An estrogen antagonist, cyclofenil, has anti-dengue-virus activity

[1]  Tatsuya Takagi,et al.  Dengue Virus and Its Inhibitors: A Brief Review. , 2018, Chemical & pharmaceutical bulletin.

[2]  J. Low,et al.  Current Status of Dengue Therapeutics Research and Development , 2017, The Journal of infectious diseases.

[3]  E. Damonte,et al.  Antiviral activity of natural and synthetic β-carbolines against dengue virus. , 2016, Antiviral research.

[4]  Jianhong Zhou,et al.  Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ERα) and Biochemical Characterization of the ERα-Hsp70 Interaction , 2016, PloS one.

[5]  Philip F. Hughes,et al.  An inducible heat shock protein 70 small molecule inhibitor demonstrates anti-dengue virus activity, validating Hsp70 as a host antiviral target. , 2016, Antiviral research.

[6]  S. Tajima,et al.  Two different dengue virus strains in the Japanese epidemics of 2014 , 2016, Virus Genes.

[7]  R. Andino,et al.  Defining Hsp70 Subnetworks in Dengue Virus Replication Reveals Key Vulnerability in Flavivirus Infection , 2015, Cell.

[8]  C. Sousa,et al.  Impact of a Dengue Outbreak Experience in the Preventive Perceptions of the Community from a Temperate Region: Madeira Island, Portugal , 2015, PLoS neglected tropical diseases.

[9]  V. Vaillant,et al.  Autochthonous case of dengue in France, October 2013. , 2013, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[10]  David Beer,et al.  Ten years of dengue drug discovery: progress and prospects. , 2013, Antiviral research.

[11]  John S. Brownstein,et al.  The global distribution and burden of dengue , 2013, Nature.

[12]  H. Goto,et al.  Discovery of Novel Antiviral Agents Directed Against the Influenza A Virus Nucleoprotein , 2012 .

[13]  M. Fernandez-Garcia,et al.  Pathogenesis of flavivirus infections: using and abusing the host cell. , 2009, Cell host & microbe.

[14]  Philippe Després,et al.  Human genetic determinants of dengue virus susceptibility. , 2009, Microbes and infection.

[15]  Charles M. Rice,et al.  Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis , 2008, Nature Reviews Microbiology.

[16]  S. Tajima,et al.  Characterization of Asn130-to-Ala mutant of dengue type 1 virus NS1 protein , 2008, Virus Genes.

[17]  Hussein H. Aly,et al.  Anti-hepatitis C Virus Activity of Tamoxifen Reveals the Functional Association of Estrogen Receptor with Viral RNA Polymerase NS5B* , 2007, Journal of Biological Chemistry.

[18]  M. Blettner,et al.  Vascular leakage in severe dengue virus infections: a potential role for the nonstructural viral protein NS1 and complement. , 2006, The Journal of infectious diseases.

[19]  S. Tajima,et al.  Nineteen nucleotides in the variable region of 3' non-translated region are dispensable for the replication of dengue type 1 virus in vitro. , 2006, Virus research.

[20]  S. Tajima,et al.  Development and Evaluation of Fluorogenic TaqMan Reverse Transcriptase PCR Assays for Detection of Dengue Virus Types 1 to 4 , 2004, Journal of Clinical Microbiology.

[21]  A. Nisalak,et al.  High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever. , 2002, The Journal of infectious diseases.

[22]  Y. S. Lin,et al.  Immunopathogenesis of dengue virus infection. , 2001, Journal of biomedical science.

[23]  Duane J. Gubler,et al.  Dengue and Dengue Hemorrhagic Fever , 1998, Clinical Microbiology Reviews.

[24]  R. Mason,et al.  Retrograde trafficking of both Golgi complex and TGN markers to the ER induced by nordihydroguaiaretic acid and cyclofenil diphenol. , 1998, Journal of cell science.

[25]  W. Pratt,et al.  Steroid receptor interactions with heat shock protein and immunophilin chaperones. , 1997, Endocrine reviews.

[26]  C. Rice,et al.  Genetic analysis of the yellow fever virus NS1 protein: identification of a temperature-sensitive mutation which blocks RNA accumulation , 1997, Journal of virology.

[27]  L. Reed,et al.  A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS , 1938 .

[28]  Y. Murakami,et al.  Selective estrogen receptor modulators inhibit hepatitis C virus infection at multiple steps of the virus life cycle. , 2013, Microbes and infection.

[29]  Bachti Alisjahbana,et al.  Epidemiology of dengue and dengue hemorrhagic fever in a cohort of adults living in Bandung, West Java, Indonesia. , 2005, The American journal of tropical medicine and hygiene.

[30]  C. Rice,et al.  Flavivirus genome organization, expression, and replication. , 1990, Annual review of microbiology.

[31]  L. J. Reed.  A simple method of estimating fifty per cent end-points. , 1938 .