Determination of Picoxystrobin Residues in Watermelon Field Trials by Rapid Resolution Liquid Chromatography Triple Quadrupole Mass Spectrometry: Dissipation Kinetics and Terminal Residues

A simple, rapid and efficient method for the determination of picoxystrobin in watermelon ecosystem was established and validated via QuEChERS (quick, easy cheap, effective, rugged and safe) method using rapid resolution liquid chromatography tandem mass spectrometry (RRLC-MS/MS). The average recoveries (n=5) of picoxystrobin in three matrix at three fortification levels ranged from 89.4% to 102.6%. The limits of detection (LODs) were lower than 1.28×10 _4 mg L 1. The limits of quantification (LOQs) were 0.001 mg kg _1 for watermelon flesh (whole watermelon) and 0.005 mg kg _1 for soil. The half-life of picoxystrobin of whole watermelon (soil) in Shandong and Anhui were 1.43 (4.18) days and 3.71 (17.32) days, respectively. The picoxystrobin terminal residues in watermelon were lower than 0.001 mg kg _1 under the recommended dosages, which were far below the maximum residue limit (MRL) set by China (0.05 mg kg 1). These obtained data not only provide scientific information about safety estimation of picoxystrobin in watermelon and the kinetics of dissipation, but also facilitate trade exportation of watermelon for China.

[1]  Ashkan Nabavi-Pelesaraei,et al.  Neural network modeling of energy use and greenhouse gas emissions of watermelon production systems , 2016 .

[2]  J. Himmelstein,et al.  Fusarium wilt of watermelon: Towards sustainable management of a re-emerging plant disease , 2015 .

[3]  Fengmao Liu,et al.  Air-assisted liquid-liquid microextraction by solidifying the floating organic droplets for the rapid determination of seven fungicide residues in juice samples. , 2015, Analytica chimica acta.

[4]  Xiaochu Chen,et al.  Rapid and sensitive analysis of nine fungicide residues in chrysanthemum by matrix extraction-vortex-assisted dispersive liquid-liquid microextraction. , 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[5]  R. Kierzek,et al.  Determination of pesticide residues in samples of green minor crops by gas chromatography and ultra performance liquid chromatography coupled to tandem quadrupole mass spectrometry. , 2015, Talanta.

[6]  Haiyang Li,et al.  Determination and dissipation of flucarbazone-sodium and its metabolite in wheat and soils by LC-MS/MS , 2014 .

[7]  Xingang Liu,et al.  Simultaneous determination of fipronil and its major metabolites in corn and soil by ultra-performance liquid chromatography-tandem mass spectrometry , 2014 .

[8]  X. Wu,et al.  Determination of strobilurin fungicide residues in fruits and vegetables by micellar electrokinetic capillary chromatography with sweeping. , 2014, Journal of chromatographic science.

[9]  Xue Liu,et al.  Graphene as dispersive solidphase extraction materials for pesticides LC-MS/MS multi-residue analysis in leek, onion and garlic , 2014, Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment.

[10]  Fengmao Liu,et al.  Dissipation and residues of clethodim and its oxidation metabolites in a rape-field ecosystem using QuEChERS and liquid chromatography/tandem mass spectrometry. , 2014, Food chemistry.

[11]  K. Semple,et al.  Isolation and characterisation of azoxystrobin degrading bacteria from soil. , 2014, Chemosphere.

[12]  F. Wang,et al.  Ultrasound-assisted surfactant-enhanced emulsification microextraction with solidification of floating organic droplet followed by high performance liquid chromatography for the determination of strobilurin fungicides in fruit juice samples. , 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[13]  R. Dornellas,et al.  Determination of the fungicide picoxystrobin using anodic stripping voltammetry on a metal film modified glassy carbon electrode , 2013 .

[14]  Hongyan Zhang,et al.  Amine modified graphene as reversed-dispersive solid phase extraction materials combined with liquid chromatography-tandem mass spectrometry for pesticide multi-residue analysis in oil crops. , 2013, Journal of chromatography. A.

[15]  C. Pan,et al.  Pesticide Multi-Residue Analysis in Tea Using d-SPE Sample Cleanup with Graphene Mixed with Primary Secondary Amine and Graphitized Carbon Black Prior to LC–MS/MS , 2013, Chromatographia.

