Cryotherapy for skin cancer: results over a 5‐year period using liquid nitrogen spray cryosurgery

Three hundred and ninety five selected non‐melanoma skin cancers were treated and followed up during the period 1981–1986, using a standardized cryosurgical technique. There was an overall cure rate of 97%. Recurrences were seen in 6 out of 225 (2.7%) treated basal cell carcinomas at a median time of 18 months, I of 34 (2.9%) squamous cell carcinomas, with a recurrence at 6 months post‐operatively and I out of 128 (0.8%) of Bowen's tumours which recurred 6 months after treatment. The patients were treated as out‐patients using local anaesthesia and all tolerated the treatment well.

[1]  Cahan Wg CRYOSURGERY OF MALIGNANT AND BENIGN TUMORS. , 1965 .

[2]  J. Elwood,et al.  Links between Exposure to Ultraviolet Radiation and Skin Cancer , 1987, Journal of the Royal College of Physicians of London.

[3]  S. A. Zacarian Cryosurgery of skin cancer, and cryogenic techniques in dermatology , 1969 .

[4]  R. Bennett,et al.  Failure of curettage and electrodesiccation for removal of basal cell carcinoma. , 1984, Archives of dermatology.

[5]  R. Dawber,et al.  The historical and scientific basis of cryosurgery , 1982, Clinical and experimental dermatology.

[6]  R. Davie,et al.  The significance of incomplete excision in patients with basal cell carcinoma. , 1987, British journal of plastic surgery.

[7]  S. Albright Treatment of skin cancer using multiple modalities. , 1982, Journal of the American Academy of Dermatology.

[8]  D. Torre Cryosurgical treatment of epitheliomas using the cone-spray technique. , 1977, The Journal of dermatologic surgery and oncology.

[9]  J. Shepherd,et al.  Effect of freezing the helix and the rim or edge of the human and pig ear. , 1984, The Journal of dermatologic surgery and oncology.

[10]  A. Gage Cryo Corner: What Temperature Is Lethal for Cells? , 1979 .

[11]  H. H. Whitehouse LIQUID AIR IN DERMATOLOGY; ITS INDICATIONS AND LIMITATIONS. , 1907 .

[12]  E. G. Kuflik Cryosurgery for Skin Cancer and Cutaneous Disorders , 1985 .

[13]  J. Crissey,et al.  Curettage and electrodesiccation as a method of treatment for epitheliomas of the skin , 1971, Journal of surgical oncology.

[14]  A. Gage What temperature is lethal for cells? , 1979, The Journal of dermatologic surgery and oncology.

[15]  F. Nahai,et al.  The meaning of surgical margins. , 1984, Plastic and reconstructive surgery.

[16]  J. Zitelli,et al.  Surgical margins for basal cell carcinoma. , 1987, Archives of dermatology.

[17]  T. Hindson,et al.  Clobetasol propionate ointment reduces inflammation after cryotherapy , 1985, The British journal of dermatology.

[18]  P. Mazur Cryobiology: the freezing of biological systems. , 1970, Science.