Delivering on the promise of bone morphogenetic proteins.
暂无分享,去创建一个
[1] C. Kirker-Head,et al. Potential applications and delivery strategies for bone morphogenetic proteins. , 2000, Advanced drug delivery reviews.
[2] T. Kohgo,et al. Effects of geometry of hydroxyapatite as a cell substratum in BMP-induced ectopic bone formation. , 2000, Journal of biomedical materials research.
[3] J O Hollinger,et al. Options for tissue engineering to address challenges of the aging skeleton. , 2000, Tissue engineering.
[4] S. Ludwig,et al. Osteoinductive bone graft substitutes , 2000, European Spine Journal.
[5] R. Sellers,et al. Repair of Articular Cartilage Defects One Year After Treatment with Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2)* , 2000, The Journal of bone and joint surgery. American volume.
[6] M. Urist,et al. Bone Morphogenetic Protein Excipients: Comparative Observations on Poloxamer , 2000, Plastic and reconstructive surgery.
[7] H. Uludaǧ,et al. Carrier systems for bone morphogenetic proteins. , 1999, Clinical orthopaedics and related research.
[8] A. Mikos,et al. Synthetic biodegradable polymers for orthopaedic applications. , 1999, Clinical orthopaedics and related research.
[9] K. Takaoka,et al. New synthetic absorbable polymers as BMP carriers: plastic properties of poly-D,L-lactic acid-polyethylene glycol block copolymers. , 1999, Journal of biomedical materials research.
[10] S. Boden. Bioactive factors for bone tissue engineering. , 1999, Clinical orthopaedics and related research.
[11] C. Hamanishi,et al. BONE DEFECT REPAIR USING SUBCUTANEOUSLY INDUCED BONE BY A BIORESORBABLE CALCIUM PHOSPHATE CEMENT COMBINED WITH rhBMP-2 , 1999 .
[12] I. Ishikawa,et al. Bone regeneration by recombinant human bone morphogenetic protein-2 in rat mandibular defects. An experimental model of defect filling. , 1999, Journal of periodontology.
[13] J. Hollinger,et al. Reconstruction of bone using calcium phosphate bone cements: a critical review. , 1999, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
[14] J. Wozney,et al. Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model. , 1999, Journal of biomedical materials research.
[15] Jeffrey Bonadio,et al. Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration , 1999, Nature Medicine.
[16] J. Poser,et al. Novel formulation of fibroblast growth factor‐2 in a hyaluronan gel accelerates fracture healing in nonhuman primates , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[17] S. Bulstra,et al. Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect. , 1999, The Journal of bone and joint surgery. British volume.
[18] A. Valentin‐Opran,et al. Clinical evaluation of rhBMP-2/ACS in orthopedic trauma: a progress report. , 1999, Orthopedics.
[19] S. Cook. Preclinical and clinical evaluation of osteogenic protein-1 (BMP-7) in bony sites. , 1999, Orthopedics.
[20] A Daluiski,et al. The effect of regional gene therapy with bone morphogenetic protein-2-producing bone-marrow cells on the repair of segmental femoral defects in rats. , 1999, The Journal of bone and joint surgery. American volume.
[21] S. Boden,et al. Posterolateral Lumbar Intertransverse Process Spine Arthrodesis With Recombinant Human Bone Morphogenetic Protein 2/Hydroxyapatite‐Tricalcium Phosphate After Laminectomy in the Nonhuman Primate , 1999, Spine.
[22] J O Hollinger,et al. Tissue-engineered bone biomimetic to regenerate calvarial critical-sized defects in athymic rats. , 1999, Journal of biomedical materials research.
[23] M. Marone,et al. Posterolateral intertransverse process spinal arthrodesis with rhBMP-2 in a nonhuman primate: important lessons learned regarding dose, carrier, and safety. , 1999, Journal of spinal disorders.
[24] B. Cunningham,et al. Osteogenic protein versus autologous interbody arthrodesis in the sheep thoracic spine. A comparative endoscopic study using the Bagby and Kuslich interbody fusion device. , 1999, Spine.