[16]  L. Lagunas-Allué,et al.  Comparison of four extraction methods for the determination of fungicide residues in grapes through gas chromatography-mass spectrometry. , 2012, Journal of chromatography. A.

[17]  A. Melo,et al.  Monitoring pesticide residues in greenhouse tomato by combining acetonitrile-based extraction with dispersive liquid-liquid microextraction followed by gas-chromatography-mass spectrometry. , 2012, Food chemistry.

[18]  A. Abad‐Somovilla,et al.  Development of monoclonal antibody-based competitive immunoassays for the detection of picoxystrobin in cereal and oilseed flours , 2012 .

[19]  C. Pan,et al.  Dispersive cleanup of acetonitrile extracts of tea samples by mixed multiwalled carbon nanotubes, primary secondary amine, and graphitized carbon black sorbents. , 2012, Journal of agricultural and food chemistry.

[20]  S. Cunha,et al.  Multipesticide residue analysis in maize combining acetonitrile-based extraction with dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry. , 2011, Journal of chromatography. A.

[21]  Philip W. Lee,et al.  Rapid determination of melamine in soil and strawberry by liquid chromatography–tandem mass spectrometry , 2011 .

[22]  Bo Chen,et al.  Analysis of pesticide residues using the Quick Easy Cheap Effective Rugged and Safe (QuEChERS) pesticide multiresidue method in traditional Chinese medicine by gas chromatography with electron capture detection. , 2011, Chemosphere.

[23]  Martha B. Adaime,et al.  Development of a fast multiresidue method for the determination of pesticides in dry samples (wheat grains, flour and bran) using QuEChERS based method and GC-MS , 2011 .

[24]  Marek Biziuk,et al.  Determination of pesticide residues in food matrices using the QuEChERS methodology , 2011 .

[25]  M. Á. González-Curbelo,et al.  Insecticides extraction from banana leaves using a modified QuEChERS method , 2011 .

[26]  A. Fernández-Alba,et al.  Evaluation of various QuEChERS based methods for the analysis of herbicides and other commonly used pesticides in polished rice by LC-MS/MS. , 2011, Talanta.

[27]  A. Abad‐Somovilla,et al.  Hapten synthesis, monoclonal antibody generation, and development of competitive immunoassays for the analysis of picoxystrobin in beer. , 2010, Analytica chimica acta.

[28]  M. Hernández-Córdoba,et al.  Stir bar sorptive extraction coupled to liquid chromatography for the analysis of strobilurin fungicides in fruit samples. , 2010, Journal of chromatography. A.

[29]  J. Hajšlová,et al.  Identification/quantification of multiple pesticide residues in food plants by ultra-high-performance liquid chromatography-time-of-flight mass spectrometry. , 2010, Journal of chromatography. A.

[30]  S. Walorczyk,et al.  Development and validation of a multi-residue method for the determination of pesticides in honeybees using acetonitrile-based extraction and gas chromatography-tandem quadrupole mass spectrometry. , 2009, Journal of chromatography. A.

[31]  M. Hernández-Córdoba,et al.  Method development and validation for strobilurin fungicides in baby foods by solid-phase microextraction gas chromatography-mass spectrometry. , 2009, Journal of chromatography. A.

[32]  André de Kok,et al.  Comprehensive multi-residue method for the target analysis of pesticides in crops using liquid chromatography-tandem mass spectrometry. , 2007, Journal of chromatography. A.

[33]  A. Balinova,et al.  Solid-phase extraction on sorbents of different retention mechanisms followed by determination by gas chromatography-mass spectrometric and gas chromatography-electron capture detection of pesticide residues in crops. , 2007, Journal of chromatography. A.

[34]  E. Mermaid.  Evaluation of Two Fast and Easy Methods for Pesticide Residue Analysis in Fatty Food Matrixes , 2005 .

[35]  T. Wehner,et al.  The Genes of Watermelon , 2004 .

[36]  A. Keinath,et al.  Evaluation of fungicides for prevention and management of powdery mildew on watermelon , 2004 .

[37]  Mick Hamer,et al.  The strobilurin fungicides. , 2002, Pest management science.

[38]  T. Anke,et al.  Strobilurins: Evolution of a New Class of Active Substances. , 1999, Angewandte Chemie.

[39]  D. MacDougall,et al.  Guidelines for data acquisition and data quality evaluation in environmental chemistry , 1980 .