Nonadherence with Immunosuppressive Drugs: Us Compared with European Kidney Transplant Recipients

tion negatively affects clinical and economical outcomes in kidney transplantation and therefore has come under increased scrutiny. A recent comprehensive review from our group on nonadherence in kidney transplantation reports that the prevalence of nonadherence with immunosuppressive drugs ranges from 2% to 67% depending on case-finding methods, measurement methods, and operational definitions. The weighted mean of nonadherence with immunosuppressive drugs over different publications is 27.7%. Nonadherence is an etiological factor in 16.3% of the graft losses and 19.9% of the late acute rejections in kidney transplant recipients. Studying underlying dynamics and factors linked to nonadherence with immunosuppressive drugs in Nonadherence with immunosuppressive drugs: US compared with European kidney transplant recipients

[1]  Matthias Cavassini,et al.  Correlates of Self-Reported Nonadherence to Antiretroviral Therapy in HIV-Infected Patients: The Swiss HIV Cohort Study , 2006, Journal of acquired immune deficiency syndromes.

[2]  F. Dobbels,et al.  Prevalence, consequences, and determinants of nonadherence in adult renal transplant patients: a literature review , 2005, Transplant international : official journal of the European Society for Organ Transplantation.

[3]  F. Dobbels,et al.  Adherence to the Therapeutic Regimen in Heart, Lung, and Heart‐Lung Transplant Recipients , 2005, The Journal of cardiovascular nursing.

[4]  L. Osterberg,et al.  Adherence to medication. , 2005, The New England journal of medicine.

[5]  A. L. Dal-Fabbro,et al.  Adherence to long term therapies: evidence for action , 2005 .

[6]  A. Israni,et al.  Race and electronically measured adherence to immunosuppressive medications after deceased donor renal transplantation. , 2005, Journal of the American Society of Nephrology : JASN.

[7]  F. Dobbels,et al.  Noncompliance with immunosuppressive regimen in organ transplantation: is it worth worrying about? , 2005, Acta gastro-enterologica Belgica.

[8]  J. Dipiro,et al.  Comparing renal transplant patients’ adherence to free cyclosporine and free tacrolimus immunosuppressant therapy , 2005, Clinical transplantation.

[9]  G Laufer,et al.  Predictors of Lung Transplant Survival in Eurotransplant , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[10]  J. Squifflet,et al.  Health-related quality of life and symptom experience in tacrolimus-based regimens after renal transplantation: a multicentre study , 2003, Transplant international : official journal of the European Society for Organ Transplantation.

[11]  H. V. van Houwelingen,et al.  Mortality rates after heart transplantation: How to compare center-specific outcome data? , 2003, Transplantation.

[12]  Thomas Bodenheimer,et al.  Improving primary care for patients with chronic illness: the chronic care model, Part 2. , 2002, JAMA.

[13]  Thomas Bodenheimer,et al.  Improving primary care for patients with chronic illness. , 2002, JAMA.

[14]  J. Harrell,et al.  Racial and Socioeconomic Differences in Risk Factors for Cardiovascular Disease Among Southern Rural Women , 2002, Nursing research.

[15]  S. Geest,et al.  Behavioral Strategies for Long‐Term Survival of Transplant Recipients , 2002 .

[16]  M. Skeans,et al.  The natural history of azathioprine compliance after renal transplantation. , 2001, Kidney international.

[17]  Patricia S. Jones,et al.  An Adaptation of Brislin’s Translation Model for Cross-cultural Research , 2001, Nursing research.

[18]  B Bunzel,et al.  Noncompliance in organ transplant recipients: a literature review. , 2000, General hospital psychiatry.

[19]  B Bunzel,et al.  Solid Organ Transplantation: Are there Predictors for Posttransplant Noncompliance? A Literature Overview , 2000, Transplantation.

[20]  S. Greenstein,et al.  Evaluation of a multivariate model predicting noncompliance with medication regimens among renal transplant patients. , 2000, Transplantation.

