The regulatory role of nitric oxide in apoptosis.

[1]  S Moncada,et al.  The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival or death. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[2]  D. K. Kuharsky,et al.  Bid-induced Cytochrome c Release Is Mediated by a Pathway Independent of Mitochondrial Permeability Transition Pore and Bax* , 2000, The Journal of Biological Chemistry.

[3]  M. Trucco,et al.  Protection of Human Islets from the Effects of Interleukin-1β by Adenoviral Gene Transfer of an IκB Repressor* , 2000, The Journal of Biological Chemistry.

[4]  John Savill,et al.  Corpse clearance defines the meaning of cell death , 2000, Nature.

[5]  Rachel L. Allen,et al.  Defying death after DNA damage , 2000, Nature.

[6]  M. Hengartner.  The biochemistry of apoptosis , 2000, Nature.

[7]  G. Brown,et al.  Nitric‐Oxide‐Induced Necrosis and Apoptosis in PC12 Cells Mediated by Mitochondria , 2000, Journal of neurochemistry.

[8]  B. Roos,et al.  Gene therapy of rat medullary thyroid cancer by naked nitric oxide synthase II DNA injection , 2000, The journal of gene medicine.

[9]  A. Zeiher,et al.  Nitric Oxide Down-regulates MKP-3 mRNA Levels , 2000, The Journal of Biological Chemistry.

[10]  K. Kobayashi,et al.  A common downstream signaling activity of osteoclast survival factors that prevent nitric oxide-promoted osteoclast apoptosis. , 2000, Endocrinology.

[11]  H. Ford,et al.  Nitric Oxide Induces Thymocyte Apoptosis Via a Caspase-1-Dependent Mechanism1 , 2000, The Journal of Immunology.

[12]  T. Ogihara,et al.  Negative feedback regulation of activated macrophages via Fas-mediated apoptosis. , 2000, American journal of physiology. Cell physiology.

[13]  A. Moran,et al.  Cytotoxicity associated with induction of nitric oxide synthase in rat duodenal epithelial cells in vivo by lipopolysaccharide of Helicobacter pylori: inhibition by superoxide dismutase , 2000, British journal of pharmacology.

[14]  W. Hawthorne,et al.  Inducible nitric oxide synthetase is expressed in adult but not fetal pig pancreatic islets , 2000, Xenotransplantation.

[15]  D. Green.  Apoptotic Pathways Paper Wraps Stone Blunts Scissors , 2000, Cell.

[16]  S. Pham,et al.  FK409, a spontaneous nitric oxide releaser, attenuates allograft vasculopathy in a rat aortic transplant model. , 2000, Circulation research.

[17]  B. Freeman,et al.  Concentration-dependent Effects of Nitric Oxide on Mitochondrial Permeability Transition and Cytochrome cRelease* , 2000, The Journal of Biological Chemistry.

[18]  Robert L Moritz,et al.  Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins , 2000, Cell.

[19]  Simon C Watkins,et al.  Expression of inducible nitric oxide synthase and interleukin-12 in experimental necrotizing enterocolitis. , 2000, The Journal of surgical research.

[20]  Y. Asano,et al.  Erythropoietin regulates vascular smooth muscle cell apoptosis by a phosphatidylinositol 3 kinase-dependent pathway. , 2000, Kidney international.

[21]  M. Goldberg,et al.  Oxygen-glucose deprivation induces inducible nitric oxide synthase and nitrotyrosine expression in cerebral endothelial cells. , 2000, Stroke.

[22]  H. Nishimatsu,et al.  Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism. , 2000, Hypertension.

[23]  J. Loscalzo,et al.  Nitric oxide induces apoptosis in megakaryocytic cell lines. , 2000, Blood.

[24]  J. Borowitz,et al.  Dopamine‐Induced Apoptosis Is Mediated by Oxidative Stress and Is Enhanced by Cyanide in Differentiated PC12 Cells , 2000, Journal of neurochemistry.

[25]  H. Akil,et al.  Direct evidence of nitric oxide presence within mitochondria. , 2000, Biochemical and biophysical research communications.

[26]  E. Clementi,et al.  Nitric oxide inhibits tumor necrosis factor-alpha-induced apoptosis by reducing the generation of ceramide. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[27]  B. Holzmann,et al.  Critical role of nitric oxide for proliferation and apoptosis of bone-marrow cells under septic conditions , 2000, Annals of Hematology.

