Levels of lipid peroxidation products and activity of antiradical defense enzymes in blood of patients with Bechterew disease

AIM To study lipid peroxidation (LPO) in Bechterev's disease (BD) treated with antiinflammatory and antioxidant drugs. MATERIAL AND METHODS LPO was estimated in 75 BD patients before medication and during this treatment. 30 healthy volunteers served control. RESULTS Levels of LPO products was high but activity of antioxidant defense enzymes low in BD patients. CONCLUSION Antiinflammatory drugs meloxicam, indometacin and an antioxidant drug triovit depressed LPO activity, improve the patients' condition and results of functional tests.