Functional imaging: CT and MRI.

[1]  Yung-Chang Chen,et al.  Multi-threshold dimension vector for texture analysis and its application to liver tissue classification , 1993, Pattern Recognit..

[2]  A. Clough,et al.  Transit time dispersion in the pulmonary arterial tree. , 1998, Journal of applied physiology.

[3]  R. Buxton Principles of Tracer Kinetics , 2002 .

[4]  H. Suhonen,et al.  Differences in the time course of proximal and distal airway response to inhaled histamine studied by synchrotron radiation CT. , 2006, Journal of applied physiology.

[5]  J L Lehr,et al.  Nonuniformity of canine lung washout by high-frequency ventilation. , 1986, Journal of applied physiology.

[6]  W Vaalburg,et al.  Nitrogen-13 and xenon-133 ventilation studies. , 1984, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[7]  H. Kauczor,et al.  3He‐MRI‐based measurements of intrapulmonary p O2 and its time course during apnea in healthy volunteers: first results, reproducibility, and technical limitations , 2000, NMR in biomedicine.

[8]  Ye Xu,et al.  MDCT-based 3-D texture classification of emphysema and early smoking related lung pathologies , 2006, IEEE Transactions on Medical Imaging.

[9]  E. Hoffman,et al.  Static versus prospective gated non-breath hold volumetric MDCT imaging of the lungs. , 2005, Academic radiology.

[10]  J. Venegas,et al.  Effects of respiratory variables on regional gas transport during high-frequency ventilation. , 1988, Journal of applied physiology.

[11]  S. Lai-Fook,et al.  Arterial, capillary, and venous transit times and dispersion measured in isolated rabbit lungs. , 1995, Journal of applied physiology.

[12]  John P Mugler,et al.  Evaluation of asthma with hyperpolarized helium-3 MRI: correlation with clinical severity and spirometry. , 2006, Chest.

[13]  M. Oudkerk,et al.  Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism: a prospective study , 2002, The Lancet.

[14]  E. Hoffman,et al.  CT-based assessment of regional pulmonary microvascular blood flow parameters. , 2003, Journal of applied physiology.

[15]  P. Suortti,et al.  Effect of tidal volume on distribution of ventilation assessed by synchrotron radiation CT in rabbit. , 2004, Journal of applied physiology.

[16]  T. Iwasawa,et al.  Prediction of postoperative pulmonary function using perfusion magnetic resonance imaging of the lung , 2002, Journal of magnetic resonance imaging : JMRI.

[17]  Michael L Goris,et al.  An automated approach to quantitative air trapping measurements in mild cystic fibrosis. , 2003, Chest.

[18]  René M. Botnar,et al.  Inherently self‐calibrating non‐cartesian parallel imaging , 2005, Magnetic resonance in medicine.

[19]  D. Levin,et al.  Pulmonary blood flow heterogeneity during hypoxia and high-altitude pulmonary edema. , 2005, American journal of respiratory and critical care medicine.

[20]  B. M. Goodson,et al.  Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials, and organisms. , 2002, Journal of magnetic resonance.

[21]  H. Kauczor,et al.  Assessment of a single‐acquisition imaging sequence for oxygen‐sensitive 3He‐MRI , 2002, Magnetic resonance in medicine.

[22]  E. V. van Beek,et al.  Comparison between 2D and 3D gradient‐echo sequences for MRI of human lung ventilation with hyperpolarized 3He , 2004, Magnetic resonance in medicine.

[23]  H C Charles,et al.  Cystic fibrosis: combined hyperpolarized 3He-enhanced and conventional proton MR imaging in the lung--preliminary observations. , 1999, Radiology.

[24]  A Zeiher,et al.  Digital angiographic impulse response analysis of regional myocardial perfusion. Estimation of coronary flow, flow reserve, and distribution volume by compartmental transit time measurement in a canine model. , 1991, Circulation research.

[25]  Susan M. Astley,et al.  Classification of breast tissue by texture analysis , 1992, Image Vis. Comput..