[28]  J. Laman,et al.  Functional and in situ evidence for nitric oxide production driven by CD40-CD40L interactions in graft-versus-leukemia reactivity. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[29]  T. Billiar,et al.  Cyclic Nucleotides Suppress Tumor Necrosis Factor α-Mediated Apoptosis by Inhibiting Caspase Activation and Cytochrome cRelease in Primary Hepatocytes via a Mechanism Independent of Akt Activation* , 2000, The Journal of Biological Chemistry.

[30]  A. Boveris,et al.  Nitric oxide production and mitochondrial dysfunction during rat thymocyte apoptosis. , 2000, Archives of biochemistry and biophysics.

[31]  T. Billiar,et al.  Cellular Non-heme Iron Content Is a Determinant of Nitric Oxide-mediated Apoptosis, Necrosis, and Caspase Inhibition* , 2000, The Journal of Biological Chemistry.

[32]  F. Sigaux,et al.  Expression of a functional inducible nitric oxide synthase in hairy cell leukaemia and ESKOL cell line , 2000, Leukemia.

[33]  R. Coppo,et al.  Nitric oxide mediates cyclosporine-induced apoptosis in cultured renal cells. , 2000, Kidney international.

[34]  B. Boulanger,et al.  Trauma increases extrahepatic arginase activity. , 2000, Surgery.

[35]  R. Linden.  The anti-death league: associative control of apoptosis in developing retinal tissue , 2000, Brain Research Reviews.

[36]  P. Thompson,et al.  Nitrite generation and antioxidant effects during neutrophil apoptosis. , 2000, Free radical biology & medicine.

[37]  D. Fradelizi,et al.  Protective effect of thioredoxin upon NO-mediated cell injury in THP1 monocytic human cells. , 2000, The Biochemical journal.

[38]  C. Prinz,et al.  IL-1β–Induced apoptosis in rat gastric enterochromaffin-like cells is mediated by iNOS, NF-κB, and Bax protein , 2000 .

[39]  G. Rotilio,et al.  Cu,Zn-Superoxide Dismutase-dependent Apoptosis Induced by Nitric Oxide in Neuronal Cells* , 2000, The Journal of Biological Chemistry.

[40]  J. Duffield,et al.  Activated Macrophages Direct Apoptosis and Suppress Mitosis of Mesangial Cells1 , 2000, The Journal of Immunology.

[41]  C. L. Potter,et al.  Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cells , 2000, Gut.

[42]  A. Zeiher,et al.  Inhibition of endogenous nitric oxide synthase potentiates ischemia-reperfusion-induced myocardial apoptosis via a caspase-3 dependent pathway. , 2000, Cardiovascular research.

[43]  L. Barbeito,et al.  Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal. , 2000, Free radical biology & medicine.

[44]  Sumio Watanabe,et al.  Helicobacter pylori induces apoptosis in gastric epithelial cells through inducible nitric oxide , 2000, Journal of gastroenterology and hepatology.

[45]  Xiangru Lu,et al.  Tumor necrosis factor-α induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes , 2000 .

[46]  H. Piper,et al.  Apoptosis induction by nitric oxide in adult cardiomyocytes via cGMP-signaling and its impairment after simulated ischemia. , 2000, Cardiovascular Research.

[47]  K. Utsumi,et al.  Caspase activation and cytochrome c release during HL-60 cell apoptosis induced by a nitric oxide donor , 2000, Free radical research.

[48]  D. Hougaard,et al.  Endogenous Endothelial Cell Nitric-oxide Synthase Modulates Apoptosis in Cultured Breast Cancer Cells and Is Transcriptionally Regulated by p53* , 1999, The Journal of Biological Chemistry.

[49]  K. Teng,et al.  Activation of c-Ha-Ras by Nitric Oxide Modulates Survival Responsiveness in Neuronal PC12 Cells* , 1999, The Journal of Biological Chemistry.

[50]  J S Beckman,et al.  Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. , 1999, Science.

[51]  A. Álvarez,et al.  Nitric oxide induces tyrosine nitration and release of cytochrome c preceding an increase of mitochondrial transmembrane potential in macrophages , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[52]  P. Debré,et al.  Critical Role of Nitric Oxide During the Apoptosis of Peripheral Blood Leukocytes from Patients with AIDS , 1999, Molecular medicine.

[53]  G. Melino,et al.  Regulation of Transglutaminases by Nitric Oxide , 1999, Annals of the New York Academy of Sciences.

[54]  G. Kroemer,et al.  Mitochondrial Membrane Permeabilization during the Apoptotic Process , 1999, Annals of the New York Academy of Sciences.