[21]  T. Michelon,et al.  Kidney graft failure due to noncompliance. , 1999, Transplantation proceedings.

[22]  R. de Marco,et al.  International variations in asthma treatment compliance: the results of the European Community Respiratory Health Survey (ECRHS). , 1999, The European respiratory journal.

[23]  B. Hylander,et al.  An international study of patient compliance with hemodialysis. , 1999, JAMA.

[24]  S. Greenstein,et al.  Compliance and noncompliance in patients with a functioning renal transplant: a multicenter study. , 1998, Transplantation.

[25]  J. Ehrich,et al.  Non-compliance following renal transplantation in children and adolescents , 1998, Pediatric Nephrology.

[26]  P. Moons,et al.  Late acute rejection and subclinical noncompliance with cyclosporine therapy in heart transplant recipients. , 1998, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[27]  S. Greenstein,et al.  Differences between compliers and partial compliers: a multicenter study. , 1998, Transplantation proceedings.

[28]  M. Henry,et al.  Medication compliance following renal transplantation. , 1998, Transplantation.

[29]  D. Gould,et al.  Non-adherence with medications in organ transplant patients: a literature review. , 1997, Journal of advanced nursing.

[30]  I. Abraham,et al.  Measuring Transplant Patients' Compliance with Immunosuppressive Therapy , 1996, Western journal of nursing research.

[31]  A. Hoitsma,et al.  MEDICATION COMPLIANCE AFTER RENAL TRANSPLANTATION , 1995, Transplantation.

[32]  S. Geest,et al.  INCIDENCE, DETERMINANTS, AND CONSEQUENCES OF SUBCLINICAL NONCOMPLIANCE WITH IMMUNOSUPPRESSIVE THERAPY IN RENAL TRANSPLANT RECIPIENTS , 1995, Transplantation.

[33]  I. Sketris,et al.  Factors affecting compliance with cyclosporine in adult renal transplant patients. , 1994, Transplantation proceedings.

[34]  N. Zuhdi,et al.  Medication noncompliance and its relationship to financial factors after heart transplantation. , 1994, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.

[35]  R. Pollak,et al.  A STUDY OF TREATMENT COMPLIANCE FOLLOWING KIDNEY TRANSPLANTATION , 1993, Transplantation.

[36]  E. Meydrech,et al.  Racial differences in the survival of cadaveric renal allografts. Overriding effects of HLA matching and socioeconomic factors. , 1992, The New England journal of medicine.

[37]  E. Santiago-delpin,et al.  Psychosocial profile of noncompliant transplant patients. , 1991, Transplantation proceedings.

[38]  C. V. van Buren,et al.  Causes of graft loss beyond two years in the cyclosporine era. , 1990, Transplantation.

[39]  L. Morales-Otero,et al.  Transplantation in Hispanics: the Puerto Rico experience. , 1989, Transplantation proceedings.

[40]  M. Rovelli,et al.  Noncompliance in renal transplant recipients: evaluation by socioeconomic groups. , 1989, Transplantation proceedings.

[41]  D. Hull,et al.  Noncompliance in Organ Transplant Recipients , 1989, Transplantation.

[42]  R. Didlake,et al.  Patient noncompliance: a major cause of late graft failure in cyclosporine-treated renal transplants. , 1988, Transplantation proceedings.

[43]  D. Cooper.  Orthotopic and heterotopic transplantation of the heart: the Cape Town experience. , 1984, Annals of the Royal College of Surgeons of England.

[44]  S. Geest,et al.  Supporting medication adherence in renal transplantation (SMART): a randomized controlled trial to improve adherence with the immunosuppressive regimen , 2005 .

[45]  H. Feldman,et al.  Haemodialysis prescription, adherence and nutritional indicators in five European countries: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). , 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[46]  S. Greenstein,et al.  Postrenal transplant compliance from the perspective of African-Americans, Hispanic-Americans, and Anglo-Americans. , 1997, Advances in renal replacement therapy.

[47]  N. Sumrani,et al.  Causes of late renal allograft failure in the ciclosporin era. , 1992, Nephron.