Speckle detection in ultrasonic images using unsupervised clustering techniques

In ultrasonic images, identification of speckled regions helps to estimate probe movement as well as improve performance of algorithms for adaptive speckle suppression and the elevational separation of B-scans by speckle decorrelation. By tracking FDS patch displacements over time we can calculate strain and detect tumor location. Previous studies for speckle detection were based on classification techniques which estimated parameters of the statistical distribution which were based on observation data and ultrasound echo envelope signal. However, in this study, we proposed a new combination of statistical features which were extracted from the ultrasound images and explored their properties for the speckle detection. These features were used as inputs to the unsupervised clustering algorithms for the speckle classification. We used five different types of unsupervised techniques and compared their performance by feeding different combinations of the statistical features. In order to quantitatively compare statistical features and classification methods, as ground truth, we used simulations of cyst and fetus ultrasound images which were generated using Field II ultrasound simulation program[1]. Initial results showed that by combining two statistical models (K and Rayleigh distributions) we can get best speck detection signatures to feed unsupervised classifiers and maximize speckle detection performance.

[1]  P M Shankar,et al.  A model for ultrasonic scattering from tissues based on the K distribution. , 1995, Physics in medicine and biology.

[2]  Jørgen Jensen,et al.  Simulation of advanced ultrasound systems using Field II , 2004, 2004 2nd IEEE International Symposium on Biomedical Imaging: Nano to Macro (IEEE Cat No. 04EX821).

[3]  Andrew H. Gee,et al.  Decompression and speckle detection for ultrasound images using the homodyned k-distribution , 2003, Pattern Recognit. Lett..

[4]  L O Hall,et al.  Review of MR image segmentation techniques using pattern recognition. , 1993, Medical physics.

[5]  Denis Friboulet,et al.  Segmentation of Myocardial Regions in Echocardiography Using the Statistics of the Radio-Frequency Signal , 2007, FIMH.

[6]  Andrea Tagarelli,et al.  Clustering Uncertain Data Via K-Medoids , 2008, SUM.

[7]  B. Goldberg,et al.  Comparisons of the Rayleigh and K-distribution models using in vivo breast and liver tissue. , 1998, Ultrasound in medicine & biology.

[8]  J. Greenleaf,et al.  Ultrasound echo envelope analysis using a homodyned K distribution signal model. , 1994, Ultrasonic imaging.

[9]  J. Greenleaf,et al.  Ultrasound Echo Envelope Analysis Using a Homodyned K Distribution Signal Model , 1994 .

[10]  L. R. Dice Measures of the Amount of Ecologic Association Between Species , 1945 .

[11]  Sue-Fen Huang,et al.  Unsupervised clustering algorithm based on normalized Mahalanobis distances , 2010 .

[12]  Masahiro Hiraoka,et al.  Ferromagnetic hyperthermia in rabbit eyes using a new glass-ceramic thermoseed , 1994, Graefe's Archive for Clinical and Experimental Ophthalmology.

[13]  Jerry L Prince,et al.  Current methods in medical image segmentation. , 2000, Annual review of biomedical engineering.

[14]  Léandre Pourcelot,et al.  Effective Density Estimators Based on the K Distribution: Interest of Low and Fractional Order Moments , 1998, Ultrasonic imaging.

[15]  Yoshifumi Amemiya,et al.  Magnetic induction hyperthermia for brain tumor using ferromagnetic implant with low Curie temperature , 2004, Journal of Neuro-Oncology.

[16]  G. Fichtinger,et al.  P3E-9 Ultrasound Speckle Detection Using Low Order Moments , 2006, 2006 IEEE Ultrasonics Symposium.

[17]  P. Shankar,et al.  Characterization of ultrasonic B-scans using non-Rayleigh statistics. , 1995, Ultrasound in medicine & biology.

[18]  Ferenc Szeifert,et al.  Modified Gath-Geva fuzzy clustering for identification of Takagi-Sugeno fuzzy models , 2002, IEEE Trans. Syst. Man Cybern. Part B.

[19]  J C Bamber,et al.  Ultrasonic B-scanning: a computer simulation , 1980, Physics in medicine and biology.

[20]  John W. Sammon,et al.  A Nonlinear Mapping for Data Structure Analysis , 1969, IEEE Transactions on Computers.

[21]  William R. Brody,et al.  Segmentation algorithms for detecting microcalcifications in mammograms , 1997, IEEE Transactions on Information Technology in Biomedicine.