810 nm Wavelength light: An effective therapy for transected or contused rat spinal cord

Light therapy has biomodulatory effects on central and peripheral nervous tissue. Spinal cord injury (SCI) is a severe central nervous system trauma with no effective restorative therapies. The effectiveness of light therapy on SCI caused by different types of trauma was determined.

[1]  P. Lapchak,et al.  Transcranial Infrared Laser Therapy Improves Clinical Rating Scores After Embolic Strokes in Rabbits , 2004, Stroke.

[2]  Volker Dietz,et al.  Efficient testing of motor function in spinal cord injured rats , 2000, Brain Research.

[3]  A Curt,et al.  Validation of the weight-drop contusion model in rats: a comparative study of human spinal cord injury. , 2000, Journal of neurotrauma.

[4]  Thomas Benesch,et al.  Pain relief by single low-level laser irradiation in orthodontic patients undergoing fixed appliance therapy. , 2006, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics.

[5]  Bernd Fritzsch,et al.  Dextran amines in neuronal tracing , 1990, Trends in Neurosciences.

[6]  Alexander Sasha Rabchevsky,et al.  Rat models of traumatic spinal cord injury to assess motor recovery. , 2007, ILAR journal.

[7]  K. Fouad,et al.  Combining Schwann Cell Bridges and Olfactory-Ensheathing Glia Grafts with Chondroitinase Promotes Locomotor Recovery after Complete Transection of the Spinal Cord , 2005, The Journal of Neuroscience.

[8]  J. A. Gruner,et al.  A monitored contusion model of spinal cord injury in the rat. , 1992, Journal of neurotrauma.

[9]  L. Heimer,et al.  In vivo anterograde and retrograde axonal trnasport of the fluoresecent rhodamine-dextran-amine, Fluor-Ruby, within the CNS , 1990, Brain Research.

[10]  Semion Rochkind,et al.  Transplantation of embryonal spinal cord nerve cells cultured on biodegradable microcarriers followed by low power laser irradiation for the treatment of traumatic paraplegia in rats , 2002, Neurological research.

[11]  M. J. Moore,et al.  Animal models of spinal cord injury for evaluation of tissue engineering treatment strategies. , 2004, Biomaterials.

[12]  M. Tuszynski,et al.  Transient Growth Factor Delivery Sustains Regenerated Axons after Spinal Cord Injury , 2007, The Journal of Neuroscience.

[13]  Stefano Geuna,et al.  Phototherapy promotes regeneration and functional recovery of injured peripheral nerve , 2004, Neurological research.

[14]  Amir Oron,et al.  low-level laser therapy applied transcranially to mice following traumatic brain injury significantly reduces long-term neurological deficits. , 2007, Journal of neurotrauma.

[15]  A. Manira,et al.  Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[16]  G. Raisman,et al.  Functional Repair of the Corticospinal Tract by Delayed Transplantation of Olfactory Ensheathing Cells in Adult Rats , 2003, The Journal of Neuroscience.

[17]  Michael S. Beattie,et al.  Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection , 1996, Experimental Neurology.

[18]  Jieli Chen,et al.  Low-Level Laser Therapy Applied Transcranially to Rats After Induction of Stroke Significantly Reduces Long-Term Neurological Deficits , 2006, Stroke.

[19]  Stefano Geuna,et al.  Phototherapy for enhancing peripheral nerve repair: A review of the literature , 2005, Muscle & nerve.

[20]  R. Waynant,et al.  Photobiomodulation improves cutaneous wound healing in an animal model of type II diabetes. , 2004, Photomedicine and laser surgery.

[21]  Michael R Hamblin,et al.  Low‐level light stimulates excisional wound healing in mice , 2007, Lasers in surgery and medicine.

[22]  I. Biton,et al.  Development of a tissue-engineered composite implant for treating traumatic paraplegia in rats , 2006, European Spine Journal.

[23]  M. Schwab.  Repairing the Injured Spinal Cord , 2002, Science.

[24]  R. Waynant,et al.  Light promotes regeneration and functional recovery and alters the immune response after spinal cord injury , 2005, Lasers in surgery and medicine.

[25]  M. Bavbek,et al.  Antibodies neutralizing Nogo-A increase pan-cadherin expression and motor recovery following spinal cord injury in rats , 2007, Spinal Cord.

[26]  B. Stanfield.  The development of the corticospinal projection , 1992, Progress in Neurobiology.

[27]  M. Filbin,et al.  cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury , 2004, Nature Medicine.

[28]  D. Basso,et al.  A sensitive and reliable locomotor rating scale for open field testing in rats. , 1995, Journal of neurotrauma.

[29]  Hari Shanker Sharma,et al.  A Select Combination of Neurotrophins Enhances Neuroprotection and Functional Recovery following Spinal Cord Injury , 2007, Annals of the New York Academy of Sciences.

[30]  Wise Young,et al.  Spinal cord contusion models. , 2002, Progress in brain research.

[31]  V. Dietz,et al.  Locomotor Recovery in Spinal Cord-Injured Rats Treated with an Antibody Neutralizing the Myelin-Associated Neurite Growth Inhibitor Nogo-A , 2001, The Journal of Neuroscience.

[32]  D. Nance,et al.  Fluorescent dextrans as sensitive anterograde neuroanatomical tracers: Applications and pitfalls , 1990, Brain Research Bulletin.

[33]  J. Relton,et al.  Blockade of Nogo-66, Myelin-Associated Glycoprotein, and Oligodendrocyte Myelin Glycoprotein by Soluble Nogo-66 Receptor Promotes Axonal Sprouting and Recovery after Spinal Injury , 2004, The Journal of Neuroscience.

[34]  Amir Oron,et al.  Transcranial application of low‐energy laser irradiation improves neurological deficits in rats following acute stroke , 2006, Lasers in surgery and medicine.

[35]  J. Anders,et al.  Ensheathing Cells and Methylprednisolone Promote Axonal Regeneration and Functional Recovery in the Lesioned Adult Rat Spinal Cord , 2002, The Journal of Neuroscience.