Polarization Filter for Biomedical Tissue Optical Imaging

Abstract— A technique based on the degree that light is depolarized when propagating inside tissues is demonstrated for optical imaging in biomedical systems. The difference in the degree of polarization of the emerging light allows for the discrimination of different types of tissues. The technique was investigated in the transillumination and back‐scattering geometry and in both cases the potential of this method to image and separate out different types of tissues is demonstrated.

[1]  R R Alfano,et al.  Time-Resolved Imaging of Translucent Droplets in Highly Scattering Turbid Media , 1994, Science.

[2]  I. Freund,et al.  Angular intensity and polarization dependence of diffuse transmission through random media , 1993 .

[3]  H Chen,et al.  Two-dimensional imaging through diffusing media using 150-fs gated electronic holography techniques. , 1991, Optics letters.

[4]  S. Svanberg,et al.  Time-resolved transillumination for medical diagnostics. , 1990, Optics letters.

[5]  J. Schmitt,et al.  Use of polarized light to discriminate short-path photons in a multiply scattering medium. , 1992, Applied optics.

[6]  R. Alfano,et al.  Ballistic 2-D Imaging Through Scattering Walls Using an Ultrafast Optical Kerr Gate , 1991, Science.

[7]  R R Alfano,et al.  Temporal gating in highly scattering media by the degree of optical polarization. , 1996, Optics letters.

[8]  Jack Feinberg,et al.  Time-resolved holography , 1991, Nature.

[9]  Christian Brosseau,et al.  Depolarization behavior of multiple scattered light from an optically dense random medium , 1997, Other Conferences.

[10]  M D Duncan,et al.  Time-gated imaging through scattering media using stimulated Raman amplification. , 1991, Optics letters.

[11]  J. Fujimoto,et al.  Optical Coherence Tomography , 1991 .

[12]  Robert R. Alfano,et al.  Time resolved depolarization of multiple backscattered light from random media , 1989 .

[13]  R. Alfano,et al.  Optical polarization imaging. , 1997, Applied optics.

[14]  J C Hebden,et al.  Evaluating the spatial resolution performance of a time-resolved optical imaging system. , 1992, Medical physics.

[15]  K Wada,et al.  Extraction of quasi-straightforward-propagating photons from diffused light transmitting through a scattering medium by polarization modulation. , 1995, Optics letters.

[16]  M D Duncan,et al.  Resolution limits for imaging through turbid media with diffuse light. , 1993, Optics letters.