Dermoscopy analysis of RGB-images based on comparative features

In this paper, we propose an algorithm for color and texture analysis for dermoscopic images of human skin based on Haar wavelets, Local Binary Patterns (LBP) and Histogram Analysis. This approach is a modification of «7-point checklist» clinical method. Thus, that is an “absolute” diagnostic method because one is using only features extracted from tumor’s ROI (Region of Interest), which can be selected manually and/or using a special algorithm. We propose additional features extracted from the same image for comparative analysis of tumor and healthy skin. We used Euclidean distance, Cosine similarity, and Tanimoto coefficient as comparison metrics between color and texture features extracted from tumor’s and healthy skin’s ROI separately. A classifier for separating melanoma images from other tumors has been built by SVM (Support Vector Machine) algorithm. Classification’s errors with and without comparative features between skin and tumor have been analyzed. Significant increase of recognition quality with comparative features has been demonstrated. Moreover, we analyzed two modes (manual and automatic) for ROI selecting on tumor and healthy skin areas. We have reached 91% of sensitivity using comparative features in contrast with 77% of sensitivity using the only “absolute” method. The specificity was the invariable (94%) in both cases.

[1]  David Polsky,et al.  Early diagnosis of cutaneous melanoma: revisiting the ABCD criteria. , 2004, JAMA.

[2]  Rui Hu,et al.  Implementation of the 7-point checklist for melanoma detection on smart handheld devices , 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[3]  A. Marghoob,et al.  The diagnostic performance of expert dermoscopists vs a computer-vision system on small-diameter melanomas. , 2008, Archives of dermatology.

[4]  A. Kopf,et al.  Early detection of malignant melanoma: The role of physician examination and self‐examination of the skin , 1985, CA: a cancer journal for clinicians.

[5]  Randy H. Moss,et al.  Fast and accurate border detection in dermoscopy images using statistical region merging , 2007, SPIE Medical Imaging.

[6]  Anita Mahadevan-Jansen,et al.  Comparison of autofluorescence, diffuse reflectance, and Raman spectroscopy for breast tissue discrimination. , 2008, Journal of biomedical optics.

[7]  D. McLean,et al.  Real-time Raman Spectroscopy for in Vivo Skin Cancer Diagnosis Raman Spectroscopy of Skin Cancer , 2022 .

[8]  C. Berking,et al.  The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study , 2015, The British journal of dermatology.

[9]  B. Thiers,et al.  The CASH (color, architecture, symmetry, and homogeneity) algorithm for dermoscopy , 2008 .

[10]  R. Jain,et al.  Cancer imaging by optical coherence tomography: preclinical progress and clinical potential , 2012, Nature Reviews Cancer.

[11]  Matti Pietikäinen,et al.  Performance evaluation of texture measures with classification based on Kullback discrimination of distributions , 1994, Proceedings of 12th International Conference on Pattern Recognition.

[12]  Haishan Zeng,et al.  Real-Time Raman Spectroscopy for Noninvasive in vivo Skin Analysis and Diagnosis , 2010 .

[13]  P. Boyle,et al.  World Cancer Report 2008 , 2009 .

[14]  G. Argenziano,et al.  Epiluminescence microscopy for the diagnosis of doubtful melanocytic skin lesions. Comparison of the ABCD rule of dermatoscopy and a new 7-point checklist based on pattern analysis. , 1998, Archives of dermatology.