[55]  T. Klockgether,et al.  Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase , 1999, Journal of Neuroimmunology.

[56]  P. Singhal,et al.  Ethanol‐induced neutrophil apoptosis is mediated through nitric oxide , 1999, Journal of leukocyte biology.

[57]  B. Brüne,et al.  p53 accumulation in apoptotic macrophages is an energy demanding process that precedes cytochrome c release in response to nitric oxide , 1999, Oncogene.

[58]  H. Pae,et al.  Apoptotic cell death induced by taxol is inhibited by nitric oxide in human leukemia HL-60 cells. , 1999, Immunopharmacology and immunotoxicology.

[59]  Jen-kun Lin,et al.  Induction of apoptosis by S‐Nitrosoglutathione and Cu2+ or Ni2+ ion through modulation of bax, bad, and bcl‐2 proteins in human colon adenocarcinoma cells , 1999, Molecular carcinogenesis.

[60]  Shing-Hwa Liu,et al.  Nitric oxide prevents apoptosis of human endothelial cells from high glucose exposure during early stage , 1999, Journal of cellular biochemistry.

[61]  C. Richter,et al.  Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation. , 1999, The Journal of biological chemistry.

[62]  J. Beckman.  Parsing the effects of nitric oxide, S-nitrosothiols, and peroxynitrite on inducible nitric oxide synthase-dependent cardiac myocyte apoptosis. , 1999, Circulation research.

[63]  C. Ferran,et al.  A20 Inhibits Cytokine-Induced Apoptosis and Nuclear Factor κB–Dependent Gene Activation in Islets , 1999, The Journal of experimental medicine.

[64]  A. Allione,et al.  Nitric oxide suppresses human T lymphocyte proliferation through IFN-gamma-dependent and IFN-gamma-independent induction of apoptosis. , 1999, Journal of immunology.

[65]  Xueliang Du,et al.  Generation of reactive oxygen intermediates, activation of NF-κB, and induction of apoptosis in human endothelial cells by glucose: role of nitric oxide synthase? , 1999 .

[66]  B. Brüne,et al.  NO-Evoked Macrophage Apoptosis Is Attenuated by cAMP-Induced Gene Expression , 1999, Molecular medicine.

[67]  T. Billiar,et al.  The anti-apoptotic actions of nitric oxide in hepatocytes , 1999, Cell Death and Differentiation.

[68]  A. Khar,et al.  Induction of nitric oxide production by natural killer cells: its role in tumor cell death. , 1999, Nitric oxide : biology and chemistry.

[69]  B. Brüne,et al.  Protection against nitric oxide-induced apoptosis in rat mesangial cells demands mitogen-activated protein kinases and reduced glutathione. , 1999, Molecular pharmacology.

[70]  H. Mühl,et al.  Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells , 1999, European journal of immunology.

[71]  K. Isobe,et al.  Mitogen-activated protein kinase pathway mediates peroxynitrite-induced apoptosis in human dopaminergic neuroblastoma SH-SY5Y cells. , 1999, Biochemical and biophysical research communications.

[72]  J. Fortenberry,et al.  Effects of exogenous nitric oxide and hyperoxia on lung fibroblast viability and DNA fragmentation. , 1999, Biochemical and biophysical research communications.

[73]  P. Cannon,et al.  Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture. , 1999, American journal of physiology. Heart and circulatory physiology.

[74]  T. Billiar,et al.  Nitric Oxide Protects PC12 Cells from Serum Deprivation-Induced Apoptosis by cGMP-Dependent Inhibition of Caspase Signaling , 1999, The Journal of Neuroscience.

[75]  P. Burd,et al.  Human NK cells express endothelial nitric oxide synthase, and nitric oxide protects them from activation-induced cell death by regulating expression of TNF-alpha. , 1999, Journal of immunology.

[76]  A. Rebollo,et al.  Novel aspects of Ras proteins biology: regulation and implications , 1999, Cell Death and Differentiation.

[77]  S. Back,et al.  Intracellular Redox State Determines Whether Nitric Oxide Is Toxic or Protective to Rat Oligodendrocytes in Culture , 1999, Journal of neurochemistry.

[78]  M. Wilm,et al.  Mass Spectrometric Analysis of Nitric Oxide-modified Caspase-3* , 1999, The Journal of Biological Chemistry.

[79]  M. Scheffner,et al.  Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the Proteasome* , 1999, The Journal of Biological Chemistry.

