Differential expression of facilitative glucose transporters in normal and tumour kidney tissues

To investigate the differences in the pattern of glucose transporter (GLUT) gene expression between normal and tumour tissues and among histological subtypes of renal cell carcinomas (RCCs), as malignant cells are characterized by increased glucose uptake and use.

[1]  D. Wilson.  Tissue , 2009, The Lancet.

[2]  M. Carrasco,et al.  Differential subcellular distribution of glucose transporters GLUT1–6 and GLUT9 in human cancer: Ultrastructural localization of GLUT1 and GLUT5 in breast tumor tissues , 2006, Journal of cellular physiology.

[3]  H. Kajiyama,et al.  Placental leucine aminopeptidase (P-LAP) and glucose transporter 4 (GLUT4) expression in benign, borderline, and malignant ovarian epithelia. , 2005, Gynecologic oncology.

[4]  D. Bowden,et al.  Differential expression of glucose transporters in normal and pathologic thyroid tissue. , 2004, Thyroid : official journal of the American Thyroid Association.

[5]  C. Cheeseman,et al.  Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestine. , 2004, American journal of physiology. Gastrointestinal and liver physiology.

[6]  H. Moch,et al.  Chemokine receptor CXCR4 downregulated by von Hippel–Lindau tumour suppressor pVHL , 2003, Nature.

[7]  S. Petrou,et al.  Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes. , 2003, Biochemical and biophysical research communications.

[8]  J. Best,et al.  Differential expression of GLUT12 in breast cancer and normal breast tissue. , 2003, Cancer letters.

[9]  E. Williams,et al.  Expression and localization of GLUT1 and GLUT12 in prostate carcinoma , 2003, Cancer.

[10]  H. Stettner,et al.  Fluorine-18-fluorodeoxyglucose positron emission tomography in the preoperative assessment of thyroid nodules in an endemic goiter area. , 2003, Surgery.

[11]  H. Freeze,et al.  GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms. , 2002, Genomics.

[12]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[13]  P. Dawson,et al.  Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1. , 2001, Molecular genetics and metabolism.

[14]  H. Gröne,et al.  Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas. , 2001, Cancer research.

[15]  A. Saltiel.  New Perspectives into the Molecular Pathogenesis and Treatment of Type 2 Diabetes , 2001, Cell.

[16]  T. Yoshikawa,et al.  Expression of facilitative glucose transporters in gastric tumors. , 1999, Hepato-gastroenterology.

[17]  L. Huang,et al.  Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway , 1998 .

[18]  S. Satoh,et al.  Expression of facilitative glucose transporter isoforms in lung carcinomas: its relation to histologic type, differentiation grade, and tumor stage. , 1998, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

[19]  A. Harris,et al.  Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[20]  M. Younes,et al.  Immunohistochemical detection of glut 3 in human tumors and normal tissues , 1997 .

[21]  M. Younes,et al.  Immunohistochemical detection of Glut3 in human tumors and normal tissues. , 1997, Anticancer research.

[22]  J. Baselga,et al.  Expression of the fructose transporter GLUT5 in human breast cancer. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[23]  B. Ebert,et al.  Hypoxia and Mitochondrial Inhibitors Regulate Expression of Glucose Transporter-1 via Distinct Cis-acting Sequences (*) , 1995, The Journal of Biological Chemistry.

[24]  B. Ebert,et al.  Hypoxic Regulation of Lactate Dehydrogenase A , 1995, The Journal of Biological Chemistry.

[25]  K. Takata,et al.  Investigative Urology: Immunohistochemical Localization of Glucose Transporters in Human Renal Cell Carcinoma , 1995 .

[26]  K. Takata,et al.  Immunohistochemical localization of glucose transporters in human renal cell carcinoma. , 1995, The Journal of urology.

[27]  H. Minn,et al.  Expression of glucose transporters in head‐and‐neck tumors , 1994, International journal of cancer.

[28]  R L Wahl,et al.  An Immunohistochemical Study , 2006 .

[29]  R. Plevin,et al.  Growth factors, mitogens, oncogenes and the regulation of glucose transport. , 1993, Cellular signalling.

[30]  G I Bell,et al.  Structure and function of mammalian facilitative sugar transporters. , 1993, The Journal of biological chemistry.

[31]  T. Jess,et al.  Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors. , 1993, The Biochemical journal.

[32]  C. Burant,et al.  Fructose transporter in human spermatozoa and small intestine is GLUT5. , 1992, The Journal of biological chemistry.

[33]  N. Tallada,et al.  An Immunohistochemical Study , 1992 .

[34]  Kazutomo Inoue,et al.  Over-expression of facilitative glucose transporter genes in human cancer. , 1990, Biochemical and biophysical research communications.

[35]  M Hatanaka,et al.  Transport of sugars in tumor cell membranes. , 1974, Biochimica et biophysica acta.

[36]  K. Isselbacher.  Sugar and amino acid transport by cells in culture--differences between normal and malignant cells. , 1972, The New England journal of medicine.

[37]  K. Isselbacher.  A medical treatment for gallstones? , 1972, The New England journal of medicine.

[38]  O. Warburg.  [Origin of cancer cells]. , 1956, Oncologia.