The anti-galloping method was proposed for the 6×1520 mm2 large cross section conductor. The galloping model was established by using nonlinear finite element method and considering geometric nonlinear, aerodynamic nonlinear and initial deformation. The galloping characteristics and the critical conditions to excite galloping were obtained for the large cross section conductor. And the anti-galloping effect was also evaluated by using the rotary clamp spacers. The results show that the multi-bundled conductors are more vulnerable to the galloping phenomenon than the single conductors under the same ice and wind conditions. And the galloping characteristics obtained by 1520 mm2 large cross section conductor are basically the same with other cross section conductors. The anti-galloping effect can meet the requirement by using rotary clamp spacer for the 6×1520 mm2 large cross section conductor in the easy galloping areas. And even in the harshest ice and wind conditions, the galloping amplitude can be reduced in the largest extent and the time to excite galloping can be greatly extended.