Effect of stimulation of the cerebellum on noradrenaline and adrenaline secretion of the adrenal gland in the cat.

In 14 cats anesthetized with sodium pentobarbital the adrenal venous blood was collected through a cannula inserted into the adrenal vein, and the vermis of the cerebellum was electrically stimulated. The adrenal venous blood samples were analyzed fluorimetrically for adrenaline and noradrenaline. In 2 cats electrical stimulation of the central lobule produced a definite increase in adrenal medullary secretion. Catecholamines liberated on stimulation were predominantly noradrenaline. A similar result was obtained in one cat in which the uvula of the posterior lobe was stimulated. In these 3 cats a marked elevation of blood pressure was observed during stimulation. Slight increase in adrenal medullary secretion was produced in 4 cats by stimulation of the medullary portion of the cerebellum.