Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging
暂无分享,去创建一个
E. Brunette | D. Stanimirovic | D. Callaghan | H. Xiong | Wandong Zhang | K. Pei | Hong Liu | D. Fatehi | Aimee Jones
[1] E. Brunette,et al. Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging , 2013, Fluids and Barriers of the CNS.
[2] Peilin Huang,et al. Abcg2 deficiency augments oxidative stress and cognitive deficits in Tg‐SwDI transgenic mice , 2012, Journal of neurochemistry.
[3] Nathan T. Ross,et al. A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease. , 2012, The Journal of clinical investigation.
[4] Stefan Platzer,et al. Small-Animal PET Imaging of Amyloid-Beta Plaques with [11C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease , 2012, PloS one.
[5] L. Walker,et al. The role of the ATP-binding cassette transporter P-glycoprotein in the transport of β-amyloid across the blood-brain barrier. , 2011, Current pharmaceutical design.
[6] H. Kroemer,et al. Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice , 2011, International journal of Alzheimer's disease.
[7] Xin Liu,et al. Site-specific enzymatic polysialylation of therapeutic proteins using bacterial enzymes , 2011, Proceedings of the National Academy of Sciences.
[8] B. Zlokovic,et al. Neurodegeneration and the neurovascular unit , 2010, Nature Medicine.
[9] R. Deane,et al. Low‐density lipoprotein receptor‐related protein‐1: a serial clearance homeostatic mechanism controlling Alzheimer’s amyloid β‐peptide elimination from the brain , 2010, Journal of neurochemistry.
[10] T. Veres,et al. Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodies , 2010, British Journal of Cancer.
[11] H. Kroemer,et al. MDR1–P‐glycoprotein (ABCB1)‐Mediated Disposition of Amyloid‐β Peptides: Implications for the Pathogenesis and Therapy of Alzheimer's Disease , 2010, Clinical pharmacology and therapeutics.
[12] Peilin Huang,et al. ABCG2 reduces ROS‐mediated toxicity and inflammation: a potential role in Alzheimer’s disease , 2010, Journal of neurochemistry.
[13] Sagar Agarwal,et al. Distribution of Gefitinib to the Brain Is Limited by P-glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2)-Mediated Active Efflux , 2010, Journal of Pharmacology and Experimental Therapeutics.
[14] David S. Miller,et al. Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-β in a Mouse Model of Alzheimer's Disease , 2010, Molecular Pharmacology.
[15] L. Lue,et al. ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood–Brain Barrier for Aβ1–40 Peptides , 2009, The Journal of Neuroscience.
[16] I. Romero,et al. P-Glycoprotein and Breast Cancer Resistance Protein Restrict Apical-to-Basolateral Permeability of Human Brain Endothelium to Amyloid-β , 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[17] L. Lue,et al. Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway , 2009, Neurobiology of Disease.
[18] R. Deane,et al. Clearance of amyloid-β peptide across the blood-brain barrier: Implication for therapies in Alzheimer’s disease , 2009 .
[19] E. Brunette,et al. Dynamic Analysis of the Blood-Brain Barrier Disruption in Experimental Stroke Using Time Domain in Vivo Fluorescence Imaging , 2008, Molecular imaging.
[20] Matthew P. Frosch,et al. Detection of isolated cerebrovascular β‐amyloid with pittsburgh compound B , 2008, Annals of neurology.
[21] John Woulfe,et al. Cholesterol retention in Alzheimer's brain is responsible for high β- and γ-secretase activities and Aβ production , 2008, Neurobiology of Disease.
[22] H. Kroemer,et al. MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier , 2007, Brain pathology.
[23] Elizabeth M C Hillman,et al. Optical brain imaging in vivo: techniques and applications from animal to man. , 2007, Journal of biomedical optics.
[24] A. Fagan,et al. P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model. , 2005, The Journal of clinical investigation.
[25] D. Stanimirovic,et al. The Transport Systems of the Blood–Brain Barrier , 2005 .
[26] A. Prat,et al. The Blood-Brain Barrier and Its Microenvironment : Basic Physiology to Neurological Disease , 2005 .
[27] S. Cole,et al. Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense. , 2005, Toxicology and applied pharmacology.
[28] Berislav V. Zlokovic,et al. Neurovascular mechanisms of Alzheimer's neurodegeneration , 2005, Trends in Neurosciences.
