The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis

[1]  Jessica L. Henty-Ridilla.  Visualizing Actin and Microtubule Coupling Dynamics In Vitro by Total Internal Reflection Fluorescence (TIRF) Microscopy , 2022, Journal of visualized experiments : JoVE.

[2]  Xinbei Liu,et al.  Visualizing molecules of functional human profilin , 2022, bioRxiv.

[3]  B. Haarer,et al.  Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants , 2022, bioRxiv.

[4]  S. Sidhu,et al.  USP10 Promotes Fibronectin Recycling, Secretion, and Organization , 2021, Investigative ophthalmology & visual science.

[5]  S. Macdonald,et al.  Emerging therapeutic opportunities for integrin inhibitors , 2021, Nature reviews. Drug discovery.

[6]  D. Müller,et al.  Correction: αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation , 2020, The Journal of cell biology.

[7]  D. Müller,et al.  αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation , 2020, The Journal of cell biology.

[8]  A. Wolfson,et al.  USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea , 2020, Molecular therapy. Nucleic acids.

[9]  Kenneth M. Yamada,et al.  Characterization of stitch adhesions: Fibronectin-containing cell-cell contacts formed by fibroblasts. , 2019, Experimental cell research.

[10]  P. Cidad,et al.  Dynamic changes of the extracellular matrix during corneal wound healing. , 2019, Experimental eye research.

[11]  M. Kloc,et al.  Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis , 2019, PloS one.

[12]  Nileyma Castro,et al.  Ex Vivo Corneal Organ Culture Model for Wound Healing Studies. , 2019, Journal of visualized experiments : JoVE.

[13]  B. Hinz,et al.  The big five in fibrosis: Macrophages, myofibroblasts, matrix, mechanics, and miscommunication. , 2018, Matrix biology : journal of the International Society for Matrix Biology.

[14]  L. Lassance,et al.  Fibrocyte migration, differentiation and apoptosis during the corneal wound healing response to injury , 2018, Experimental eye research.

[15]  J. de Rooij,et al.  Vps3 and Vps8 control integrin trafficking from early to recycling endosomes and regulate integrin-dependent functions , 2018, Nature Communications.

[16]  K. Takayama,et al.  Association of USP10 with G3BP2 Inhibits p53 Signaling and Contributes to Poor Outcome in Prostate Cancer , 2018, Molecular Cancer Research.

[17]  Florent Ubelmann,et al.  Measuring the Endocytic Recycling of Amyloid Precursor Protein (APP) in Neuro2a Cells. , 2017, Bio-protocol.

[18]  Daisy Y. Shu,et al.  Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis , 2017, Progress in Retinal and Eye Research.

[19]  W. DeGrado,et al.  Pharmacologic Blockade of αvβ1 Integrin Ameliorates Renal Failure and Fibrosis In Vivo. , 2017, Journal of the American Society of Nephrology : JASN.

[20]  D. Komander,et al.  Mechanisms of Deubiquitinase Specificity and Regulation. , 2017, Annual review of biochemistry.

[21]  Steven E. Wilson,et al.  Injury and defective regeneration of the epithelial basement membrane in corneal fibrosis: A paradigm for fibrosis in other organs? , 2017, Matrix biology : journal of the International Society for Matrix Biology.

[22]  C. Cursiefen,et al.  Wound-Healing Studies in Cornea and Skin: Parallels, Differences and Opportunities , 2017, International journal of molecular sciences.

[23]  G. Washko,et al.  Genome-wide association study of subclinical interstitial lung disease in MESA , 2017, Respiratory Research.

[24]  Hisayuki Tsukuma,et al.  Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH) , 2017, Diagnostic Pathology.

[25]  N. Beerenwinkel,et al.  αV-class integrins exert dual roles on α5β1 integrins to strengthen adhesion to fibronectin , 2017, Nature Communications.

[26]  M. Takeichi,et al.  DAAM1 stabilizes epithelial junctions by restraining WAVE complex–dependent lateral membrane motility , 2016, The Journal of cell biology.

[27]  T. Ridky,et al.  The integrin αv-TGFβ signaling axis is necessary for epidermal proliferation during cutaneous wound healing , 2016, Cell cycle.

[28]  G. Westergren-Thorsson,et al.  Aberrant nonfibrotic parenchyma in idiopathic pulmonary fibrosis is correlated with decreased β‐catenin inhibition and increased Wnt5a/b interaction , 2016, Physiological reports.