[80]  M. Broillet.  S-Nitrosylation of proteins , 1999, Cellular and Molecular Life Sciences CMLS.

[81]  T. Gotoh,et al.  Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide. , 1999, American journal of physiology. Endocrinology and metabolism.

[82]  T. Billiar,et al.  Nitric Oxide Suppresses Apoptosis via Interrupting Caspase Activation and Mitochondrial Dysfunction in Cultured Hepatocytes* , 1999, The Journal of Biological Chemistry.

[83]  T. Billiar,et al.  Nitric‐oxide production by murine mammary adenocarcinoma cells promotes tumor‐cell invasiveness , 1999, International journal of cancer.

[84]  A. Neufeld,et al.  Nitric oxide: a potential mediator of retinal ganglion cell damage in glaucoma. , 1999, Survey of ophthalmology.

[85]  E. Clementi,et al.  The p75NTR-induced Apoptotic Program Develops through a Ceramide-Caspase Pathway Negatively Regulated by Nitric Oxide* , 1999, The Journal of Biological Chemistry.

[86]  S. Paik,et al.  Modulation of nitric oxide-induced apoptotic death of HL-60 cells by protein kinase C and protein kinase A through mitogen-activated protein kinases and CPP32-like protease pathways. , 1999, Cellular immunology.

[87]  G. Brown,et al.  Nitric oxide and mitochondrial respiration. , 1999, Biochimica et biophysica acta.

[88]  M. Lotz,et al.  The role of nitric oxide in articular cartilage damage. , 1999, Rheumatic diseases clinics of North America.

[89]  T. Billiar,et al.  IV. Determinants of nitric oxide protection and toxicity in liver. , 1999, American journal of physiology. Gastrointestinal and liver physiology.

[90]  V. Briner,et al.  Nitric oxide stimulates chronic ceramide formation in glomerular endothelial cells. , 1999, Biochemical and biophysical research communications.

[91]  M. Zeng,et al.  Fas-induced caspase denitrosylation. , 1999, Science.

[92]  T. Uchiyama,et al.  Ceramide Generation in Nitric Oxide-induced Apoptosis , 1999, The Journal of Biological Chemistry.

[93]  B. Brüne,et al.  Nitric Oxide-induced S-Glutathionylation and Inactivation of Glyceraldehyde-3-phosphate Dehydrogenase* , 1999, The Journal of Biological Chemistry.

[94]  S. Snyder,et al.  Poly (ADP-ribose) polymerase, nitric oxide and cell death. , 1999, Trends in pharmacological sciences.

[95]  W. Dröge,et al.  Nitric-oxide-induced apoptosis in human leukemic lines requires mitochondrial lipid degradation and cytochrome C release. , 1999, Blood.

[96]  R. Radi,et al.  Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death. , 1999, Journal of immunology.

[97]  R. Park,et al.  Overexpression of protein kinase C isoforms protects RAW 264.7 macrophages from nitric oxide-induced apoptosis: involvement of c-Jun N-terminal kinase/stress-activated protein kinase, p38 kinase, and CPP-32 protease pathways. , 1999, Journal of immunology.

[98]  A. Zeiher,et al.  Nitric Oxide Inhibits Caspase-3 by S-Nitrosationin Vivo * , 1999, The Journal of Biological Chemistry.

[99]  J. Pfeilschifter,et al.  Nitric Oxide Donors Induce Stress Signaling via Ceramide Formation in Rat Renal Mesangial Cells* , 1999, The Journal of Biological Chemistry.

[100]  C. Suschek,et al.  Nitric Oxide Fully Protects against UVA-induced Apoptosis in Tight Correlation with Bcl-2 Up-regulation* , 1999, The Journal of Biological Chemistry.

[101]  B. Brüne,et al.  Overexpression of CuZn superoxide dismutase protects RAW 264.7 macrophages against nitric oxide cytotoxicity. , 1999, The Biochemical journal.

[102]  F. Marumo,et al.  Nitric oxide induces apoptotic death of cardiomyocytes via a cyclic-GMP-dependent pathway. , 1999, Experimental Cell Research.

[103]  B. Brüne,et al.  Role of mitogen-activated protein kinases in S-nitrosoglutathione-induced macrophage apoptosis. , 1999, Biochemistry.

[104]  B. McManus,et al.  Attenuated acute cardiac rejection in NOS2 -/- recipients correlates with reduced apoptosis. , 1999, Circulation.

