Default mode network connectivity indicates episodic memory capacity in mesial temporal lobe epilepsy

The clinical relevance of resting state functional connectivity in neurologic disorders, including mesial temporal lobe epilepsy (mTLE), remains unclear. This study investigated how connectivity in the default mode network changes with unilateral damage to one of its nodes, the hippocampus (HC), and how such connectivity can be exploited clinically to characterize memory deficits and indicate postsurgical memory change.

[1]  Ashwini Sharan,et al.  Extratemporal functional connectivity impairments at rest are related to memory performance in mesial temporal epilepsy , 2013, Human brain mapping.

[2]  Cornelis J. Stam,et al.  Activity Dependent Degeneration Explains Hub Vulnerability in Alzheimer's Disease , 2012, PLoS Comput. Biol..

[3]  J. Gotman,et al.  Patterns of altered functional connectivity in mesial temporal lobe epilepsy , 2012, Epilepsia.

[4]  Katherine E. Prater,et al.  Functional connectivity tracks clinical deterioration in Alzheimer's disease , 2012, Neurobiology of Aging.

[5]  Roxanne Khamsi,et al.  Diagnosis by default , 2012, Nature Medicine.

[6]  H. Shang,et al.  A meta-analysis of voxel-based morphometry studies on unilateral refractory temporal lobe epilepsy , 2012, Epilepsy Research.

[7]  M. McAndrews,et al.  Neuropsychology in Temporal Lobe Epilepsy: Influences from Cognitive Neuroscience and Functional Neuroimaging , 2012, Epilepsy research and treatment.

[8]  Rodrigo M. Braga,et al.  Echoes of the Brain within the Posterior Cingulate Cortex , 2012, The Journal of Neuroscience.

[9]  Jean Gotman,et al.  Combining EEG and fMRI in the study of epileptic discharges , 2011, Epilepsia.

[10]  Huafu Chen,et al.  Default mode network abnormalities in mesial temporal lobe epilepsy: A study combining fMRI and DTI , 2011, Human brain mapping.

[11]  Lars T Westlye,et al.  Increased Hippocampal Default Mode Synchronization during Rest in Middle-Aged and Elderly APOE ε4 Carriers: Relationships with Memory Performance , 2011, The Journal of Neuroscience.

[12]  Samuel Wiebe,et al.  Neuropsychological outcomes after epilepsy surgery: Systematic review and pooled estimates , 2011, Epilepsia.

[13]  M. Corbetta,et al.  Episodic Memory Retrieval, Parietal Cortex, and the Default Mode Network: Functional and Topographic Analyses , 2011, The Journal of Neuroscience.

[14]  Jack J. Lin,et al.  The neurobiology of cognitive disorders in temporal lobe epilepsy , 2011, Nature Reviews Neurology.

[15]  C. Ranganath.  A unified framework for the functional organization of the medial temporal lobes and the phenomenology of episodic memory , 2010, Hippocampus.

[16]  R. Nathan Spreng,et al.  Patterns of Brain Activity Supporting Autobiographical Memory, Prospection, and Theory of Mind, and Their Relationship to the Default Mode Network , 2010, Journal of Cognitive Neuroscience.

[17]  Neda Bernasconi,et al.  Cortical thickness analysis in temporal lobe epilepsy , 2010, Neurology.

[18]  Huafu Chen,et al.  Altered spontaneous neuronal activity of the default-mode network in mesial temporal lobe epilepsy , 2010, Brain Research.

[19]  R. Buckner,et al.  Functional-Anatomic Fractionation of the Brain's Default Network , 2010, Neuron.

[20]  M. Symms,et al.  Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection , 2010, Brain : a journal of neurology.

[21]  M. Raichle,et al.  Disease and the brain's dark energy , 2010, Nature Reviews Neurology.

[22]  Associative reinstatement: A novel approach to assessing associative memory in patients with unilateral temporal lobe excisions , 2009, Neuropsychologia.