[26]  R. Bowtell,et al.  MR tagging of human lungs using hyperpolarized 3He gas , 2003, Journal of magnetic resonance imaging : JMRI.

[27]  H. Kauczor,et al.  Chronic thromboembolic pulmonary hypertension — assessment by magnetic resonance imaging , 2006, European Radiology.

[28]  M. Reiser,et al.  [Dual-source CT in chest pain diagnosis]. , 2007, Der Radiologe.

[29]  Tinsu Pan,et al.  Dynamic ventilation imaging from four-dimensional computed tomography , 2006, Physics in medicine and biology.

[30]  I. Ruset,et al.  Optical pumping system design for large production of hyperpolarized. , 2006, Physical review letters.

[31]  S. Suzuki,et al.  Correlation of quantitative CT with selective alveolobronchogram and pulmonary function tests in emphysema. , 1994, Chest.

[32]  John P Mugler,et al.  The variability of regional airflow obstruction within the lungs of patients with asthma: assessment with hyperpolarized helium-3 magnetic resonance imaging. , 2007, The Journal of allergy and clinical immunology.

[33]  M. O'Doherty,et al.  Use of imaging in the management of malignant pleural mesothelioma. , 2005, Clinical radiology.

[34]  James M Balter,et al.  Mutual information based CT registration of the lung at exhale and inhale breathing states using thin-plate splines. , 2004, Medical physics.

[35]  H. Kauczor,et al.  Preoperative assessment and follow-up of congenital abnormalities of the pulmonary arteries using CT and MRI , 2006, European Radiology.

[36]  W. Manning,et al.  Simultaneous acquisition of spatial harmonics (SMASH): Fast imaging with radiofrequency coil arrays , 1997, Magnetic resonance in medicine.

[37]  James R. Brookeman,et al.  Lung Air Spaces: MR Imaging Evaluation with , 1999 .

[38]  E. Hoffman Medical Imaging 1997: Physiology and Function from Multidimensional Images , 1995 .

[39]  Edwin J R van Beek,et al.  MRI of helium‐3 gas in healthy lungs: Posture related variations of alveolar size , 2004, Journal of magnetic resonance imaging : JMRI.

[40]  M. Reiser,et al.  Material differentiation by dual energy CT: initial experience , 2007, European Radiology.

[41]  B. Zaret,et al.  Nuclear cardiology : state of the art and future directions , 1993 .

[42]  Edwin J R van Beek,et al.  Combined helium‐3/proton magnetic resonance imaging measurement of ventilated lung volumes in smokers compared to never‐smokers , 2005, Journal of magnetic resonance imaging : JMRI.

[43]  J. Fredberg,et al.  Alveolar pressure nonhomogeneity during small-amplitude high-frequency oscillation. , 1984, Journal of applied physiology: respiratory, environmental and exercise physiology.

[44]  Eric A. Hoffman,et al.  CT-based assessment of regional pulmonary blood flow parameters: an update , 1999, Medical Imaging.

[45]  V. Boldea,et al.  Simulation of four-dimensional CT images from deformable registration between inhale and exhale breath-hold CT scans. , 2006, Medical physics.

[46]  Thomas Guerrero,et al.  Quantification of regional ventilation from treatment planning CT. , 2005, International journal of radiation oncology, biology, physics.

[47]  E A Zerhouni,et al.  In vivo measurements of airway reactivity using high-resolution computed tomography. , 1991, The American review of respiratory disease.

[48]  Eric A Hoffman,et al.  Effect of low-xenon and krypton supplementation on signal/noise of regional CT-based ventilation measurements. , 2007, Journal of applied physiology.

[49]  T A Wilson,et al.  Nonuniform expansion of constricted dog lungs. , 1996, Journal of applied physiology.

[50]  G. Raff,et al.  Use of multidetector computed tomography for the assessment of acute chest pain: a consensus statement of the North American Society of Cardiac Imaging and the European Society of Cardiac Radiology , 2007, European Radiology.

[51]  Ralf Tetzlaff,et al.  Proton magnetic resonance imaging for assessment of lung function and respiratory dynamics. , 2007, European journal of radiology.

