Inherited causes of clonal haematopoiesis in 97,691 whole genomes
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Ivana V. Yang | Sebastian M. Armasu | Andrew D. Johnson | Benjamin D. Heavner | May E. Montasser | Nicholette D. Palmer | Erin J. Buth | James M. Casella | Sarah C. Nelson | Christopher R. Gignoux | Caitlin P. McHugh | Min A. Jhun | Ellen M. Schmidt | Pamela H. Russell | M. Fornage | K. Lunetta | L. Hou | J. Manson | C. Carty | A. Reiner | S. Redline | S. Gabriel | G. Abecasis | E. Lander | J. Kitzman | Hongyu Zhao | E. Boerwinkle | S. Tishkoff | D. Nickerson | M. Zody | R. Casaburi | B. Make | E. Silverman | Xihong Lin | L. Mestroni | D. Weeks | D. Chasman | E. Burchard | W. Sheu | K. Ardlie | D. V. Berg | E. Benjamin | P. Ellinor | R. Vasan | P. Scheet | C. Kooperberg | L. Almasy | R. Duggirala | J. Blangero | F. Aguet | I. Ruczinski | B. Ebert | S. Kardia | B. Psaty | E. Lange | S. Nekhai | D. Roden | M. Taub | D. Arking | Michael H. Preuss | C. Willer | S. Kathiresan | K. Taylor | J. Rotter | L. Becker | S. Vrieze | T. Thornton | B. Cade | J. Brody | N. Sotoodehnia | K. Barnes | D. Becker | L. Bielak | P. Peyser | A. Stilp | T. Sofer | A. Szpiro | G. Papanicolaou | C. Laurie | B. Custer | R. Gerszten | Karen L. Bunting | L. Cupples | Xiuqing Guo | J. Broome | M. Cho | C. Hersh | A. Ratan | K. North | B. Snively | F. Sciurba | N. Gupta | P. Natarajan | D. Saleheen | James G. Wilson | C. Lange | J. Bis | S. Wenzel | P. Castaldi | L. Fulton | S. Rich | J. Barnard | Jennifer A. Smith | Wei Zhao | M. de Andrade | L. Launer | S. Kardia | S. Heckbert | D. Arnett | S. Choi | Y. Sung | N. Franceschini | S. Musani | K. Schwander | L. Yanek | U. Broeckel | A. Correa | Q. Duan | J. O'connell | N. Palmer | B. Freedman | T. Kelly | P. McArdle | A. Parsa | B. Mitchell | S. Dutcher | R. Loos | S. Erzurum | B. Levy | D. Meyers | M. Montasser | Y. Hung | E. Kenny | R. Mathias | J. Curran | Weiniu Gan | J. Nasser | J. Engreitz | P. Auer | J. Hixson | A. Bick | C. Fulco | Erik L. Bao | J. Peralta | M. Flickinger | J. Heit | R. Kaplan | S. Lubitz | J. Haessler | L. Lange | Honghuang Lin | Kevin Sandow | J. Wessel | Mao Fu | A. Beitelshees | T. Pollin | R. Chung | S. Germer | C. Gignoux | T. Blackwell | T. Fingerlin | Keng-Han Lin | D. Qiao | A. Manichaikul | B. Hobbs | A. Niroula | L. Williams | K. Ryan | Jiang He | S. Aslibekyan | Rakhi Naik | V. Sheehan | Namiko Abe | M. Irvin | I. Yang | D. Darbar | J. Mychaleckyj | H. Ochs-Balcom | L. Rasmussen-Torvik | C. Jaquish | Daniel N Harris | D. Jain | S. Nelson | S. Gogarten | C. Laurie | N. Rafaels | S. Zekavat | M. Chaffin | A. Mak | J. Lasky-Su | A. Moscati | M. Daya | Bertha A Hidalgo | B. Konkle | J. Johnsen | C. Montgomery | D. Taliun | R. Wallace | L. Raffield | P. Vandehaar | H. Mei | L. Phillips | S. Ament | L. Margolin | N. Smith | Q. Wong | Jonathan Seidman | V. Carey | C. Sztalryd | E. Streeten | Wen-Jane Lee | D. Vaidya | Heming Wang | C. Roselli | E. Whitsel | J. Cardwell | L. Ekunwe | Huichun Xu | Craig W. Johnson | V. Sankaran | C. Frazar | L. Weng | M. Boorgula | R. Deka | M. Wheeler | S. McGarvey | A. Walts | B. Heavner | J. Floyd | N. Zaghloul | Steven Salzberg | S. Zoellner | Catherine Tong | S. Jaiswal | J. Su | P. Kachroo | C. Gu | Aniket Shetty | Yi-Cheng Chang | E. Sabino | Joseph Wu | C. Clish | R. Minster | Bo-Juen Chen | Satish K. Nandakumar | C. Damcott | S. Armasu | Margery L S Gass | Jee-Young Moon | S. Graw | Rongze Yang | P. Durda | J. Weinstock | Mollie A Minear | M. McDonald | T. Assimes | S. Salimi | S. Fullerton | Hemant Tiwari | K. Hoth | A. E. Lin | T. Beaty | Rebecca L. Beer | L. Emery | Julie Mikulla | P. Qasba | I. Chen | C. Gibson | M. LeBoff | Jennifer A. Brody | R. G. Barr | Jody M Sylvia | C. Hwu | H. Gui | D. Applebaum-Bowden | Sean K. McFarland | M. Snyder | Wonji Kim | Jiwon Lee | E. Cornell | M. Szeto | Xiaotian Liao | B. Burugula | Fei Fei Wang | Erin J Buth | Pinkal M. Desai | Alyna T Khan | Peter Anderson | Pramod Anugu | Allison Ashley-Koch | E. Barron-Casella | Lucas Barwick | Marcos Bezerra | Christy Chang | J. Curtis | S. David | Yan Gao | Auyon J. Ghosh | Harald H. H Goring | Y. Guan | Michael N. Hall | N. Hawley | Elliott Hong | R. Johnston | Michael Kessler | Greg Kinney | David Levine | Yu Liu | James Luo | S. Mathai | Susanne May | N. Min | Stanford E. Mwasongwe | T. Naseri | Bonnie Neltner | T. O’Connor | James Perry | Julia Powers Becker | S. Ruuska | Christopher Scheller | Josh Smith | Tanja Smith | S. Smoller | Garrett Storm | Simeon I. Taylor | Tarik Walker | Kayleen Williams | Snow Xueyan Zhao | Xiang Zhou | S. Weiss | D. Zhi | David E. Glahn | Terri L Beaty | Yu Liu | Shanshan Gao | Marsha M. Wheeler | Seunggeun Lee | Zhaohui Qin | D. Levy | R. Tracy | R. Gibbs | D. Tirschwell | M. Moll | Yun Li | Lisa Martin | K. Watson | A. Smith | Xiaohui Li | S. Chavan | Brian H. Silver | M. B. Shoemaker | D. Paik | Aakrosh Ratan | A. Johnson | J. Lewis | U. Peters | D. Rao | Kenneth M. Rice | Marco V. Perez | C. Seidman | D. Avramopoulos | Gerald Beck | Carlos Bustamante | Wei-Min Chen | Carolyn Crandall | Bruce Gelb | M. Geraci | M. Gladwin | Kimberly Jones | Shannon Kelly | Henry Lin | M. Telen | Bruce Weir | Lee-Ming Chuang | Yingze Zhang | Suzy Comhair | Robert M Reed | Cathy C. Laurie | Colleen P. Davis | Lesley E. Tinker | Ryan Hernandez | Daniel J. McGoldrick | Michael Y. Tsai | Sayantan Das | Yongmei Liu | Simin Liu | J. Crapo | Michael DeBaun | Daniel Grine | Amol Shetty | M. Taylor | Hua Tang | Álvaro Alonso | Scott Devine | Charles Farber | Daoping Gong | J. Hokanson | H. Kramer | Michael P. Mahaney | J. Pankow | E. Regan | M. Threlkeld | Girish N. Nadkarni | Russell Bowler | Xiaofeng Zhu | D. Demeo | Christine Albert | M. Chung | Charles B. Eaton | H. Huston | Rebecca D. Jackson | Holly B. Kramer | J. Lefaive | Wendy S. Post | Amol C. Shetty | K. Chang | Adel El Boueiz | Muagututi’a Sefuiva Reupena | Chao (Agnes) Hsiung | D. A. Schwartz | David M. Herrington | Carla Wilson | Matthew J. Leventhal | H. M. Kang | T. Naseri | Cecelia Laurie | Don Bowden | Lawrence F. Bielak | Namiko Christine Laura Alvaro Seth Peter Pramod Deborah D