Sowing the seeds of cancer: telomeres and age-associated tumorigenesis
暂无分享,去创建一个
[1] J. Ferlay,et al. Global estimates of cancer prevalence for 27 sites in the adult population in 2008 , 2013, International journal of cancer.
[2] T. Davoli,et al. Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells. , 2012, Cancer cell.
[3] Kerstin Schneeberger,et al. Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer , 2012, EMBO molecular medicine.
[4] M. Hande,et al. Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions , 2012, The EMBO journal.
[5] F. D. D. Fagagna,et al. Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation , 2012, Nature Cell Biology.
[6] Gerald C. Chu,et al. Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases , 2012, Cell.
[7] M. Blagosklonny. Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging , 2012, Aging.
[8] Colin S. Gillespie,et al. A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations , 2012, PloS one.
[9] J. Shay,et al. Is telomerase a viable target in cancer? , 2012, Mutation research.
[10] J. Murnane,et al. Telomere dysfunction and chromosome instability. , 2012, Mutation research.
[11] Clara Correia-Melo,et al. Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence , 2012, Nature Communications.
[12] N. LeBrasseur,et al. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders , 2011, Nature.
[13] M. Pagel,et al. Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination , 2011, Aging cell.
[14] C. Harley,et al. The telomerase activator TA‐65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence , 2011, Aging cell.
[15] F. D. D. Fagagna,et al. Never-ageing cellular senescence , 2011, European journal of cancer.
[16] J. DeGregori. Evolved tumor suppression: why are we so good at not getting cancer? , 2011, Cancer research.
[17] C. Maley,et al. Peto's Paradox: evolution's prescription for cancer prevention. , 2011, Trends in ecology & evolution.
[18] M. Bronner,et al. Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation. , 2011, Cancer research.
[19] J. Campisi,et al. Four faces of cellular senescence , 2011, The Journal of cell biology.
[20] L. Chin,et al. Telomere dysfunction induces metabolic and mitochondrial compromise , 2011, Nature.
[21] J. Campisi,et al. DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion , 2011, Journal of Cell Science.
[22] Toru M. Nakamura,et al. Telomeres avoid end detection by severing the checkpoint signal transduction pathway , 2010, Nature.
[23] M. Lynch. Evolution of the mutation rate. , 2010, Trends in genetics : TIG.
[24] L. Lau,et al. The Matricellular Protein CCN1/CYR61 Induces Fibroblast Senescence and Restricts Fibrosis in Cutaneous Wound Healing , 2010, Nature Cell Biology.
[25] T. Lange,et al. Persistent Telomere Damage Induces Bypass of Mitosis and Tetraploidy , 2010, Cell.
[26] P. Edwards. Fusion genes and chromosome translocations in the common epithelial cancers , 2009, The Journal of pathology.
[27] R. DePinho,et al. Telomeres and telomerase in cancer. , 2010, Carcinogenesis.
[28] T. de Lange. How Telomeres Solve the End-Protection Problem , 2009, Science.
[29] Alberto Mantovani,et al. Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. , 2009, Carcinogenesis.
[30] Judith Campisi,et al. Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor , 2008, PLoS biology.
[31] Jonathan Melamed,et al. Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence , 2008, Cell.
[32] P. Hornsby,et al. Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion. , 2007, Cancer research.
[33] Jessie C. Jeyapalan,et al. Accumulation of senescent cells in mitotic tissue of aging primates , 2007, Mechanisms of Ageing and Development.
[34] J. Campisi,et al. Secretion of Vascular Endothelial Growth Factor by Primary Human Fibroblasts at Senescence* , 2006, Journal of Biological Chemistry.
[35] J. Campisi,et al. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation , 2004, Journal of Cell Science.
[36] M. A. Goldman. The role of telomeres and telomerase in cancer. , 2003, Drug discovery today.
[37] R. DePinho,et al. Constitutive telomerase expression promotes mammary carcinomas in aging mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[38] J. Shay,et al. Telomerase and differentiation in multicellular organisms: turn it off, turn it on, and turn it off again. , 2002, Differentiation; research in biological diversity.
[39] J. Campisi,et al. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[40] M. Blasco,et al. Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes , 2001, The EMBO journal.
[41] Lynda Chin,et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice , 2000, Nature.
[42] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[43] J. Shay,et al. A survey of telomerase activity in human cancer. , 1997, European journal of cancer.
[44] C. Harley,et al. Telomeres shorten during ageing of human fibroblasts , 1990, Nature.
[45] P. N. Lee,et al. Cancer and ageing in mice and men. , 1975, British Journal of Cancer.
[46] L. Hayflick,et al. The serial cultivation of human diploid cell strains. , 1961, Experimental cell research.
[47] P. Medawar. UNSOLVED problem of biology. , 1953, The Medical journal of Australia.