论文信息 - Trends in Opioid Toxicity–Related Deaths in the US Before and After the Start of the COVID-19 Pandemic, 2011-2021

Trends in Opioid Toxicity–Related Deaths in the US Before and After the Start of the COVID-19 Pandemic, 2011-2021

Key Points Question What is the societal burden of unintentional opioid-related deaths in the US, and has it changed during the COVID-19 pandemic? Findings In this cross-sectional study of 422 605 unintentional deaths due to opioid toxicity, the years of life lost increased more than 3-fold, from 777 597 to 2 922 497, between 2011 and 2021. By 2021, 1 of every 22 deaths in the US was attributable to unintentional opioid toxicity. Meaning The findings of this study suggest that public health impacts of opioid-related toxicity in the US are broad and have worsened during the pandemic, underscoring the urgent need to support people at risk of substance-related harm, particularly men, younger adults, and adolescents.

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