论文信息 - Web based brain volume calculation for magnetic resonance images

Web based brain volume calculation for magnetic resonance images

Brain volume calculations are crucial in modern medical research, especially in the study of neurodevelopmental disorders. In this paper, we present an algorithm for calculating two classifications of brain volume, total brain volume (TBV) and intracranial volume (ICV). Our algorithm takes MRI data as input, performs several preprocessing and intermediate steps, and then returns each of the two calculated volumes. To simplify this process and make our algorithm publicly accessible to anyone, we have created a web-based interface that allows users to upload their own MRI data and calculate the TBV and ICV for the given data. This interface provides a simple and efficient method for calculating these two classifications of brain volume, and it also removes the need for the user to download or install any applications.

[1] David J. David,et al. Intracranial volume measurement of sagittal craniosynostosis , 2007, Journal of Clinical Neuroscience.

[2] Paul M. Thompson,et al. Detection and mapping of hippocampal abnormalities in autism , 2006, Psychiatry Research: Neuroimaging.

[3] Mark W. Woolrich,et al. Advances in functional and structural MR image analysis and implementation as FSL , 2004, NeuroImage.

[4] Stephen M Smith,et al. Fast robust automated brain extraction , 2002, Human brain mapping.

[5] Frithjof Kruggel,et al. The relationship between head size and intracranial volume in elderly subjects , 2003, Brain Research.

[6] Amar Gajjar,et al. Decline in corpus callosum volume among pediatric patients with medulloblastoma: longitudinal MR imaging study. , 2002, AJNR. American journal of neuroradiology.

[7] J. Piven,et al. Magnetic resonance imaging and head circumference study of brain size in autism: birth through age 2 years. , 2005, Archives of general psychiatry.

[8] C. Rorden,et al. Stereotaxic display of brain lesions. , 2000, Behavioural neurology.

[9] Paul M. Thompson,et al. Mapping Corpus Callosum Deficits in Autism: An Index of Aberrant Cortical Connectivity , 2006, Biological Psychiatry.

[10] Nikos Makris,et al. Adjustment for whole brain and cranial size in volumetric brain studies: a review of common adjustment factors and statistical methods. , 2006, Harvard review of psychiatry.