[29]  Elizabeth Cook,et al.  Expression of WNT5A in Idiopathic Pulmonary Fibrosis and Its Control by TGF-β and WNT7B in Human Lung Fibroblasts , 2016, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[30]  F. Malecaze,et al.  Collagens and proteoglycans of the cornea: importance in transparency and visual disorders , 2016, Cell and Tissue Research.

[31]  W. DeGrado,et al.  The αvβ1 integrin plays a critical in vivo role in tissue fibrosis , 2015, Science Translational Medicine.

[32]  G. Müller,et al.  Primary cilia modulate balance of canonical and non-canonical Wnt signaling responses in the injured kidney , 2015, Fibrogenesis & tissue repair.

[33]  S. Corbett,et al.  The fate of internalized α5 integrin is regulated by matrix-capable fibronectin. , 2014, The Journal of surgical research.

[34]  B. Hinz,et al.  Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction. , 2014, Cardiovascular research.

[35]  U. Landegren,et al.  Sensitivity and Specificity of In situ Proximity Ligation for Protein Interaction Analysis in a Model of Steatohepatitis with Mallory-Denk Bodies , 2014, PloS one.

[36]  V. Trinkaus-Randall,et al.  Wounding the cornea to learn how it heals. , 2014, Experimental eye research.

[37]  R. Shao,et al.  Downregulation of G3BPs inhibits the growth, migration and invasion of human lung carcinoma H1299 cells by suppressing the Src/FAK-associated signaling pathway , 2013, Cancer Gene Therapy.

[38]  A. Hutcheon,et al.  Role of thrombospondin-1 in repair of penetrating corneal wounds. , 2013, Investigative ophthalmology & visual science.

[39]  D. Breitsprecher,et al.  The Formin Daam1 and Fascin Directly Collaborate to Promote Filopodia Formation , 2013, Current Biology.

[40]  R. Fässler,et al.  Mechanosensitivity and compositional dynamics of cell–matrix adhesions , 2013, EMBO reports.

[41]  W. Rappel,et al.  Alignment of cellular motility forces with tissue flow as a mechanism for efficient wound healing , 2013, Proceedings of the National Academy of Sciences.

[42]  D. Griggs,et al.  OC-001 The Impact of the Introduction of Formalised Polypectomy Assessment on Training in the United Kingdom , 2013, Gut.

[43]  J. Norman,et al.  Integrin trafficking at a glance , 2012, Journal of Cell Science.

[44]  Johannes E. Schindelin,et al.  Fiji: an open-source platform for biological-image analysis , 2012, Nature Methods.

[45]  L. Blanchoin,et al.  Structure and activity of full‐length formin mDia1 , 2012, Cytoskeleton.

[46]  S. Wilson.  Corneal myofibroblast biology and pathobiology: generation, persistence, and transparency. , 2012, Experimental eye research.

[47]  Jun Du,et al.  Dvl2-Dependent Activation of Daam1 and RhoA Regulates Wnt5a-Induced Breast Cancer Cell Migration , 2012, PloS one.

[48]  D. Sheppard,et al.  Cross talk among TGF-β signaling pathways, integrins, and the extracellular matrix. , 2011, Cold Spring Harbor perspectives in biology.

[49]  N. Dulin,et al.  Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function. , 2011, Translational research : the journal of laboratory and clinical medicine.

[50]  A. Hutcheon,et al.  αVβ6 integrin promotes corneal wound healing. , 2011, Investigative ophthalmology & visual science.

[51]  A. Huttenlocher,et al.  Integrins in cell migration. , 2011, Cold Spring Harbor perspectives in biology.

[52]  H. Stenmark,et al.  Ubiquitination of α-integrin cytoplasmic tails , 2010, Communicative & integrative biology.

[53]  C. Crews,et al.  Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis , 2010, Proceedings of the National Academy of Sciences.

[54]  J. Cheville,et al.  USP10 Regulates p53 Localization and Stability by Deubiquitinating p53 , 2010, Cell.

[55]  P. Friedl,et al.  Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms , 2009, Cell and Tissue Research.

[56]  David Komander,et al.  Breaking the chains: structure and function of the deubiquitinases , 2009, Nature Reviews Molecular Cell Biology.

[57]  J. Bomberger,et al.  The Deubiquitinating Enzyme USP10 Regulates the Post-endocytic Sorting of Cystic Fibrosis Transmembrane Conductance Regulator in Airway Epithelial Cells* , 2009, The Journal of Biological Chemistry.