[105]  T. Gotoh,et al.  Arginase II Downregulates Nitric Oxide (NO) Production and Prevents NO-mediated Apoptosis in Murine Macrophage-derived RAW 264.7 Cells , 1999, The Journal of cell biology.

[106]  W. Earnshaw.  Apoptosis: A cellular poison cupboard , 1999, Nature.

[107]  Ruedi Aebersold,et al.  Molecular characterization of mitochondrial apoptosis-inducing factor , 1999, Nature.

[108]  W. Bursch,et al.  Elevation of inducible nitric oxide synthase activity in human endometrium during menstruation. , 1999, Biology of reproduction.

[109]  T. Yasuda,et al.  Resistance to nitric oxide-mediated apoptosis in HL-60 variant cells is associated with increased activities of Cu,Zn-superoxide dismutase and catalase. , 1999, Free radical biology & medicine.

[110]  K. Webster,et al.  Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x. , 1999, Circulation research.

[111]  F. Joly,et al.  Effects of nitric oxide on the eosinophil survival in vitro. A role for nitrosyl‐heme , 1999, FEBS letters.

[112]  T. Uehara,et al.  Caspase Activation Accompanying Cytochrome c Release from Mitochondria Is Possibly Involved in Nitric Oxide‐Induced Neuronal Apoptosis in SH‐SY5Y Cells , 1999, Journal of neurochemistry.

[113]  Y. Tsujimoto,et al.  Bcl-2 Prevents Caspase-independent Cell Death* , 1998, The Journal of Biological Chemistry.

[114]  Jesse D. Roberts,et al.  Adenovirus-mediated Gene Transfer of cGMP-dependent Protein Kinase Increases the Sensitivity of Cultured Vascular Smooth Muscle Cells to the Antiproliferative and Pro-apoptotic Effects of Nitric Oxide/cGMP* , 1998, The Journal of Biological Chemistry.

[115]  M. S. Williams,et al.  Nitric oxide synthase plays a signaling role in TCR-triggered apoptotic death. , 1998, Journal of immunology.

[116]  K. Utsumi,et al.  Macrophage‐derived nitric oxide induces apoptosis of rat hepatoma cells in vivo , 1998, Hepatology.

[117]  J. Joseph,et al.  Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells. , 1998, The American journal of physiology.

[118]  C. Harris,et al.  p53 and vascular endothelial growth factor regulate tumor growth of NOS2-expressing human carcinoma cells , 1998, Nature Medicine.

[119]  A. Slomiany,et al.  Induction of caspase‐3 and nitric oxide synthase‐2 during gastric mucosal inflammatory reaction to Helicobacter pylori lipopolysaccharide , 1998, Biochemistry and molecular biology international.

[120]  D. Seol,et al.  Nitric Oxide Suppression of Apoptosis Occurs in Association with an Inhibition of Bcl-2 Cleavage and Cytochrome cRelease* , 1998, The Journal of Biological Chemistry.

[121]  J. M. Kim,et al.  Apoptosis of human intestinal epithelial cells after bacterial invasion. , 1998, The Journal of clinical investigation.

[122]  C. Lowenstein,et al.  Impaired liver regeneration in inducible nitric oxide synthasedeficient mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[123]  D. Wink,et al.  Redox generation of nitric oxide to radiosensitize hypoxic cells. , 1998, International journal of radiation oncology, biology, physics.

[124]  Simon C Watkins,et al.  Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells. , 1998, American journal of physiology. Lung cellular and molecular physiology.

[125]  M. Tohyama,et al.  Growth factors prevent changes in Bcl-2 and Bax expression and neuronal apoptosis induced by nitric oxide , 1998, Cell Death and Differentiation.

[126]  D. Nakayama,et al.  Nitric oxide causes apoptosis in pulmonary vascular smooth muscle cells. , 1998, The Journal of surgical research.

[127]  M. Tohyama,et al.  Involvement of Bcl‐2 Family and Caspase‐3‐Like Protease in NO‐Mediated Neuronal Apoptosis , 1998 .

[128]  N. Webster,et al.  The effect of nitric oxide and peroxynitrite on apoptosis in human polymorphonuclear leukocytes. , 1998, Free radical biology & medicine.

[129]  M. Shichiri,et al.  Transfection of inducible nitric oxide synthase gene causes apoptosis in vascular smooth muscle cells. , 1998, Circulation.

[130]  L. Brundin,et al.  The role of nitric oxide in bacillus Calmette-Guérin mediated anti-tumour effects in human bladder cancer. , 1998, British Journal of Cancer.