[29] H. Kroemer,et al. The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease. , 2004, Current Alzheimer research.
[30] D. Selkoe,et al. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics. , 2003, Annual review of pharmacology and toxicology.
[31] Hong Zhang,et al. The FASEB Journal express article 10.1096/fj.02-1131fje. Published online September 4, 2003. Expression and functional characterization of ABCG2 in brain endothelial cells and vessels , 2022 .
[32] Ann Marie Schmidt,et al. RAGE mediates amyloid-β peptide transport across the blood-brain barrier and accumulation in brain , 2003, Nature Medicine.
[33] Christiane Kunert-Keil,et al. Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans. , 2002, Pharmacogenetics.
[34] K. Fischbeck,et al. Toxic Proteins in Neurodegenerative Disease , 2002, Science.
[35] T. Wisniewski,et al. Circulating amyloid-beta peptide crosses the blood-brain barrier in aged monkeys and contributes to Alzheimer's disease lesions. , 2002, Vascular pharmacology.
[36] J. Bading,et al. Brain Clearance of Alzheimer's Amyloid-β40 in the Squirrel Monkey: A SPECT Study in a Primate Model of Cerebral Amyloid Angiopathy , 2002, Journal of drug targeting.
[37] Peter B. Reiner,et al. β‐Amyloid efflux mediated by p‐glycoprotein , 2001 .
[38] D. Holtzman,et al. Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. , 2000, The Journal of clinical investigation.
[39] J. Bading,et al. Cerebrovascular Accumulation and Increased Blood‐Brain Barrier Permeability to Circulating Alzheimer's Amyloid β Peptide in Aged Squirrel Monkey with Cerebral Amyloid Angiopathy , 1998, Journal of neurochemistry.
[40] C. Patlak,et al. Fate of Cerebrospinal Fluid‐Borne Amyloid β‐Peptide: Rapid Clearance into Blood and Appreciable Accumulation by Cerebral Arteries , 1996, Journal of neurochemistry.
[41] B. Zlokovic,et al. Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid β in guinea pigs , 1996, Neuroscience Letters.
[42] L. Rakić,et al. Transport of Leucine‐Enkephalin Across the Blood‐Brain Barrier in the Perfused Guinea Pig Brain , 1987, Journal of neurochemistry.
[43] D. Begley,et al. Blood-brain barrier permeability to leucine-enkephalin,d-Alanine2-d-leucine5-enkephalin and their N-terminal amino acid (tyrosine) , 1985, Brain Research.
[44] F. Calon,et al. ABCG2- and ABCG4-mediated efflux of amyloid-β peptide 1-40 at the mouse blood-brain barrier. , 2012, Journal of Alzheimer's disease : JAD.
[45] M. Leissring,et al. Characterization of insulin degrading enzyme and other amyloid-β degrading proteases in human serum: a role in Alzheimer's disease? , 2012, Journal of Alzheimer's disease : JAD.
[46] E. Brunette,et al. In vivo optical imaging of ischemic blood-brain barrier disruption. , 2011, Methods in molecular biology.
[47] G. Farrington,et al. In vitro and in vivo methods for assessing FcRn-mediated reverse transcytosis across the blood-brain barrier. , 2011, Methods in molecular biology.
[48] A. Abulrob,et al. Integrated platform for brain imaging and drug delivery across the blood-brain barrier. , 2011, Methods in molecular biology.
[49] D. Berg,et al. Neprilysin activity in cerebrospinal fluid is associated with dementia and amyloid-β42 levels in Lewy body disease. , 2010, Journal of Alzheimer's disease : JAD.
[50] Wandong Zhang,et al. ABC Transporters and Drug Efflux at the Blood-Brain Barrier , 2010, Reviews in the neurosciences.
[51] H. D. Vries. fluids and barriers of the CNS , 2010 .
[52] D. Evanko. Optical imaging of the native brain , 2009, Nature Methods.
[53] S. M. Robinson,et al. Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition. , 2009, Journal of Alzheimer's disease : JAD.
[54] H. Schägger. Tricine–SDS-PAGE , 2006, Nature Protocols.
[55] P. Reiner,et al. beta-Amyloid efflux mediated by p-glycoprotein. , 2001, Journal of neurochemistry.
[56] B. Zlokovic,et al. Blood-brain barrier uptake of the 40 and 42 amino acid sequences of circulating Alzheimer's amyloid beta in guinea pigs. , 1996, Neuroscience letters.