[58]  D. Wirtz,et al.  The filamentous actin cross-linking/bundling activity of mammalian formins. , 2008, Journal of molecular biology.

[59]  A. Sonnenberg,et al.  Binding of soluble fibronectin to integrin α5β1 – link to focal adhesion redistribution and contractile shape , 2008, Journal of Cell Science.

[60]  W. Seeger,et al.  Functional Wnt Signaling Is Increased in Idiopathic Pulmonary Fibrosis , 2008, PloS one.

[61]  R. Habas,et al.  Mechanism of activation of the Formin protein Daam1 , 2008, Proceedings of the National Academy of Sciences.

[62]  Giorgio Scita,et al.  Novel Roles of Formin mDia2 in Lamellipodia and Filopodia Formation in Motile Cells , 2007, PLoS biology.

[63]  A. Bernstein,et al.  Urokinase receptor cleavage: a crucial step in fibroblast-to-myofibroblast differentiation. , 2007, Molecular biology of the cell.

[64]  P. Aspenström,et al.  The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics. , 2006, Experimental cell research.

[65]  M. Eck,et al.  Structure of the autoinhibitory switch in formin mDia1. , 2006, Structure.

[66]  M. Jinnin,et al.  Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts , 2006 .

[67]  J. Schwarzbauer,et al.  Fibronectin fibrillogenesis, a cell-mediated matrix assembly process. , 2005, Matrix biology : journal of the International Society for Matrix Biology.

[68]  H. Higgs.  Formin proteins: a domain-based approach. , 2005, Trends in biochemical sciences.

[69]  R. Chanet,et al.  Protein interaction mapping: a Drosophila case study. , 2005, Genome research.

[70]  J. Schwarzbauer,et al.  Analysis of Fibronectin Matrix Assembly , 2004, Current protocols in cell biology.

[71]  H. Higgs,et al.  Phylogenetic analysis of the formin homology 2 domain. , 2004, Molecular biology of the cell.

[72]  Mark P. Lewis,et al.  αv integrins play an important role in myofibroblast differentiation , 2004, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[73]  Arnoud Sonnenberg,et al.  Integrins in regulation of tissue development and function , 2003, The Journal of pathology.

[74]  R. Day,et al.  Myofibroblast Differentiation by Transforming Growth Factor-β1 Is Dependent on Cell Adhesion and Integrin Signaling via Focal Adhesion Kinase* , 2003, The Journal of Biological Chemistry.

[75]  Pierre Legrain,et al.  Prediction, assessment and validation of protein interaction maps in bacteria. , 2002, Journal of molecular biology.

[76]  J. Wojcik,et al.  The protein–protein interaction map of Helicobacter pylori , 2001, Nature.

[77]  J. Schwarzbauer,et al.  Fibronectin fibrillogenesis: a paradigm for extracellular matrix assembly. , 1999, Current opinion in cell biology.

[78]  K. Fujiwara,et al.  Isolation and contraction of the stress fiber. , 1998, Molecular biology of the cell.

[79]  R. Stein,et al.  Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes. , 1998, Biochemistry.

[80]  P. Legrain,et al.  Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens , 1997, Nature Genetics.

[81]  I. Duncan,et al.  Microtubule Organization and Stability in the Oligodendrocyte , 1997, The Journal of Neuroscience.

[82]  S. Aresta,et al.  Getting more from the two-hybrid system: N-terminal fusions to LexA are efficient and sensitive baits for two-hybrid studies. , 1997, Nucleic acids research.

[83]  S. Fields,et al.  Use of the two-hybrid system to identify the domain of p53 involved in oligomerization. , 1993, Oncogene.

[84]  S. Fields,et al.  Elimination of false positives that arise in using the two-hybrid system. , 1993, BioTechniques.

[85]  B. Hinz,et al.  Immunofluorescence detection of the cytoskeleton and extracellular matrix in tissue and cultured cells. , 2010, Methods in molecular biology.

[86]  Nicola J. Rinaldi,et al.  Partial Inhibition of Integrin αvβ6 Prevents Pulmonary Fibrosis without Exacerbating Inflammation , 2008 .

[87]  M. Srinivasan,et al.  Corneal blindness: a global perspective. , 2001, Bulletin of the World Health Organization.

[88]  A. Desmoulière,et al.  Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. , 1995, The American journal of pathology.

[89]  A. Vojtek,et al.  Ras-Raf interaction: two-hybrid analysis. , 1995, Methods in enzymology.