[131]  D. Wink,et al.  Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. , 1998, Free radical biology & medicine.

[132]  Y. Lazebnik,et al.  Caspases: enemies within. , 1998, Science.

[133]  V. Dixit,et al.  Death receptors: signaling and modulation. , 1998, Science.

[134]  Xing-li Wang,et al.  Nitric oxide induces and inhibits apoptosis through different pathways , 1998, FEBS letters.

[135]  T. Billiar,et al.  Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis. , 1998, Surgery.

[136]  F. Sigaux,et al.  B-cell chronic lymphocytic leukemia cells express a functional inducible nitric oxide synthase displaying anti-apoptotic activity. , 1998, Blood.

[137]  M. Weller,et al.  Induction of Nitric Oxide Synthase and Nitric Oxide‐Mediated Apoptosis in Neuronal PC12 Cells After Stimulation with Tumor Necrosis FActor‐α/Lipopolysaccharide , 1998 .

[138]  T. Billiar,et al.  Inducible nitric oxide synthase in the liver: regulation and function. , 1998, Biochemistry. Biokhimiia.

[139]  S. Cuzzocrea,et al.  Peroxynitrite‐induced thymocyte apoptosis: the role of caspases and poly (ADP‐ribose) synthetase (PARS) activation , 1998, Immunology.

[140]  E. Lapetina,et al.  Glutathione levels determine apoptosis in macrophages. , 1998, Biochemical and biophysical research communications.

[141]  M. Peter,et al.  Caspase activation is required for nitric oxide-mediated, CD95(APO-1/Fas)-dependent and independent apoptosis in human neoplastic lymphoid cells. , 1998, Blood.

[142]  R. Zamora,et al.  The role of prostaglandin E2 and nitric oxide in cell death in J774 murine macrophages. , 1998, European journal of pharmacology.

[143]  J. Thompson,et al.  Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor , 1998, The Journal of Neuroscience.

[144]  L. Sciola,et al.  Protective effect of deferoxamine on sodium nitroprusside-induced apoptosis in PC12 cells , 1998, Neuroscience Letters.

[145]  A. Zeiher,et al.  Nitric oxide inhibits APO-1/Fas-mediated cell death. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[146]  E. Sato,et al.  Nitric oxide regulates energy metabolism and Bcl-2 expression in intestinal epithelial cells. , 1998, American journal of physiology. Gastrointestinal and liver physiology.

[147]  C. Giulivi,et al.  Production of Nitric Oxide by Mitochondria* , 1998, The Journal of Biological Chemistry.

[148]  F. Sun,et al.  Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease. , 1998, American journal of physiology. Cell physiology.

[149]  R. Terkeltaub,et al.  Chondrocyte-derived apoptotic bodies and calcification of articular cartilage. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[150]  R. Siegel,et al.  Membrane Oligomerization and Cleavage Activates the Caspase-8 (FLICE/MACHα1) Death Signal* , 1998, The Journal of Biological Chemistry.

[151]  H. Simon,et al.  Disruption of Fas Receptor Signaling by Nitric Oxide in Eosinophils , 1998, The Journal of experimental medicine.

[152]  J. Mcgregor,et al.  Nitric oxide exposure inhibits induction of lymphokine-activated killer cells by inducing precursor apoptosis. , 1998, Nitric oxide : biology and chemistry.

[153]  Brent R. Stockwell,et al.  An Induced Proximity Model for Caspase-8 Activation* , 1998, The Journal of Biological Chemistry.

[154]  J. B. Hutchins,et al.  Mitochondrial Manganese Superoxide Dismutase Prevents Neural Apoptosis and Reduces Ischemic Brain Injury: Suppression of Peroxynitrite Production, Lipid Peroxidation, and Mitochondrial Dysfunction , 1998, The Journal of Neuroscience.

[155]  R. Park,et al.  Cyclic adenosine monophosphate inhibits nitric oxide-induced apoptosis in human leukemic HL-60 cells. , 1998, Cellular immunology.

[156]  B. Brüne,et al.  U937 apoptotic cell death by nitric oxide: Bcl-2 downregulation and caspase activation. , 1998, Experimental cell research.

[157]  T. Billiar,et al.  Nitric Oxide Inhibits Apoptosis by Preventing Increases in Caspase-3-like Activity via Two Distinct Mechanisms* , 1997, The Journal of Biological Chemistry.

[158]  C. Richter,et al.  Nitric oxide synthase activity in mitochondria , 1997, FEBS letters.

