This paper deals with cargo security and its optimization as a result of transport experiments. It also statistically evaluates these transport experiments with its emphasis on local extremes (accelerations) and compares the result of each day’s measurements. The article includes a model of cargo security on a medium size off-road T-810 6 × 6 truck, where the measured data was applied for logistics purposes. The completed transport experiment points to larger inertial forces during transport than predicted, based on the set of normative acceleration coefficient values. Although the results of the experiment show that the highest measured value of the coefficient of acceleration is 3 times greater than the normatively determined, we found the value to actually be 3.4 times higher than predicted, using the standard values. Due to the not inconsiderable percentage values which exceed the specified values of normatively set coefficients of acceleration (10.83%, respectively 13.31%) exceeding the set values of inertia forces can be expected in these cases as well.