[23]  Karl K. Szpunar,et al.  Laboratory-based and autobiographical retrieval tasks differ substantially in their neural substrates , 2009, Neuropsychologia.

[24]  M. Cheung,et al.  Pre- and postoperative fMRI and clinical memory performance in temporal lobe epilepsy , 2009, Journal of Neurology, Neurosurgery & Psychiatry.

[25]  O. Sporns,et al.  Complex brain networks: graph theoretical analysis of structural and functional systems , 2009, Nature Reviews Neuroscience.

[26]  Keith A. Johnson,et al.  Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease , 2009, The Journal of Neuroscience.

[27]  O Sporns,et al.  Predicting human resting-state functional connectivity from structural connectivity , 2009, Proceedings of the National Academy of Sciences.

[28]  Peter Fransson,et al.  The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis , 2008, NeuroImage.

[29]  O. Sporns,et al.  Mapping the Structural Core of Human Cerebral Cortex , 2008, PLoS biology.

[30]  M. Sperling,et al.  When should a resection sparing mesial structures be considered for temporal lobe epilepsy? , 2008, Epilepsy & Behavior.

[31]  E. Halgren,et al.  Subcortical and cerebellar atrophy in mesial temporal lobe epilepsy revealed by automatic segmentation , 2008, Epilepsy Research.

[32]  D. Schacter,et al.  The Brain's Default Network , 2008, Annals of the New York Academy of Sciences.

[33]  J. Schramm,et al.  Differential effects of temporal pole resection with amygdalohippocampectomy versus selective amygdalohippocampectomy on material‐specific memory in patients with mesial temporal lobe epilepsy , 2008, Epilepsia.

[34]  Andreas Schulze-Bonhage,et al.  Hippocampal functional connectivity reflects verbal episodic memory network integrity , 2007, Neuroreport.

[35]  Morris Moscovitch,et al.  Consequences of hippocampal damage across the autobiographical memory network in left temporal lobe epilepsy. , 2007, Brain : a journal of neurology.

[36]  M. Fox,et al.  Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging , 2007, Nature Reviews Neuroscience.

[37]  John S Duncan,et al.  Reorganization of Verbal and Nonverbal Memory in Temporal Lobe Epilepsy Due to Unilateral Hippocampal Sclerosis , 2007, Epilepsia.

[38]  A. Kleinschmidt,et al.  Temporal lobe interictal epileptic discharges affect cerebral activity in “default mode” brain regions , 2006, Human brain mapping.

[39]  B. Levine,et al.  The functional neuroanatomy of autobiographical memory: A meta-analysis , 2006, Neuropsychologia.

[40]  Sallie Baxendale,et al.  Predicting Memory Decline Following Epilepsy Surgery: A Multivariate Approach , 2006, Epilepsia.

[41]  Lucie Hertz-Pannier,et al.  Late plasticity for language in a child's non-dominant hemisphere: a pre- and post-surgery fMRI study. , 2002, Brain : a journal of neurology.

[42]  A. Dale,et al.  Whole Brain Segmentation Automated Labeling of Neuroanatomical Structures in the Human Brain , 2002, Neuron.

[43]  M. Kurthen,et al.  Memory and epilepsy: characteristics, course, and influence of drugs and surgery , 2001, Current opinion in neurology.

[44]  C. Polkey,et al.  Recognition memory for words and faces following unilateral temporal lobectomy. , 1995, The British journal of clinical psychology.

[45]  G. Chelune.  Hippocampal adequacy versus functional reserve: predicting memory functions following temporal lobectomy. , 1995, Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists.

[46]  R. Rausch.  Anatomical substrates of interictal memory deficits in temporal lobe epileptics. , 1987, International journal of neurology.

[47]  W. Penfield,et al.  Memory deficit produced by bilateral lesions in the hippocampal zone. , 1958, A.M.A. archives of neurology and psychiatry.

[48]  B. Milner,et al.  Psychological defects produced by temporal lobe excision. , 1958, Research publications - Association for Research in Nervous and Mental Disease.