[25] K E Healy,et al. Ectopic bone formation via rhBMP-2 delivery from porous bioabsorbable polymer scaffolds. , 1998, Journal of biomedical materials research.
[26] William A. Pierce,et al. Effect of Recombinant Human Bone Morphogenetic Protein‐2 on Fracture Healing in a Goat Tibial Fracture Model , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[27] S. Cook,et al. Use of an osteoinductive biomaterial (rhOP-1) in healing large segmental bone defects. , 1998, Journal of orthopaedic trauma.
[28] Hiroshi Fukuda,et al. Recombinant Human Basic Fibroblast Growth Factor Accelerates Fracture Healing by Enhancing Callus Remodeling in Experimental Dog Tibial Fracture , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[29] Hollinger,et al. Sustained release emphasizing recombinant human bone morphogenetic protein-2. , 1998, Advanced drug delivery reviews.
[30] S. Boden,et al. Laparoscopic anterior spinal arthrodesis with rhBMP-2 in a titanium interbody threaded cage , 1998 .
[31] T. Gerhart,et al. Healing Bone Using Recombinant Human Bone Morphogenetic Protein 2 and Copolymer , 1998, Clinical orthopaedics and related research.
[32] P. Boyne,et al. Human recombinant BMP-2 in osseous reconstruction of simulated cleft palate defects. , 1998, The British journal of oral & maxillofacial surgery.
[33] J. Wozney,et al. Bone Formation with Use of rhBMP-2 (Recombinant Human Bone Morphogenetic Protein-2)* , 1997, The Journal of bone and joint surgery. American volume.
[34] J. Wozney,et al. Bone formation and osseointegration stimulated by rhBMP-2 following subantral augmentation procedures in nonhuman primates. , 1997, The International journal of oral & maxillofacial implants.
[35] E. Fu,et al. Bone morphogenetic protein-2 for peri-implant bone regeneration and osseointegration. , 1997, Clinical oral implants research.
[36] E. Morris,et al. The Effect of Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) on the Healing of Full-Thickness Defects of Articular Cartilage* , 1997, The Journal of bone and joint surgery. American volume.
[37] I. Asahina,et al. Repair of bone defect in primate mandible using a bone morphogenetic protein (BMP)-hydroxyapatite-collagen composite. , 1997, Journal of medical and dental sciences.
[38] T. Nakamura,et al. Ectopic bone induction in porous apatite-wollastonite-containing glass ceramic combined with bone morphogenetic protein. , 1997, Journal of biomedical materials research.
[39] J. Fiorellini,et al. A feasibility study evaluating rhBMP-2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation. , 1997, The International journal of periodontics & restorative dentistry.
[40] R. Marx,et al. A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation. , 1997, The International journal of periodontics & restorative dentistry.
[41] J. Wozney,et al. Periodontal repair in dogs: evaluation of rhBMP-2 carriers. , 1996, The International journal of periodontics & restorative dentistry.
[42] J. Wozney,et al. Maxillary alveolar cleft repair in dogs using recombinant human bone morphogenetic protein-2 and a polymer carrier. , 1996, Plastic and reconstructive surgery.
[43] J O Hollinger,et al. Role of bone substitutes. , 1996, Clinical orthopaedics and related research.
[44] S. Cook,et al. Osteogenic protein-1: biology and applications. , 1996, Clinical orthopaedics and related research.
[45] J. Michael Kabo,et al. Evaluation of rhBMP‐2 With an OPLA Carrier in a Canine Posterolateral (Transverse Process) Spinal Fusion Model , 1995, Spine.
[46] W. Hutton,et al. Experimental Spinal Fusion With Recombinant Human Bone Morphogenetic Protein‐2 , 1995, Spine.
[47] A. Weiland,et al. Immunolocalization and expression of bone morphogenetic proteins 2 and 4 in fracture healing , 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[48] S D Cook,et al. Effect of recombinant human osteogenic protein-1 on healing of segmental defects in non-human primates. , 1995, The Journal of bone and joint surgery. American volume.
[49] J. Wozney,et al. Periodontal repair in dogs: recombinant human bone morphogenetic protein-2 significantly enhances periodontal regeneration. , 1995, Journal of periodontology.
