Expression of the proprotein convertases PC1 and PC2 mRNAs in thyrotropin releasing hormone neurons of the rat paraventricular nucleus of hypothalamus

[1]  N. Seidah,et al.  cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[2]  W. Ma,et al.  Differential coexpression of genes encoding prothyrotropin-releasing hormone (pro-TRH) and prohormone convertases (PC1 and PC2) in rat brain neurons: implications for differential processing of pro-TRH. , 1996, Endocrinology.

[3]  I. Lindberg,et al.  Role of PC2 in Proenkephalin Processing: Antisense and Overexpression Studies , 1996, Journal of neurochemistry.

[4]  R. Mains,et al.  Proneuropeptide Y processing in large dense-core vesicles: manipulation of prohormone convertase expression in sympathetic neurons using adenoviruses , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[5]  Y. Loh,et al.  Pro‐Thyrotropin‐Releasing Hormone Processing by Recombinant PC1 , 1995, Journal of neurochemistry.

[6]  Y. Loh,et al.  Processing of prothyrotropin-releasing hormone (Pro-TRH) by bovine intermediate lobe secretory vesicle membrane PC1 and PC2 enzymes. , 1995, Endocrinology.

[7]  M. Smith,et al.  Stress increases brain-derived neurotropic factor messenger ribonucleic acid in the hypothalamus and pituitary. , 1995, Endocrinology.

[8]  G. Martens,et al.  7B2 is a neuroendocrine chaperone that transiently interacts with prohormone convertase PC2 in the secretory pathway , 1994, Cell.

[9]  R. Axel,et al.  The function and differential sorting of a family of aplysia prohormone processing enzymes , 1994, Neuron.

[10]  N. Seidah,et al.  The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions. , 1994, Biochimie.

[11]  R. Mains,et al.  Rapid Increases in Peptide Processing Enzyme Expression in Hippocampal Neurons , 1993, Journal of neurochemistry.

[12]  M. Wessendorf,et al.  A cryptic peptide from the preprothyrotropin-releasing hormone precursor stimulates thyrotropin gene expression. , 1993, Endocrinology.

[13]  J. Charli,et al.  Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus. , 1993, Neuroendocrinology.

[14]  M. Chrétien,et al.  Gene expression of prohormone and proprotein convertases in the rat CNS: a comparative in situ hybridization analysis , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[15]  R. Zoeller,et al.  Ethanol blocks the cold-induced increase in thyrotropin-releasing hormone mRNA in paraventricular nuclei but not the cold-induced increase in thyrotropin. , 1992, Brain research. Molecular brain research.

[16]  N. Seidah,et al.  Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary. , 1992, Molecular endocrinology.

[17]  Computer Methods in Nuclei Cartography , 1992 .

[18]  J. Dixon,et al.  Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats. , 1991, Endocrinology.

[19]  R. Mains,et al.  Prohormone-converting enzymes: regulation and evaluation of function using antisense RNA. , 1991, Molecular endocrinology.

[20]  G. Ponce,et al.  Some events of thyrotropin-releasing hormone metabolism are regulated in lactating and cycling rats. , 1991, Neuroendocrinology.

[21]  J. Thorner,et al.  Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro- beta-NGF in vivo , 1990, The Journal of cell biology.

[22]  H. Vaudry,et al.  Processing of thyrotropin-releasing hormone (TRH) prohormone in the rat olfactory bulb generates novel TRH-related peptides. , 1990, Endocrinology.

[23]  M Chrétien,et al.  cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases. , 1990, DNA and cell biology.

[24]  R. Lechan,et al.  Thyrotropin-releasing-hormone-immunoreactive innervation of thyrotropin-releasing-hormone-tuberoinfundibular neurons in rat hypothalamus: anatomical basis to suggest ultrashort feedback regulation. , 1990, Neuroendocrinology.

[25]  H. Vaudry,et al.  Processing of thyrotropin-releasing hormone prohormone (pro-TRH) generates a biologically active peptide, prepro-TRH-(160-169), which regulates TRH-induced thyrotropin secretion. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[26]  S. M. Cockle TRH‐extended peptides in the olfactory lobe are formed by incomplete cleavage at pairs of arginine residues in the TRH prohormone , 1990, FEBS letters.

[27]  R. Goodman,et al.  Thyrotropin-releasing hormone (TRH) precursor processing. Characterization of mature TRH and non-TRH peptides synthesized by transfected mammalian cells. , 1989, The Journal of biological chemistry.

[28]  T. Hökfelt,et al.  Distribution and coexistence of corticotropin-releasing factor-, neurotensin-, enkephalin-, cholecystokinin-, galanin- and vasoactive intestinal polypeptide/peptide histidine isoleucine-like peptides in the parvocellular part of the paraventricular nucleus. , 1989, Neuroendocrinology.

[29]  J. Thorner,et al.  Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Gabriel Corkidi Blanco Système d'analyse de préparations histologiques par imagerie numérique : Histo 200 : application à l'étude physiopathologique de la maladie de Parkinson , 1989 .

[31]  H. Vaudry,et al.  Processing of thyrotropin-releasing hormone prohormone (pro-TRH) generates pro-TRH-connecting peptides. Identification and characterization of prepro-TRH-(160-169) and prepro-TRH-(178-199) in the rat nervous system. , 1988, The Journal of biological chemistry.

[32]  T. Nakamura,et al.  Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases. , 1988, Biochemical and biophysical research communications.

[33]  I. Jackson,et al.  Post-translational processing of thyrotropin-releasing hormone precursor in rat brain: identification of 3 novel peptides derived from pro TRH , 1988, Brain Research.

[34]  H. Davidson,et al.  Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases , 1988, Nature.

[35]  L. Orci,et al.  A view of acidic intracellular compartments , 1988, The Journal of cell biology.

[36]  J. Charli,et al.  Neuronal TRH synthesis: developmental and circadian TRH mRNA levels. , 1988, Biochemical and biophysical research communications.

[37]  J. Kauer,et al.  Thyroid hormone regulates TRH biosynthesis in the paraventricular nucleus of the rat hypothalamus. , 1987, Science.

[38]  R. Zoeller,et al.  Thyroid hormones regulate levels of thyrotropin-releasing-hormone mRNA in the paraventricular nucleus. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[39]  R. Lechan,et al.  Identification and characterization of thyrotropin-releasing hormone precursor peptides in rat brain. , 1987, Endocrinology.

[40]  H. Hoefler,et al.  Localization of thyrotropin-releasing hormone prohormone messenger ribonucleic acid in rat brain in situ hybridization. , 1987, Endocrinology.

[41]  D. Smyth,et al.  Specific processing of the thyrotropin-releasing prohormone in rat brain and spinal cord. , 1987, European journal of biochemistry.

[42]  W. Young Corticotropin-releasing factor mRNA in the hypothalamus is affected differently by drinking saline and by dehydration. , 1986, FEBS letters.

[43]  R. Goodman,et al.  Thyrotropin-releasing hormone precursor: characterization in rat brain. , 1986, Science.