[52]  D Gur,et al.  Dynamic computed tomography of the lung: regional ventilation measurements. , 1979, Journal of computer assisted tomography.

[53]  Renuka Uppaluri,et al.  Fractal analysis of high-resolution CT images as a tool for quantification of lung diseases , 1995, Medical Imaging.

[54]  S. Rich,et al.  Analysis of regional pulmonary enhancement in dogs by ultrafast computed tomography. , 1992, Investigative radiology.

[55]  W. Webb High-resolution computed tomography of the lung: normal and abnormal anatomy. , 1991, Seminars in roentgenology.

[56]  Martine Remy-Jardin,et al.  Management of suspected acute pulmonary embolism in the era of CT angiography: a statement from the Fleischner Society. , 2007, Radiology.

[57]  J Hildebrandt,et al.  Determination of regional ventilation and perfusion in the lung using xenon and computed tomography. , 2001, Journal of applied physiology.

[58]  H Adams,et al.  An appraisal of CT pulmonary density mapping in normal subjects. , 1991, Clinical radiology.

[59]  B. Stoel,et al.  Repeatability of Lung Density Measurements with Low-Dose Computed Tomography in Subjects with &agr;-1-Antitrypsin Deficiency–Associated Emphysema , 2001, Investigative radiology.

[60]  S. M. Collins,et al.  Ultrasound characterization of acute myocardial ischemia by quantitative texture analysis. , 1986, Ultrasonic imaging.

[61]  Edwin J R van Beek,et al.  Quantitative analysis of regional airways obstruction using dynamic hyperpolarized 3He MRI—Preliminary results in children with cystic fibrosis , 2005, Journal of magnetic resonance imaging : JMRI.

[62]  D M Murphy,et al.  Local pulmonary ventilation using nonradioactive xenon-enhanced ultrafast computed tomography. , 1989, Chest.

[63]  M Salerno,et al.  Dynamic spiral MRI of pulmonary gas flow using hyperpolarized 3He: Preliminary studies in healthy and diseased lungs , 2001, Magnetic resonance in medicine.

[64]  Tilo Winkler,et al.  Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans. , 2002, Journal of applied physiology.

[65]  P. Chevalier,et al.  Topographical distribution of regional lung volume in anesthetized dogs. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

[66]  Xenon Enhanced CT Imaging of Local Pulmonary Ventilation. , 1996 .

[67]  William Stanford,et al.  Feasibility of quantitative texture analysis of cardiac magnetic resonance imagery: preliminary results , 1994, Medical Imaging.

[68]  J R Brookeman,et al.  Lung air spaces: MR imaging evaluation with hyperpolarized 3He gas. , 1999, Radiology.

[69]  E A Zerhouni,et al.  Spontaneous airways constrict during breath holding studied by high-resolution computed tomography. , 1994, Chest.

[70]  C. Sanders Imaging of Emphysema , 1992 .

[71]  H. Yonas,et al.  Xenon CT cerebral blood flow: past, present, and future. , 1995, AJNR. American journal of neuroradiology.

[72]  Edwin J R van Beek,et al.  Rapid Lung Volumetry Using Ultrafast Dynamic Magnetic Resonance Imaging During Forced Vital Capacity Maneuver: Correlation With Spirometry , 2007, Investigative radiology.

[73]  Jim M. Wild,et al.  Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry , 2006, European Radiology.

[74]  R. Munden,et al.  CT, MR, and PET imaging in staging of non-small-cell lung cancer. , 2005, Seminars in roentgenology.

[75]  Eduard E de Lange,et al.  Hyperpolarized HHe 3 MRI of the lung in cystic fibrosis: assessment at baseline and after bronchodilator and airway clearance treatment. , 2005, Academic radiology.

[76]  J. Best,et al.  CT measurements of lung density in life can quantitate distal airspace enlargement--an essential defining feature of human emphysema. , 1988, The American review of respiratory disease.

[77]  G. Guillot,et al.  CPMG measurements and ultrafast imaging in human lungs with hyperpolarized helium‐3 at low field (0.1 T) , 2002, Magnetic resonance in medicine.

