen for Inhibitors of Transglycosylase and/or Transpeptidase Activities of Escherichia coli Penicillin Binding Protein 1b , 2004, Antimicrobial Agents and Chemotherapy.
[77] J. Vederas,et al. Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b. , 2004, Bioorganic & medicinal chemistry.
[78] J. Vederas,et al. Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity. , 2004, Biochemistry.
[79] P. Bradford,et al. Mechanism of Action of the Mannopeptimycins, a Novel Class of Glycopeptide Antibiotics Active against Vancomycin-Resistant Gram-Positive Bacteria , 2004, Antimicrobial Agents and Chemotherapy.
[80] D. Boger,et al. Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics. , 2004, Journal of the American Chemical Society.
[81] F. Bambeke. Glycopeptides in clinical development: pharmacological profile and clinical perspectives. , 2004 .
[82] S. Lang,et al. Hydrophobic acetal and ketal derivatives of mannopeptimycin-alpha and desmethylhexahydromannopeptimycin-alpha: semisynthetic glycopeptides with potent activity against Gram-positive bacteria. , 2004, Journal of medicinal chemistry.
[83] B. de Kruijff,et al. Assembly and stability of nisin-lipid II pores. , 2004, Biochemistry.
[84] Hai-yin He. Mannopeptimycins, a novel class of glycopeptide antibiotics active against gram-positive bacteria , 2005, Applied Microbiology and Biotechnology.
[85] In Vivo Efficacy and Pharmacokinetics of AC98-6446, a Novel Cyclic Glycopeptide, in Experimental Infection Models , 2004, Antimicrobial Agents and Chemotherapy.
[86] M. Findeisen,et al. Studies on the Synthesis of Di- and Trisaccharide Analogues of Moenomycin A. Modifications in Unit E and in the Lipid Part , 2004 .
[87] M. Findeisen,et al. Studies on the Synthesis of Trisaccharide Analogues of the Antibiotic Moenomycin A , 2004 .
[88] F. Koehn,et al. Mannopeptimycin esters and carbonates, potent antibiotic agents against drug-resistant bacteria. , 2004, Bioorganic & medicinal chemistry letters.
[89] D. Guay. Oritavancin and Tigecycline: Investigational Antimicrobials for Multidrug‐Resistant Bacteria , 2004, Pharmacotherapy.
[90] D. Mengin-Lecreulx,et al. Role of Class A Penicillin-Binding Proteins in PBP5-Mediated β-Lactam Resistance in Enterococcus faecalis , 2004, Journal of bacteriology.
[91] P. Bradford,et al. Comparative In Vitro Activities of AC98-6446, a Novel Semisynthetic Glycopeptide Derivative of the Natural Product Mannopeptimycin α, and Other Antimicrobial Agents against Gram-Positive Clinical Isolates , 2004, Antimicrobial Agents and Chemotherapy.
[92] S. Walker,et al. Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. , 2005, Journal of the American Chemical Society.
[93] Otto Dideberg,et al. Active site restructuring regulates ligand recognition in class A penicillin-binding proteins. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[94] C. Walsh,et al. Glycopeptide and lipoglycopeptide antibiotics. , 2005, Chemical reviews.
[95] R. Jones,et al. Antimicrobial activity of dalbavancin tested against Gram-positive clinical isolates from Latin American medical centres. , 2005, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.
[96] J. Barrett. Recent developments in glycopeptide antibacterials. , 2005, Current opinion in investigational drugs.
[97] S. Walker,et al. Kinetic Characterization of the Glycosyltransferase Module of Staphylococcus aureus PBP2 , 2005, Journal of bacteriology.
[98] D. Boger,et al. Chemistry and biology of ramoplanin: a lipoglycodepsipeptide with potent antibiotic activity. , 2005, Chemical reviews.