Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound.

[1]  A. Avdeef.  Solubility of sparingly-soluble ionizable drugs. , 2007, Advanced drug delivery reviews.

[2]  F. Martínez,et al.  Solubility of naproxen in several organic solvents at different temperatures , 2007 .

[3]  J. Comer,et al.  Equilibrium versus kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution--a validation study. , 2006, Journal of pharmaceutical sciences.

[4]  Gerd Folkers,et al.  Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies , 2006 .

[5]  K. Kawakami,et al.  Impact of the Amount of Excess Solids on Apparent Solubility , 2005, Pharmaceutical Research.

[6]  K. Box,et al.  Chasing equilibrium: measuring the intrinsic solubility of weak acids and bases. , 2005, Analytical chemistry.

[7]  Christel A. S. Bergström,et al.  Accuracy of calculated pH-dependent aqueous drug solubility. , 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[8]  Alex Avdeef,et al.  Absorption and Drug Development: Solubility, Permeability, and Charge State , 2003 .

[9]  A. Avdeef,et al.  pH-metric solubility. 3. Dissolution titration template method for solubility determination. , 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[10]  W. Streng.  Characterization of Compounds in Solution: Theory and Practice , 2001 .

[11]  L. Takahashi,et al.  Comparison of chromatographic and spectroscopic methods used to rank compounds for aqueous solubility. , 2001, Journal of pharmaceutical sciences.

[12]  P Ruelle,et al.  The hydrophobic effect. 2. Relative importance of the hydrophobic effect on the solubility of hydrophobes and pharmaceuticals in H-bonded solvents. , 1998, Journal of pharmaceutical sciences.

[13]  S. Yalkowsky,et al.  AQUAFAC 5 : AQUeous Functional group Activity Coefficients; application to alcohols and acids , 1997 .

[14]  Pravin Chaturvedi,et al.  Design principles for orally bioavailable drugs , 1996 .

[15]  G. Fazio,et al.  Solubility and solubilization properties of non-steroidal anti-inflammatory drugs , 1995 .

[16]  David E. Bugay,et al.  Physical Characterization of Pharmaceutical Solids , 1995, Pharmaceutical Research.

[17]  P. Taylor.  Ostwald ripening in emulsions , 1995 .

[18]  S. Yalkowsky,et al.  Correlation of Octanol/Water Solubility Ratios and Partition Coefficients , 1995 .

[19]  F. Etzweiler,et al.  Method for Measuring Aqueous Solubilities of Organic Compounds , 1995 .

[20]  T. Higuchi,et al.  Solubility determination of barely aqueous-soluble organic solids. , 1979, Journal of pharmaceutical sciences.

[21]  D. E. Cadwallader,et al.  Solubility of cholesterol and hormone drugs in water. , 1973, Journal of pharmaceutical sciences.

[22]  M. Rowland,et al.  Dissociation constants of sparingly soluble substances: nonlogarithmic linear titration curves. , 1971, Journal of pharmaceutical sciences.

[23]  Alex Avdeef,et al.  pH-Metric Solubility. 2: Correlation Between the Acid-Base Titration and the Saturation Shake-Flask Solubility-pH Methods , 2004, Pharmaceutical Research.

[24]  Alex Avdeef,et al.  Absorption and drug development , 2003 .

[25]  S. Yalkowsky,et al.  Aqueous solubility : methods of estimation for organic compounds , 1992 .

[26]  David J.W. Grant,et al.  Solubility behavior of organic compounds , 1990 .

[27]  John C. Dearden,et al.  The Measurement of Partition Coefficients , 1988 .

[28]  S. Bolton.  Pharmaceutical statistics: Practical and clinical applications , 1984 .

[29]  K. Florey,et al.  Analytical profiles of drug substances , 1972 .