[78]  Wei Lu,et al.  Tracking lung tissue motion and expansion/compression with inverse consistent image registration and spirometry. , 2007, Medical physics.

[79]  N H Holstein-Rathlou,et al.  Volume adjustment of lung density by computed tomography scans in patients with emphysema , 2004, Acta radiologica.

[80]  D. Lynch,et al.  Quantitative computed tomography detects air trapping due to asthma. , 1994, Chest.

[81]  Randall C. Wetzel,et al.  High‐Resolution Computed Tomography—Physiologic Correlation , 1993, Journal of thoracic imaging.

[82]  E A Zerhouni,et al.  Individual airway constrictor response heterogeneity to histamine assessed by high-resolution computed tomography. , 1993, Journal of applied physiology.

[83]  R W Glenny,et al.  High-resolution maps of regional ventilation utilizing inhaled fluorescent microspheres. , 1997, Journal of applied physiology.

[84]  K. Murase,et al.  Primary pulmonary hypertension: 3D dynamic perfusion MRI for quantitative analysis of regional pulmonary perfusion. , 2007, AJR. American journal of roentgenology.

[85]  K. Stierstorfer,et al.  First performance evaluation of a dual-source CT (DSCT) system , 2006, European Radiology.

[86]  Y. Ohno,et al.  MR angiography with sensitivity encoding (SENSE) for suspected pulmonary embolism: comparison with MDCT and ventilation-perfusion scintigraphy. , 2004, AJR. American journal of roentgenology.

[87]  K Torizuka,et al.  Stratified Impairment of Pulmonary Ventilation in “Diffuse Panbronchiolitis: “ PET and CT Studies , 1989, Journal of computer assisted tomography.

[88]  S Katsuragawa,et al.  Image feature analysis and computer-aided diagnosis in digital radiography: classification of normal and abnormal lungs with interstitial disease in chest images. , 1989, Medical physics.

[89]  H. Kauczor,et al.  3He-MRI in follow-up of lung transplant recipients , 2004, European Radiology.

[90]  T. Takishima,et al.  Three-dimensional quantitative coronary angiography , 1990, IEEE Transactions on Biomedical Engineering.

[91]  S. Lele,et al.  Parameter estimation and confidence intervals for Xe-CT ventilation studies: a Monte Carlo approach. , 1998, Journal of applied physiology.

[92]  Eric A Hoffman,et al.  Regional pulmonary blood flow in dogs by 4D-X-ray CT. , 2006, Journal of applied physiology.

[93]  L. Schad,et al.  MR tissue characterization of intracranial tumors by means of texture analysis. , 1993, Magnetic resonance imaging.

[94]  W. Happer,et al.  Biological magnetic resonance imaging using laser-polarized 129Xe , 1994, Nature.

[95]  G. Guillot,et al.  Low-field 3He nuclear magnetic resonance in human lungs , 1997 .

[96]  Eric A Hoffman,et al.  Mechanism of hypoxemia in acute lung injury evaluated by multidetector-row CT. , 2006, Academic radiology.

[97]  M. Reiser,et al.  ECG-gated 64-MDCT angiography in the differential diagnosis of acute chest pain. , 2007, AJR. American journal of roentgenology.

[98]  M. Reiser,et al.  Dual-source-CT in der Diagnostik des Thoraxschmerzes , 2007, Der Radiologe.

[99]  G. Peirce,et al.  Oxygen Tension of Tissues by the Polarographic Method: III. The Effect of Local Heat on the Oxygen Tension of the Skin of Extremities , 1951, Circulation.

[100]  N J Morrison,et al.  Limitations of computed tomography in the assessment of emphysema. , 1989, The American review of respiratory disease.

[101]  Milan Sonka,et al.  Image Processing, Analysis and Machine Vision , 1993, Springer US.

[102]  E. Zerhouni,et al.  Direct In Vivo Visualization of Bronchodilation Induced by Inhalational Anesthesia Using High‐resolution Computed Tomography , 1993, Anesthesiology.

[103]  E. V. van Beek,et al.  MR imaging of the lungs with hyperpolarized helium-3 gas transported by air. , 2002, Physics in medicine and biology.

[104]  Hiroto Hatabu,et al.  Hyperpolarized (129)Xe MRI: a viable functional lung imaging modality? , 2007, European journal of radiology.

[105]  C. Fink,et al.  Time-resolved echo-shared parallel MRA of the lung: observer preference study of image quality in comparison with non-echo-shared sequences , 2005, European Radiology.

[106]  A. Clough,et al.  Regional perfusion parameters from pulmonary microfocal angiograms. , 1997, The American journal of physiology.

[107]  Dmitriy A Yablonskiy,et al.  Hyperpolarized 3He diffusion MRI and histology in pulmonary emphysema , 2006, Magnetic resonance in medicine.

[108]  W. C. Ball,et al.  Regional pulmonary function studied with xenon 133. , 1962, The Journal of clinical investigation.

[109]  John P Mugler,et al.  Functional MRI of the lung using hyperpolarized 3‐helium gas , 2004, Journal of magnetic resonance imaging : JMRI.

[110]  T. Pan,et al.  Quantitative assessment of four‐dimensional computed tomography image acquisition quality , 2007, Journal of applied clinical medical physics.

[111]  John P Mugler,et al.  Imaging the lungs in asthmatic patients by using hyperpolarized helium-3 magnetic resonance: assessment of response to methacholine and exercise challenge. , 2003, The Journal of allergy and clinical immunology.

[112]  Eric A. Hoffman,et al.  Differences in regional wash-in and wash-out time constants for xenon-CT ventilation studies , 2005, Respiratory Physiology & Neurobiology.

[113]  A J Tajik,et al.  Feasibility of identifying amyloid and hypertrophic cardiomyopathy with the use of computerized quantitative texture analysis of clinical echocardiographic data. , 1989, Journal of the American College of Cardiology.

[114]  R R Edelman,et al.  Evaluation of regional pulmonary perfusion using ultrafast magnetic resonance imaging , 2001, Magnetic resonance in medicine.

[115]  D Gur,et al.  Regional Pulmonary Ventilation Measurements by Xenon Enhanced Dynamic Computed Tomography: An Update , 1981, Journal of computer assisted tomography.

[116]  M. Paley,et al.  3D volume‐localized pO2 measurement in the human lung with 3He MRI , 2005, Magnetic resonance in medicine.

[117]  N. Roewer,et al.  Anaesthetic considerations for a 2‐month‐old infant with suspected complex I respiratory chain deficiency , 2003, Paediatric anaesthesia.

[118]  Balthasar Eberle,et al.  Functional analysis in single-lung transplant recipients: a comparative study of high-resolution CT, 3He-MRI, and pulmonary function tests. , 2004, Chest.

[119]  I. Komuro,et al.  Utility of 256-slice cone beam tomography for real four-dimensional volumetric analysis without electrocardiogram gated acquisition. , 2007, International journal of cardiology.

[120]  A. Millar,et al.  Computed tomography based estimates of regional gas and tissue volume of the lung in supine subjects with chronic airflow limitation or fibrosing alveolitis. , 1986, Thorax.

[121]  J. MacFall,et al.  Hyperpolarized 3He-enhanced MR imaging of lung transplant recipients: preliminary results. , 1999, AJR. American journal of roentgenology.

[122]  M Puderbach,et al.  MR imaging of the chest: a practical approach at 1.5T. , 2007, European journal of radiology.

[123]  John P Mugler,et al.  Detection of age-dependent changes in healthy adult lungs with diffusion-weighted 3He MRI. , 2005, Academic radiology.

[124]  L. Hedlund,et al.  MR Imaging with Hyperpolarized 3He Gas , 1995, Magnetic resonance in medicine.

[125]  H. Kauczor,et al.  (3)He-MRI in follow-up of lung transplant recipients. , 2004, European radiology.

[126]  Eric A. Hoffman,et al.  Computed tomographic-based estimation of airway size with correction for scanned plane tilt angle , 2000, Medical Imaging.