[50] G. Muschler,et al. Evaluation of Human Bone Morphogenetic Protein 2 in a Canine Spinal Fusion Model , 1994, Clinical orthopaedics and related research.
[51] J. Hollinger,et al. Osseous regeneration in the rat calvarium using novel delivery systems for recombinant human bone morphogenetic protein-2 (rhBMP-2). , 1994, Journal of biomedical materials research.
[52] W C Hayes,et al. Healing of large segmental defects in rat femurs is aided by RhBMP-2 in PLGA matrix. , 1994, Journal of biomedical materials research.
[53] S. Cook,et al. In Vivo Evaluation of Recombinant Human Osteogenic Protein (rhOP-1) Implants As a Bone Graft Substitute for Spinal Fusions , 1994, Spine.
[54] S. Cook,et al. The effect of recombinant human osteogenic protein-1 on healing of large segmental bone defects. , 1994, The Journal of bone and joint surgery. American volume.
[55] Brent Constantz,et al. Hydroxyapatite and Related Materials , 1994 .
[56] K. Takaoka,et al. Polylactic acid-polyethylene glycol block copolymer. A new biodegradable synthetic carrier for bone morphogenetic protein. , 1993, Clinical orthopaedics and related research.
[57] E. Wang,et al. Healing segmental femoral defects in sheep using recombinant human bone morphogenetic protein. , 1993, Clinical orthopaedics and related research.
[58] J. Wozney,et al. The bone morphogenetic protein family and osteogenesis , 1992, Molecular reproduction and development.
[59] V. Rosen,et al. The healing of segmental bone defects, induced by recombinant human bone morphogenetic protein (rhBMP-2). A radiographic, histological, and biomechanical study in rats. , 1992, The Journal of bone and joint surgery. American volume.
[60] E. Wang,et al. Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation. , 1991, Archives of otolaryngology--head & neck surgery.
[61] J. Heckman,et al. The use of bone morphogenetic protein in the treatment of non-union in a canine model. , 1991, The Journal of bone and joint surgery. American volume.
[62] V. Rosen,et al. Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[63] E. Drier,et al. OP‐1 cDNA encodes an osteogenic protein in the TGF‐beta family. , 1990, The EMBO journal.
[64] V. Rosen,et al. Recombinant human bone morphogenetic protein induces bone formation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[65] V. Goldberg,et al. Ectopic induction of cartilage and bone by water-soluble proteins from bovine bone using a polyanhydride delivery vehicle. , 1989, Journal of biomedical materials research.
[66] V. Rosen,et al. Novel regulators of bone formation: molecular clones and activities. , 1988, Science.
[67] V. Rosen,et al. Purification and characterization of other distinct bone-inducing factors. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[68] K Ono,et al. Ectopic bone induction on and in porous hydroxyapatite combined with collagen and bone morphogenetic protein. , 1988, Clinical orthopaedics and related research.
[69] T. Schmalzried,et al. Bone repair induced by bone morphogenetic protein in ulnar defects in dogs. , 1986, The Journal of bone and joint surgery. British volume.
[70] A. Reddi,et al. Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[71] Michael Jarcho,et al. Calcium phosphate ceramics as hard tissue prosthetics. , 1981, Clinical orthopaedics and related research.
[72] M. Urist,et al. Bone: Formation by Autoinduction , 1965, Science.
[73] E. Burger,et al. Bone morphogenetic proteins in human bone regeneration. , 2000, European journal of endocrinology.
[74] K. Groot. Carriers that concentrate native bone morphogenetic protein in vivo. , 1998 .
[75] D. Kohn,et al. Development and characterization of a biodegradable polyphosphate. , 1997, Journal of biomedical materials research.
[76] J H Brekke,et al. A rationale for delivery of osteoinductive proteins. , 1996, Tissue engineering.
[77] M. Urist,et al. Composites of bone morphogenetic protein (BMP) and type IV collagen, coral-derived coral hydroxyapatite, and tricalcium phosphate ceramics , 1996, International Orthopaedics.
[78] K. Leong,et al. Poly(α-hydroxy acids). Carriers for bone morphogenetic proteins , 1996 .