Autophagy ux modulates Tax viral protein distribution pattern in human T-cell lymphotropic virus type 1 (HTLV-1) infection

Nicolás Ducasa Instituto de investigaciones biomédicas en retrovirus y SIDA (INBIRS) https://orcid.org/0000-00034455-8295 Daniel Grasso Instituto de Estudios de la Inmunidad Humoral (IDEHU) Paula Benencio Instituto de investigaciones biomédicas en retrovirus y SIDA (INBIRS) Daniela Papademetrio Instituto de Estudios de la Inmunidad Humoral (IDEHU) Mirna Biglione Instituto de investigaciones en retrovirus y SIDA (INBIRS) Fatah Kashanchi Laboratory of Molecular Virology Maria Noe Garcia Instituto de Estudios de la Inmunidad Humoral (IDEHU) Carolina Berini (  caroberini@gmail.com ) CONICETUniversidad de Buenos Aires

[1]  M. Matsuoka,et al.  40 years of the human T-cell leukemia virus: past, present, and future , 2019, F1000Research.

[2]  W. Jackson,et al.  So Many Roads: the Multifaceted Regulation of Autophagy Induction , 2018, Molecular and Cellular Biology.

[3]  R. Woodman,et al.  Human T-Lymphotropic Virus type 1c subtype proviral loads, chronic lung disease and survival in a prospective cohort of Indigenous Australians , 2018, PLoS neglected tropical diseases.

[4]  M. Romanelli,et al.  HTLV Deregulation of the NF-κB Pathway: An Update on Tax and Antisense Proteins Role , 2018, Front. Microbiol..

[5]  R. Mahieux,et al.  HTLV-1, the Other Pathogenic Yet Neglected Human Retrovirus: From Transmission to Therapeutic Treatment , 2017, Viruses.

[6]  Elsje G. Otten,et al.  mTORC1 as the main gateway to autophagy , 2017, Essays in biochemistry.

[7]  Yang Zhang,et al.  The autophagy molecule Beclin 1 maintains persistent activity of NF-κB and Stat3 in HTLV-1-transformed T lymphocytes. , 2015, Biochemical and biophysical research communications.

[8]  D. Klionsky,et al.  An overview of autophagy: morphology, mechanism, and regulation. , 2014, Antioxidants & redox signaling.

[9]  Hong-Gang Wang,et al.  HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains , 2013, Oncogene.

[10]  M. Romanelli,et al.  Highlights on distinctive structural and functional properties of HTLV Tax proteins , 2013, Front. Microbiol..

[11]  Z. Klase,et al.  The Cellular Autophagy Pathway Modulates Human T-Cell Leukemia Virus Type 1 Replication , 2012, Journal of Virology.

[12]  A. Gessain,et al.  Epidemiological Aspects and World Distribution of HTLV-1 Infection , 2012, Front. Microbio..

[13]  S. Kudchodkar,et al.  Viruses and autophagy , 2009, Reviews in medical virology.

[14]  Hua Cheng,et al.  HTLV-1 Tax Is a Critical Lipid Raft Modulator That Hijacks IκB Kinases to the Microdomains for Persistent Activation of NF-κB* , 2009, Journal of Biological Chemistry.

[15]  G. Barber,et al.  STING an Endoplasmic Reticulum Adaptor that Facilitates Innate Immune Signaling , 2008, Nature.

[16]  F. Kashanchi,et al.  Transcriptional and post-transcriptional gene regulation of HTLV-1 , 2005, Oncogene.

[17]  R. Gaynor,et al.  Protein domains involved in both in vivo and in vitro interactions between human T-cell leukemia virus type I tax and CREB , 1995, Journal of virology.

[18]  W. Dunn.  Studies on the mechanisms of autophagy: maturation of the autophagic vacuole , 1990, The Journal of cell biology.