[127]  Russell H. Taylor,et al.  Lung Deformation Estimation and Four-Dimensional CT Lung Reconstruction , 2005, MICCAI.

[128]  Jim M. Wild,et al.  Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry , 2007, European Radiology.

[129]  Neil Woodhouse,et al.  Emphysematous changes and normal variation in smokers and COPD patients using diffusion 3He MRI. , 2005, European journal of radiology.

[130]  G. Wang,et al.  A general cone-beam reconstruction algorithm , 1993, IEEE Trans. Medical Imaging.

[131]  A Potthast,et al.  Normal and abnormal pulmonary ventilation: visualization at hyperpolarized He-3 MR imaging. , 1996, Radiology.

[132]  L W Hedlund,et al.  In vivo He-3 MR images of guinea pig lungs. , 1996, Radiology.

[133]  T. Overton,et al.  Frequency dependence of ventilation distribution in normal and obstructed lungs. , 1977, Journal of applied physiology: respiratory, environmental and exercise physiology.

[134]  H. Kauczor,et al.  Analysis of intrapulmonary O(2) concentration by MR imaging of inhaled hyperpolarized helium-3. , 1999, Journal of applied physiology.

[135]  J. Bronzwaer,et al.  A comparison of noninvasive MRI‐based methods of estimating pulmonary artery pressure in pulmonary hypertension , 2005, Journal of magnetic resonance imaging : JMRI.

[136]  J. Hogg,et al.  Long-range diffusion of hyperpolarized 3He in explanted normal and emphysematous human lungs via magnetization tagging. , 2005, Journal of applied physiology.

[137]  Edwin J R van Beek,et al.  Dynamic radial projection MRI of inhaled hyperpolarized 3He gas , 2003, Magnetic resonance in medicine.

[138]  R H Hruban,et al.  High resolution computed tomography of inflation-fixed lungs. Pathologic-radiologic correlation of centrilobular emphysema. , 1987, The American review of respiratory disease.

[139]  Erik L. Ritman,et al.  Temporospatial Heterogeneity of Myocardial Perfusion and Blood Volume in the Porcine Heart Wall , 1998, Annals of Biomedical Engineering.

[140]  G S Lodwick,et al.  Towards computer analysis of pulmonary infiltration. , 1978, Investigative radiology.

[141]  E. Hoffman,et al.  Quantification of pulmonary emphysema from lung computed tomography images. , 1997, American journal of respiratory and critical care medicine.

[142]  S. Tanada,et al.  Superiority of synchrony of 256-slice cone beam computed tomography for acquiring pulsating objects. Comparison with conventional multislice computed tomography. , 2007, International journal of cardiology.

[143]  M. Viallon,et al.  A combined 1H perfusion/3He ventilation NMR study in rat lungs , 1999, Magnetic resonance in medicine.

[144]  Jie Zheng,et al.  Feasibility of combining MR perfusion, angiography, and 3He ventilation imaging for evaluation of lung function in a porcine model. , 2005, Academic radiology.

[145]  Eric A Hoffman,et al.  Subsecond multisection CT of regional pulmonary ventilation. , 2002, Academic radiology.

[146]  J. Tomashefski SEMINARS IN RESPIRATORY MEDICINE , 1980 .

[147]  J. Newell,et al.  Expiratory computed tomography for assessment of suspected pulmonary emphysema. , 1991, Chest.

[148]  D. Gur,et al.  Local lung ventilation in critically ill patients using nonradioactive xenon‐enhanced transmission computed tomography , 1984, Critical care medicine.

[149]  Eike Rietzel,et al.  Deformable registration of 4D computed tomography data. , 2006, Medical physics.

[150]  Johan H C Reiber,et al.  Variability in Densitometric Assessment of Pulmonary Emphysema With Computed Tomography , 2005, Investigative radiology.

[151]  E L Ritman,et al.  Measurement of renal perfusion and blood flow with fast computed tomography. , 1994, Circulation research.

[152]  N J Morrison,et al.  Quantitation of emphysema by computed tomography using a "density mask" program and correlation with pulmonary function tests. , 1990, Chest.