Abe Albert Almasy Alonso Ament Anderson An | P. Benos | Larry Bielak | Xiaoqi (Priscilla) Geng | Stephanie L. Sherman | L. Barwick | A. Ashley-Koch | Pinkal Desai | G. Nadkarni | C. Johnson | A. Smith | Russell P Bowler | G. Kinney | Wei Zhao | Dhananjay Vaidya | Henry J. Lin | F. Wang | Ellen M. Schmidt | B. Psaty | S. Kardia | Wendy S Post | Degui Zhi | R. Loos | Honghuang Lin | Merry-Lynn N. McDonald | Michael R. DeBaun | Honghuang Lin | K. Taylor | Peter Vandehaar | Wei Zhao | A. Correa | J. Seidman | Daniel Taliun | Lawrence S. Phillips | H. Goring | Stephanie M. Fullerton | Stella Aslibekyan | Deborah Applebaum-Bowden | S. Lee | Yu Liu | Jennifer A. Smith | Hemant K. Tiwari | S. Comhair | K. Taylor | Yongmei Liu | Adel Boueiz | Jeffery R O'connell | Lisa W. Martin | Hemant K. Tiwari | Cathy C. Laurie | Michael D. Kessler | B. Gelb | Adam A. Szpiro | P. Anugu
[1] Brian E. Cade,et al. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program , 2019, Nature.
[2] Javier Gracia Tabuenca,et al. Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells , 2020, Nature.
[3] Jesse M. Engreitz,et al. Genome-wide maps of enhancer regulation connect risk variants to disease genes , 2020, bioRxiv.
[4] S. Gabriel,et al. Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis , 2019, Circulation.
[5] Neva C. Durand,et al. Activity-by-Contact model of enhancer-promoter regulation from thousands of CRISPR perturbations , 2019, Nature Genetics.
[6] Anshul Kundaje,et al. The ENCODE Blacklist: Identification of Problematic Regions of the Genome , 2019, Scientific Reports.
[7] Jerry Fowler,et al. System for Quality‐Assured Data Analysis: Flexible, reproducible scientific workflows , 2019, Genetic epidemiology.
[8] Ryan L. Collins,et al. Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes , 2019, bioRxiv.
[9] Samuel F. Bakhoum,et al. Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations , 2018, Nature.
[10] K. Ballman,et al. Somatic mutations precede acute myeloid leukemia years before diagnosis , 2018, Nature Medicine.
[11] Juan P. Bustamante,et al. Next generation sequencing panel based on single molecule molecular inversion probes for detecting genetic variants in children with hypopituitarism , 2018, Molecular genetics & genomic medicine.
[12] Hongyu Zhao,et al. A statistical framework for cross-tissue transcriptome-wide association analysis , 2018, bioRxiv.
[13] Yeting Zhang,et al. Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects , 2018, Nature Communications.
[14] R. Levine,et al. Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies. , 2018, Cell stem cell.
[15] N. Callander,et al. Hyaluronan and proteoglycan link protein 1 (HAPLN1) activates bortezomib-resistant NF-κB activity and increases drug resistance in multiple myeloma , 2017, The Journal of Biological Chemistry.
[16] May E. Montasser,et al. Deep-coverage whole genome sequences and blood lipids among 16,324 individuals , 2017, Nature Communications.
[17] Lars G Fritsche,et al. Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies , 2017, Nature Genetics.
