Sensor for headspace pressure and H2O concentration measurements in closed vials by tunable diode laser absorption spectroscopy

[1]  Mackenzie Ap.  APPARATUS FOR MICROSCOPIC OBSERVATIONS DURING FREEZE-DRYING (AFBR FREEZE-DRYING MICROSCOPE MODEL 2). , 1964 .

[2]  Ellis E. Whiting,et al.  An empirical approximation to the Voigt profile , 1968 .

[3]  S. R. Drayson.  Rapid computation of the Voigt profile , 1976 .

[4]  D. Rutledge,et al.  Monitoring Freeze‐Drying by Low Resolution Pulse NMR: Determination of Sublimation Endpoint , 1991 .

[5]  S L Nail,et al.  Methodology for in-process determination of residual water in freeze-dried products. , 1992, Developments in biological standardization.

[6]  S. Johnson,et al.  Measurement of Water Vapor Pressure and Activity Using Infrared Diode Laser Absorption Spectroscopy , 1993 .

[7]  J P Connelly,et al.  Monitor lyophilization with mass spectrometer gas analysis. , 1993, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

[8]  J Biguet,et al.  Moisture measurement: a new method for monitoring freeze-drying cycles. , 1993, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

[9]  R. de Ruiter,et al.  Lyophilization of biotechnology products. , 1994, PDA journal of pharmaceutical science and technology.

[10]  G. Corrieu,et al.  A method for on-line determination of residual water content and sublimation end-point during freeze-drying , 1996 .

[11]  M. Pikal,et al.  Intravial distribution of moisture during the secondary drying stage of freeze drying. , 1997, PDA journal of pharmaceutical science and technology.

[12]  P. Cameron.  Good Pharmaceutical Freeze-Drying Practice , 1997 .

[13]  S L Nail,et al.  Evaluation of manometric temperature measurement as a method of monitoring product temperature during lyophilization. , 1997, PDA journal of pharmaceutical science and technology.

[14]  M. Allen,et al.  Diode laser absorption sensors for gas-dynamic and combustion flows. , 1998, Measurement science & technology.

[15]  R. Suryanarayanan,et al.  Characterization of phase transitions during freeze-drying by in situ X-ray powder diffractometry. , 1998, Pharmaceutical development and technology.

[16]  C. Corsi,et al.  High-resolution measurements of line intensity, broadening and shift of CO around m , 1999 .

[17]  Hal Westberg,et al.  Measurement of atmospheric ammonia at a dairy using differential optical absorption spectroscopy in the mid-ultraviolet , 2002 .

[18]  R. Mahajan,et al.  Rapid headspace oxygen analysis for pharmaceutical packaging applications , 2002 .

[19]  Chung C. Hsu,et al.  Application of frequency-modulated spectroscopy in vacuum seal integrity testing of lyophilized biological products. , 2004, PDA journal of pharmaceutical science and technology.

[20]  J. Carpenter,et al.  Real-Time in Situ Monitoring of Lysozyme During Lyophilization Using Infrared Spectroscopy: Dehydration Stress in the Presence of Sucrose , 1997, Pharmaceutical Research.

[21]  Gang Li,et al.  The HITRAN 2008 molecular spectroscopic database , 2005 .

[22]  Sune Svanberg,et al.  Diode laser absorption spectroscopy for studies of gas exchange in fruits , 2006 .

[23]  Steven J Davis,et al.  Evaluation of tunable diode laser absorption spectroscopy for in-process water vapor mass flux measurements during freeze drying. , 2007, Journal of pharmaceutical sciences.

[24]  T.P. Jenkins,et al.  Diode laser absorption sensor for detecting oxygen in head space of vials , 2008, 2008 IEEE Sensors.

[25]  Steven L Nail,et al.  Rapid determination of vial heat transfer parameters using tunable diode laser absorption spectroscopy (TDLAS) in response to step-changes in pressure set-point during freeze-drying. , 2009, Journal of pharmaceutical sciences.

[26]  Michael J Pikal,et al.  Non-invasive product temperature determination during primary drying using tunable diode laser absorption spectroscopy. , 2009, Journal of pharmaceutical sciences.

[27]  K. Ward,et al.  Headspace Moisture Mapping and the Information That Can Be Gained about Freeze-Dried Materials and Processes , 2011, PDA Journal of Pharmaceutical Science and Technology.

[28]  W. Kessler,et al.  Optimization of the Secondary Drying Step in Freeze Drying Using TDLAS Technology , 2011, AAPS PharmSciTech.

[29]  Mehmet S. Kizil,et al.  A review of developments in near infrared methane detection based on tunable diode laser , 2012 .

[30]  Lin Ma,et al.  A laser extinction based sensor for simultaneous droplet size and vapor measurement , 2012 .

[31]  D. Banji,et al.  FREQUENCY MODULATION SPECTROSCOPY- A REVIEW , 2012 .

[32]  Sune Svanberg,et al.  Non-intrusive headspace gas measurements by laser spectroscopy – Performance validation by a reference sensor , 2012 .