[153]  S. M. Collins,et al.  Quantitative texture analysis in two-dimensional echocardiography: application to the diagnosis of experimental myocardial contusion. , 1983, Circulation.

[154]  A R Sovijärvi,et al.  Quantitative functional lung imaging with synchrotron radiation using inhaled xenon as contrast agent. , 2001, Physics in medicine and biology.

[155]  G. Topulos,et al.  3He lung imaging in an open access, very‐low‐field human magnetic resonance imaging system , 2005, Magnetic resonance in medicine.

[156]  Kunihiro Yagihashi,et al.  Quantitative Assessment of Peripheral Airway Obstruction on Paired Expiratory/Inspiratory Thin-section Computed Tomography in Chronic Obstructive Pulmonary Disease With Emphysema , 2007, Journal of computer assisted tomography.

[157]  Milan Sonka,et al.  Quantitative analysis of pulmonary airway tree structures , 2006, Comput. Biol. Medicine.

[158]  W. Wagner,et al.  Comparison of direct and indirect measurements of pulmonary capillary transit times. , 1987, Journal of applied physiology.

[159]  Steven D. Kugelmass,et al.  Matching pulmonary structure and perfusion via combined dynamic multislice CT and thin-slice high-resolution CT. , 1995, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[160]  Milan Sonka,et al.  Intrathoracic airway trees: segmentation and airway morphology analysis from low-dose CT scans , 2005, IEEE Transactions on Medical Imaging.

[161]  Yannick Crémillieux,et al.  Dynamic 3He imaging for quantification of regional lung ventilation parameters , 2003, Magnetic resonance in medicine.

[162]  W A Kalender,et al.  Standardized quantitative high resolution CT in lung diseases. , 1991, Journal of computer assisted tomography.

[163]  W. Webb,et al.  Dynamic Quantitative Computed Tomography: A Predictor of Pulmonary Function in Obstructive Lung Diseases , 1994, Investigative radiology.

[164]  J M Keller,et al.  Automatic Outlining of Regions on CT Scans , 1981, Journal of computer assisted tomography.

[165]  B Bunow,et al.  Regional ventilatory clearance by xenon scintigraphy: a critical evaluation of two estimation procedures. , 1979, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[166]  A T Redpath,et al.  Parenchymal emphysema measured by CT lung density correlates with lung function in patients with bullous disease. , 1993, The European respiratory journal.

[167]  Sean B Fain,et al.  Early emphysematous changes in asymptomatic smokers: detection with 3He MR imaging. , 2006, Radiology.

[168]  Kazuyoshi Suga,et al.  Technical and analytical advances in pulmonary ventilation SPECT with xenon-133 gas and Tc-99m-Technegas , 2002, Annals of nuclear medicine.

[169]  Jörg Schmiedeskamp,et al.  Diffusion‐weighted MRI of the lung with hyperpolarized helium‐3: A study of reproducibility , 2005, Journal of magnetic resonance imaging : JMRI.

[170]  R R Edelman,et al.  Quantitative assessment of pulmonary perfusion with dynamic contrast‐enhanced MRI , 1999, Magnetic resonance in medicine.

[171]  Jim M. Wild,et al.  Feasibility of Image Registration and Intensity-Modulated Radiotherapy Planning With Hyperpolarized Helium-3 Magnetic Resonance Imaging for Non–Small-Cell Lung Cancer , 2007, International journal of radiation oncology, biology, physics.

[172]  H C Charles,et al.  Human lung air spaces: potential for MR imaging with hyperpolarized He-3. , 1996, Radiology.

[173]  R. Günther,et al.  Multislice computed tomography perfusion imaging for visualization of acute pulmonary embolism: animal experience , 2005, European Radiology.

[174]  J A Merchant,et al.  High-resolution CT-derived measures of lung density are valid indexes of interstitial lung disease. , 1994, Journal of applied physiology.

[175]  P. Boesiger,et al.  SENSE: Sensitivity encoding for fast MRI , 1999, Magnetic resonance in medicine.