[18] E. Cuppen,et al. MutationalPatterns: comprehensive genome-wide analysis of mutational processes , 2017, bioRxiv.
[19] Nicola J. Rinaldi,et al. Enhancing GTEx by bridging the gaps between genotype, gene expression, and disease , 2017, Nature Genetics.
[20] Kari Stefansson,et al. Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly. , 2017, Blood.
[21] S. Gabriel,et al. Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease , 2017, The New England journal of medicine.
[22] A. LaCasce,et al. Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[23] Nicholas Eriksson,et al. Germ line variants predispose to both JAK2 V617F clonal hematopoiesis and myeloproliferative neoplasms. , 2016, Blood.
[24] T. Druley,et al. Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults , 2016, Nature Communications.
[25] David C. Jones,et al. Landscape of somatic mutations in 560 breast cancer whole genome sequences , 2016, Nature.
[26] Jian Gu,et al. Mosaic loss of chromosome Y is associated with common variation near TCL1A , 2016, Nature Genetics.
[27] M. Stratton,et al. Clock-like mutational processes in human somatic cells , 2015, Nature Genetics.
[28] D. Bates,et al. Linear Mixed-Effects Models using 'Eigen' and S4 , 2015 .
[29] Matti Pirinen,et al. FINEMAP: efficient variable selection using summary data from genome-wide association studies , 2015, bioRxiv.
[30] B. Ebert,et al. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. , 2015, Blood.
[31] G. Abecasis,et al. An efficient and scalable analysis framework for variant extraction and refinement from population-scale DNA sequence data , 2015, Genome research.
[32] S. Horvath,et al. HIV-1 Infection Accelerates Age According to the Epigenetic Clock , 2015, The Journal of infectious diseases.
[33] M. McCarthy,et al. Age-related clonal hematopoiesis associated with adverse outcomes. , 2014, The New England journal of medicine.
[34] E. Schadt,et al. Geroscience: Linking Aging to Chronic Disease , 2014, Cell.
[35] S. Gabriel,et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. , 2014, The New England journal of medicine.
[36] D. Bates,et al. Fitting Linear Mixed-Effects Models Using lme4 , 2014, 1406.5823.
[37] S. Monti,et al. The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation. , 2013, Blood.
[38] Jay Shendure,et al. Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation , 2013, Genome research.
[39] Wei Lu,et al. Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer , 2013, Nature Genetics.
[40] A. Sivachenko,et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples , 2013, Nature Biotechnology.
[41] Paul Scheet,et al. Haplotype-based profiling of subtle allelic imbalance with SNP arrays , 2013, Genome research.
[42] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[43] Devin C. Koestler,et al. DNA methylation arrays as surrogate measures of cell mixture distribution , 2012, BMC Bioinformatics.
[44] Richard T. Barfield,et al. CpGassoc: an R function for analysis of DNA methylation microarray data , 2012, Bioinform..
[45] Chris Williams,et al. RNA-SeQC: RNA-seq metrics for quality control and process optimization , 2012, Bioinform..
[46] O. Abdel-Wahab,et al. Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. , 2011, Cancer cell.
[47] G. Abecasis,et al. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes , 2010, Genetic epidemiology.
[48] S. Bandinelli,et al. Red cell distribution width and mortality in older adults: a meta-analysis. , 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.
[49] Andrew Collins,et al. JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms , 2009, Nature Genetics.
[50] Kenneth Offit,et al. A germline JAK2 SNP is associated with predisposition to the development of JAK2V617F-positive myeloproliferative neoplasms , 2009, Nature Genetics.
[51] Ashot Harutyunyan,et al. A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms , 2009, Nature Genetics.
[52] F. Schmidt. Meta-Analysis , 2008 .
[53] Cheng Li,et al. Adjusting batch effects in microarray expression data using empirical Bayes methods. , 2007, Biostatistics.
[54] R. Houlston,et al. Variants in the ATM-BRCA2-CHEK2 axis predispose to chronic lymphocytic leukemia. , 2006, Blood.
[55] J. Lubiński,et al. CHEK2 is a multiorgan cancer susceptibility gene. , 2004, American journal of human genetics.