[159]  J. Loscalzo,et al.  Reduced glutathione prevents nitric oxide-induced apoptosis in vascular smooth muscle cells. , 1997, Biochimica et biophysica acta.

[160]  E. Nishio,et al.  Nitric oxide donor-induced apoptosis in smooth muscle cells is modulated by protein kinase C and protein kinase A. , 1997, European journal of pharmacology.

[161]  T. Billiar,et al.  Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. , 1997, Biochemical and biophysical research communications.

[162]  S. Ralston,et al.  Cytokine‐Induced Nitric Oxide Inhibits Bone Resorption by Inducing Apoptosis of Osteoclast Progenitors and Suppressing Osteoclast Activity , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[163]  Simon C Watkins,et al.  Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia. , 1997, Nitric oxide : biology and chemistry.

[164]  C. Szabó,et al.  DNA damage induced by peroxynitrite: subsequent biological effects. , 1997, Nitric oxide : biology and chemistry.

[165]  A. von Knethen,et al.  Cyclooxygenase‐2: an essential regulator of NO‐mediated apoptosis , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[166]  R. Knight,et al.  S-nitrosylation regulates apoptosis , 1997, Nature.

[167]  Simon C Watkins,et al.  Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-alpha-induced apoptosis and toxicity in the liver. , 1997, Journal of medicinal chemistry.

[168]  Simon C Watkins,et al.  Nitric Oxide Protects Cultured Rat Hepatocytes from Tumor Necrosis Factor-α-induced Apoptosis by Inducing Heat Shock Protein 70 Expression* , 1997, The Journal of Biological Chemistry.

[169]  H. Fusamoto,et al.  Helicobacter pylori extract stimulates inflammatory nitric oxide production. , 1996, Cancer letters.

[170]  J S Beckman,et al.  Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. , 1996, The American journal of physiology.

[171]  B. Brüne,et al.  Nitric oxide-induced apoptosis: p53-dependent and p53-independent signalling pathways. , 1996, The Biochemical journal.

[172]  E. Fontham,et al.  Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. , 1996, Cancer research.

[173]  Xiaodong Wang,et al.  Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c , 1996, Cell.

[174]  Jen-kun Lin,et al.  Induction of p53 and p21/WAF1/CIP1 expression by nitric oxide and their association with apoptosis in human cancer cells , 1996, Molecular carcinogenesis.

[175]  C. Harris,et al.  Nitric oxide-induced p53 accumulation and regulation of inducible nitric oxide synthase expression by wild-type p53. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[176]  M. A. Moro,et al.  Nitric oxide and peroxynitrite exert distinct effects on mitochondrial respiration which are differentially blocked by glutathione or glucose. , 1996, The Biochemical journal.

[177]  J. Stamler,et al.  Posttranslational Modification of Glyceraldehyde-3-phosphate Dehydrogenase by S-Nitrosylation and Subsequent NADH Attachment (*) , 1996, The Journal of Biological Chemistry.

[178]  M. Murphy,et al.  Peroxynitrite formed by simultaneous nitric oxide and superoxide generation causes cyclosporin-A-sensitive mitochondrial calcium efflux and depolarisation. , 1995, European journal of biochemistry.

[179]  M. Peter,et al.  Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor. , 1995, The EMBO journal.

[180]  S. Korsmeyer.  BCL-2 gene family and the regulation of programmed cell death. , 1995, Cancer research.

[181]  I. Lizasoain,et al.  The formation of nitric oxide donors from peroxynitrite , 1995, British journal of pharmacology.

[182]  M. Kubo,et al.  Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production. , 1995, Endocrinology.

[183]  J. Hotchkiss,et al.  Potential genotoxicity of chronically elevated nitric oxide: a review. , 1995, Mutation research.

[184]  Arul M. Chinnaiyan,et al.  FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis , 1995, Cell.

[185]  D. Goeddel,et al.  The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation , 1995, Cell.

[186]  I. Fidler,et al.  Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells , 1995, The Journal of experimental medicine.

[187]  C. Martínez-A,et al.  Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels. , 1995, The Journal of clinical investigation.

[188]  L. Dubertret,et al.  The nitric oxide donors, azide and hydroxylamine, inhibit the programmed cell death of cytokine‐deprived human eosinophils , 1995, FEBS letters.

[189]  C. Thompson,et al.  Apoptosis in the pathogenesis and treatment of disease , 1995, Science.

[190]  H. Steller.  Mechanisms and genes of cellular suicide , 1995, Science.