[176]  E. Beek,et al.  MR imaging of the pulmonary vasculature—an update , 2006, European Radiology.

[177]  E. V. van Beek,et al.  Computer-aided classification of interstitial lung diseases via MDCT: 3D adaptive multiple feature method (3D AMFM). , 2006, Academic radiology.

[178]  C. Marcucci,et al.  A1089 REGIONAL DIFFERENCES IN VOLUME RECRUITMENT AND VENTILATION IN DOGS AFTER ACUTE LUNG INJURY (ALI) , 1997 .

[179]  E. V. van Beek,et al.  The Comprehensive Imaging-Based Analysis of the Lung : A Forum for Team Science 1 , 2004 .

[180]  John P Mugler,et al.  Emphysema: hyperpolarized helium 3 diffusion MR imaging of the lungs compared with spirometric indexes--initial experience. , 2002, Radiology.

[181]  Eric A. Hoffman,et al.  Xenon-enhanced CT imaging of local pulmonary ventilation , 1996, Medical Imaging.

[182]  E. Hoffman,et al.  Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function. , 2003, Academic radiology.

[183]  Milan Sonka,et al.  Matching and anatomical labeling of human airway tree , 2005, IEEE Transactions on Medical Imaging.

[184]  N. Müller,et al.  "Density mask". An objective method to quantitate emphysema using computed tomography. , 1988, Chest.

[185]  Yasutaka Nakano,et al.  The prediction of small airway dimensions using computed tomography. , 2005, American journal of respiratory and critical care medicine.

[186]  H. Kauczor,et al.  3He MRI in healthy volunteers: preliminary correlation with smoking history and lung volumes , 2000, NMR in biomedicine.

[187]  B C Stoel,et al.  Validation of computed tomographic lung densitometry for monitoring emphysema in α1-antitrypsin deficiency , 2006, Thorax.

[188]  Derliz Mereles,et al.  Quantitative 3D pulmonary MR-perfusion in patients with pulmonary arterial hypertension: correlation with invasive pressure measurements. , 2007, European journal of radiology.

[189]  E A Hoffman,et al.  Assessment of methacholine-induced airway constriction by ultrafast high-resolution computed tomography. , 1993, Journal of applied physiology.

[190]  E A Hoffman,et al.  Measurement of three-dimensional lung tree structures by using computed tomography. , 1995, Journal of applied physiology.

[191]  T L Chenevert,et al.  Diagnosis of pulmonary embolism with magnetic resonance angiography. , 1997, The New England journal of medicine.

[192]  M. Mintun,et al.  Quantitative measurement of regional pulmonary blood flow with positron emission tomography. , 1986, Journal of applied physiology.

[193]  D. Flenley,et al.  Pulmonary hemodynamics, gas exchange, and the severity of emphysema as assessed by quantitative CT scan in chronic bronchitis and emphysema. , 1989, The American review of respiratory disease.

[194]  Stephen Lam,et al.  The effects of radiation dose and CT manufacturer on measurements of lung densitometry. , 2007, Chest.

[195]  Geoffrey McLennan,et al.  State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease. , 2006, Proceedings of the American Thoracic Society.

[196]  Lise Vejby Søgaard,et al.  Assessment of lung microstructure with magnetic resonance imaging of hyperpolarized Helium-3 , 2005, Respiratory Physiology & Neurobiology.

[197]  I. Weir Coronary artery stenosis. , 2006, Annals of the Royal College of Surgeons of England.

[198]  G. Miller,et al.  Time dependence of 3He diffusion in the human lung: Measurement in the long‐time regime using stimulated echoes , 2006, Magnetic resonance in medicine.

[199]  John P Mugler,et al.  Assessment of lung development using hyperpolarized helium‐3 diffusion MR imaging , 2006, Journal of magnetic resonance imaging : JMRI.

[200]  Rainer Raupach,et al.  Dose performance of a 64-channel dual-source CT scanner. , 2007, Radiology.

[201]  D. Yablonskiy,et al.  MR imaging of diffusion of 3He gas in healthy and diseased lungs , 2000, Magnetic resonance in medicine.