Timing of growth hormone treatment affects trabecular bone microarchitecture and mineralization in growth hormone deficient mice.

[1]  Olivier Guyen,et al.  Contribution of Trabecular and Cortical Components to Biomechanical Behavior of Human Vertebrae: An Ex Vivo Study , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[2]  Steven K Boyd,et al.  Reproducibility of bone micro-architecture measurements in rodents by in vivo micro-computed tomography is maximized with three-dimensional image registration. , 2010, Bone.

[3]  F. Maes,et al.  Effect of in vivo micro-CT radiation on trabecular bone morphology in mice , 2009 .

[4]  E. Krenning,et al.  Bone Mineral Density and Body Composition in Adolescents with Childhood-Onset Growth Hormone Deficiency , 2009, Hormone Research in Paediatrics.

[5]  Steven K Boyd,et al.  Postpubertal Architectural Developmental Patterns Differ Between the L3 Vertebra and Proximal Tibia in Three Inbred Strains of Mice , 2008, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[6]  Steven K Boyd,et al.  Radiation effects on bone architecture in mice and rats resulting from in vivo micro-computed tomography scanning. , 2008, Medical engineering & physics.

[7]  G. Binder,et al.  Similar effects of long-term exogenous growth hormone (GH) on bone and muscle parameters: a pQCT study of GH-deficient and small-for-gestational-age (SGA) children. , 2007, Bone.

[8]  Rik Huiskes,et al.  No effects of in vivo micro‐CT radiation on structural parameters and bone marrow cells in proximal tibia of wistar rats detected after eight weekly scans , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[9]  S. Judex,et al.  Accretion of Bone Quantity and Quality in the Developing Mouse Skeleton , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[10]  Harrie Weinans,et al.  Effects of microarchitecture on bone strength , 2007, Current osteoporosis reports.

[11]  R. Murray,et al.  A densitometric and morphometric analysis of the skeleton in adults with varying degrees of growth hormone deficiency. , 2006, The Journal of clinical endocrinology and metabolism.

[12]  J. T. ter Maaten,et al.  Effect of Long‐Term Growth Hormone Treatment on Bone Mass and Bone Metabolism in Growth Hormone‐Deficient Men , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[13]  R. Bouillon,et al.  Bone status and fracture prevalence in Russian adults with childhood-onset growth hormone deficiency. , 2004, The Journal of clinical endocrinology and metabolism.

[14]  G. Binder,et al.  Cortical bone density is normal in prepubertal children with growth hormone (GH) deficiency, but initially decreases during GH replacement due to early bone remodeling. , 2004, The Journal of clinical endocrinology and metabolism.

[15]  H. Delemarre-van de Waal,et al.  GH treatment and its effect on bone mineral density, bone maturation and growth in short children born small for gestational age: 3‐year results of a randomized, controlled GH trial , 2003, Clinical endocrinology.

[16]  S. Mohan,et al.  Evidence that sensitivity to growth hormone (GH) is growth period and tissue type dependent: studies in GH-deficient lit/lit mice. , 2003, Endocrinology.

[17]  L. Donahue,et al.  Insulin-like growth factor regulates peak bone mineral density in mice by both growth hormone-dependent and -independent mechanisms. , 2003, Endocrinology.

[18]  George P Chrousos,et al.  Positive Linear Growth and Bone Responses to Growth Hormone Treatment in Children With Types III and IV Osteogenesis Imperfecta: High Predictive Value of the Carboxyterminal Propeptide of Type I Procollagen , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[19]  W. Hop,et al.  Long-Term Effects of Growth Hormone Therapy on Bone Mineral Density, Body Composition, and Serum Lipid Levels in Growth Hormone Deficient Children: A 6-Year Follow-Up Study , 2002, Hormone Research in Paediatrics.

[20]  X. Guo,et al.  Mechanical consequence of trabecular bone loss and its treatment: a three-dimensional model simulation. , 2002, Bone.

[21]  Kay Dickersin,et al.  Osteoporosis prevention, diagnosis, and therapy. , 2000, NIH consensus statement.

[22]  A. Bartke,et al.  Deficits in female reproductive function in GH-R-KO mice; role of IGF-I. , 1999, Endocrinology.

[23]  L. Mosekilde,et al.  Growth hormone increases vertebral and femoral bone strength in osteopenic, ovariectomized, aged rats in a dose-dependent and site-specific manner. , 1998, Bone.

[24]  B. Brennan,et al.  The diagnosis of growth hormone deficiency in children and adults. , 1998, Endocrine reviews.

[25]  J. Aloia,et al.  Histologic evidence: Growth hormone completely prevents reduction in cortical bone gain and partially prevents cancellous osteopenia in the tibia of hypophysectomized rats , 1997, The Anatomical record.

[26]  J. Flier,et al.  Leptin accelerates the onset of puberty in normal female mice. , 1997, The Journal of clinical investigation.

[27]  G. Saggese,et al.  The effect of long-term growth hormone (GH) treatment on bone mineral density in children with GH deficiency. Role of GH in the attainment of peak bone mass. , 1996, The Journal of clinical endocrinology and metabolism.

[28]  P. Lips,et al.  Histomorphometric analysis of bone mass and bone metabolism in growth hormone deficient adult men. , 1996, Bone.

[29]  D. Harris,et al.  Utah Growth Study: growth standards and the prevalence of growth hormone deficiency. , 1994, The Journal of pediatrics.

[30]  J. Tobias,et al.  Growth hormone deficiency during puberty reduces adult bone mineral density. , 1992, Archives of disease in childhood.

[31]  D R Carter,et al.  New approaches for interpreting projected bone densitometry data , 1992, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[32]  J. Kaufman,et al.  Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset. , 1992, The Journal of clinical endocrinology and metabolism.

[33]  W. Daughaday,et al.  Stimulation of supranormal growth in prepubertal, adult plateaued, and hypophysectomized female rats by large doses of rat growth hormone: physiological effects and adverse consequences. , 1987, Endocrinology.

[34]  W. Beamer,et al.  Inherited ateliotic dwarfism in mice. Characteristics of the mutation, little, on chromosome 6. , 1976, The Journal of heredity.