A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia

[1]  M. Daly,et al.  The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders , 2017, Molecular Psychiatry.

[2]  Eun Hye Yoon,et al.  Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1. , 2017, Biochemical and biophysical research communications.

[3]  Minoru Kanehisa,et al.  KEGG: new perspectives on genomes, pathways, diseases and drugs , 2016, Nucleic Acids Res..

[4]  N. Müller What role does inflammation play in schizophrenia? , 2016, Expert review of neurotherapeutics.

[5]  L. Wain,et al.  Haplotype estimation for biobank scale datasets , 2016, Nature Genetics.

[6]  Benjamin A. Logsdon,et al.  Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia , 2016, Nature Neuroscience.

[7]  J. Auwerx,et al.  Mitonuclear communication in homeostasis and stress , 2016, Nature Reviews Molecular Cell Biology.

[8]  G. Lynch,et al.  Evidence of Mitochondrial Dysfunction within the Complex Genetic Etiology of Schizophrenia , 2015, Molecular Neuropsychiatry.

[9]  Karl R. Clauser,et al.  MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins , 2015, Nucleic Acids Res..

[10]  Gary D. Bader,et al.  Cytoscape.js: a graph theory library for visualisation and analysis , 2015, Bioinform..

[11]  Celso Arango,et al.  Inflammation in schizophrenia: A question of balance , 2015, Neuroscience & Biobehavioral Reviews.

[12]  J. Enríquez,et al.  The complex crosstalk between mitochondria and the nucleus: What goes in between? , 2015, The international journal of biochemistry & cell biology.

[13]  Joris M. Mooij,et al.  MAGMA: Generalized Gene-Set Analysis of GWAS Data , 2015, PLoS Comput. Biol..

[14]  S. Marie,et al.  Decreased AKT1/mTOR pathway mRNA expression in short-term bipolar disorder , 2015, European Neuropsychopharmacology.

[15]  M. Berk,et al.  Mitochondrial dysfunction in schizophrenia: Pathways, mechanisms and implications , 2015, Neuroscience & Biobehavioral Reviews.

[16]  J. Kane The role of NMDA receptors in schizophrenia. , 2015, The Journal of clinical psychiatry.

[17]  Laura J. Scott,et al.  Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways , 2015, Nature Neuroscience.

[18]  Aiqing He,et al.  Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder , 2014, Molecular Psychiatry.

[19]  Caleb Webber,et al.  GeneNet Toolbox for MATLAB: a flexible platform for the analysis of gene connectivity in biological networks , 2014, Bioinform..

[20]  Vladimir I. Vladimirov,et al.  A meta-analysis of gene expression quantitative trait loci in brain , 2014, Translational Psychiatry.

[21]  C. Spencer,et al.  Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.

[22]  M C O'Donovan,et al.  Copy number variation in schizophrenia in Sweden , 2014, Molecular Psychiatry.

[23]  S. Kapur,et al.  Alterations in cortical and extrastriatal subcortical dopamine function in schizophrenia: systematic review and meta-analysis of imaging studies , 2013, British Journal of Psychiatry.

[24]  J. Mill,et al.  Analysis of HSPA8 and HSPA9 mRNA expression and promoter methylation in the brain and blood of Alzheimer's disease patients. , 2013, Journal of Alzheimer's disease : JAD.

[25]  Jonathan P. Beauchamp,et al.  GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment , 2013, Science.

[26]  M. Berk,et al.  Immuno-inflammatory, oxidative and nitrosative stress, and neuroprogressive pathways in the etiology, course and treatment of schizophrenia , 2013, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[27]  Cole M. Haynes,et al.  Signaling the mitochondrial unfolded protein response. , 2013, Biochimica et biophysica acta.

[28]  M. Tarnopolsky,et al.  Metabolite measurements in the caudate nucleus, anterior cingulate cortex and hippocampus among patients with mitochondrial disorders: a case-control study using proton magnetic resonance spectroscopy. , 2013, CMAJ open.

[29]  Kazuo Yamada,et al.  Brain region-specific altered expression and association of mitochondria-related genes in autism , 2012, Molecular Autism.

[30]  J. Marchini,et al.  Fast and accurate genotype imputation in genome-wide association studies through pre-phasing , 2012, Nature Genetics.

[31]  J. Moreira,et al.  Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity. , 2012, Journal of psychiatric research.

[32]  Michael R Knowles,et al.  Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis , 2012, Nature Genetics.

[33]  T. Woo,et al.  Oxidative stress in schizophrenia: An integrated approach , 2011, Neuroscience & Biobehavioral Reviews.

[34]  Josyf Mychaleckyj,et al.  Robust relationship inference in genome-wide association studies , 2010, Bioinform..

[35]  Gary D. Bader,et al.  The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function , 2010, Nucleic Acids Res..

[36]  Giovanni Scardoni,et al.  Analyzing biological network parameters with CentiScaPe , 2009, Bioinform..

[37]  J. Chory,et al.  Coordination of gene expression between organellar and nuclear genomes , 2008, Nature Reviews Genetics.

[38]  F. Dudbridge,et al.  Estimation of significance thresholds for genomewide association scans , 2008, Genetic epidemiology.

[39]  Radu V. Craiu,et al.  Stratified false discovery control for large‐scale hypothesis testing with application to genome‐wide association studies , 2006, Genetic epidemiology.

[40]  P. Verstreken,et al.  Mitochondria at the Synapse , 2006, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

[41]  B. Singer,et al.  Controlling the False Discovery Rate: A New Application to Account for Multiple and Dependent Tests in Local Statistics of Spatial Association , 2006 .

[42]  K. N. Chandrika,et al.  Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets , 2006, Nature Genetics.

[43]  M. Guha,et al.  Mitochondria-to-nucleus stress signaling in mammalian cells: nature of nuclear gene targets, transcription regulation, and induced resistance to apoptosis. , 2005, Gene.

[44]  Sue Povey,et al.  Gene map of the extended human MHC , 2004, Nature Reviews Genetics.

[45]  I. Nimmo-Smith,et al.  Hypofrontality in schizophrenia: a meta‐analysis of functional imaging studies , 2004, Acta psychiatrica Scandinavica.

[46]  P. Sullivan,et al.  Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. , 2003, Archives of general psychiatry.

[47]  John D. Storey,et al.  Statistical significance for genomewide studies , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[48]  H. Murck Magnesium and Affective Disorders , 2002, Nutritional neuroscience.

[49]  J. Rapoport,et al.  Cerebral glucose metabolism in childhood onset schizophrenia , 1997, Psychiatry Research: Neuroimaging.

[50]  D. Weinberger,et al.  Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia. , 1992, Archives of general psychiatry.

[51]  J D Brodie,et al.  Persistence of cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography. , 1985, The American journal of psychiatry.

[52]  F. Kooy HYPERGLYÆMIA IN MENTAL DISORDERS , 1919 .

[53]  S. Brunak,et al.  A scored human protein–protein interaction network to catalyze genomic interpretation , 2017, Nature Methods.

[54]  O. Fattal,et al.  Review of the literature on major mental disorders in adult patients with mitochondrial diseases. , 2006, Psychosomatics.

[55]  R. Yolken,et al.  Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress , 2004, Molecular Psychiatry.

[56]  J. Blass Glucose/mitochondria in neurological conditions. , 2002, International review of neurobiology.

[57]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .