Enhancement of optoacoustic tissue contrast with absorbing nanoparticles

Laser induced phase transition in the water surrounding absorbing nanoparticle results in dramatic enhancement of the thermoacoustic efficiency and excitation of high- amplitude pressure waves. Feasibility study was performed in tissue phantoms. Experiments supported with theoretical model demonstrated possibility to increase the efficiency of optoacoustic generation in tissue up to two orders of magnitude by application of absorbing carbon and gold nanoparticles.

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