[191]  J. Stamler,et al.  Nitric oxide produced by human B lymphocytes inhibits apoptosis and Epstein-Barr virus reactivation , 1994, Cell.

[192]  B. Brüne,et al.  p53 expression in nitric oxide‐induced apoptosis , 1994, FEBS letters.

[193]  D. Wink,et al.  The Fpg protein, a DNA repair enzyme, is inhibited by the biomediator nitric oxide in vitro and in vivo. , 1994, Carcinogenesis.

[194]  R. Farias-Eisner,et al.  Nitric oxide is an important mediator for tumoricidal activity in vivo. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[195]  Carl Nathan,et al.  Nitric oxide synthases: Roles, tolls, and controls , 1994, Cell.

[196]  J. Stamler,et al.  Redox signaling: Nitrosylation and related target interactions of nitric oxide , 1994, Cell.

[197]  M. Nakane,et al.  Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. , 1994, Hypertension.

[198]  H. Bartsch,et al.  Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. , 1994, Mutation research.

[199]  S. Moncada,et al.  The L-arginine-nitric oxide pathway. , 1993, The New England journal of medicine.

[200]  M. Currie,et al.  Nitric oxide activates cyclooxygenase enzymes. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[201]  J. Hevel,et al.  Purification of the inducible murine macrophage nitric oxide synthase. Identification as a flavoprotein. , 1991, The Journal of biological chemistry.

[202]  F. Murad,et al.  Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[203]  C. Nathan,et al.  Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide , 1991, The Journal of experimental medicine.

[204]  T. Sugimura,et al.  L-arginine-dependent formation of N-nitrosamines by the cytosol of macrophages activated with lipopolysaccharide and interferon-gamma. , 1991, Carcinogenesis.

[205]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[206]  I. Fidler,et al.  Role of nitric oxide in lysis of tumor cells by cytokine-activated endothelial cells. , 1991, Cancer research.

[207]  B. Mayer,et al.  Purification of a Ca2+/calmodulin‐dependent nitric oxide synthase from porcine cerebellum , 1990, FEBS letters.

[208]  J. Tenu,et al.  Alterations of ribonucleotide reductase activity following induction of the nitrite-generating pathway in adenocarcinoma cells. , 1990, The Journal of biological chemistry.

[209]  G. Holländer,et al.  Nitric oxide production and Fas surface expression mediate two independent pathways of cytokine-induced murine beta-cell damage. , 2000, Diabetes.

[210]  H. Bernstein,et al.  Role of nitric oxide and peroxynitrite in bile salt-induced apoptosis: relevance to colon carcinogenesis. , 1999, Nutrition and cancer.

[211]  C. Harris,et al.  Cancer-prone oxyradical overload disease. , 1999, IARC scientific publications.

[212]  J. Liao,et al.  Arginase modulates nitric oxide production in activated macrophages. , 1998, American journal of physiology. Heart and circulatory physiology.

[213]  H. Drummond,et al.  Inhibition of 20-HETE production contributes to the vascular responses to nitric oxide. , 1997, Hypertension.

[214]  D. Wink,et al.  Nitric oxide enhancement of melphalan-induced cytotoxicity. , 1997, British Journal of Cancer.

[215]  D. Wink,et al.  A discussion of mechanisms of NO genotoxicity: implication of inhibition of DNA repair proteins. , 1997, Reviews of physiology, biochemistry and pharmacology.

[216]  James B. Mitchell,et al.  Chemical biology of nitric oxide: regulation and protective and toxic mechanisms. , 1996, Current topics in cellular regulation.

[217]  L. Ignarro,et al.  Negative modulation of nitric oxide synthase by nitric oxide and nitroso compounds. , 1995, Advances in pharmacology.

[218]  J. Beckman,et al.  The role of peroxynitrite in nitric oxide-mediated toxicity. , 1995, Current topics in microbiology and immunology.

[219]  F. Murad,et al.  Regulation of cytosolic guanylyl cyclase by nitric oxide: the NO-cyclic GMP signal transduction system. , 1994, Advances in pharmacology.

[220]  D. Wink,et al.  Inhibition of cytochromes P450 by nitric oxide and a nitric oxide-releasing agent. , 1993, Archives of biochemistry and biophysics.

[221]  C. Nathan,et al.  Role of nitric oxide synthesis in macrophage antimicrobial activity. , 1991, Current opinion in immunology.

[222]  L. Ignarro.  Biosynthesis and metabolism of endothelium-derived nitric oxide. , 1990, Annual review of pharmacology and toxicology.