Informing Substitution to Safer Alternatives

The sections in this article are Design for Environment Approaches to Risk Reduction: Identifying and Encouraging the Use of Safer Chemistry Assessment of Safer Chemical Alternatives: Enabling Scientific, Technological, and Commercial Development Informed Substitution Functional Use as an Analytical Construct Defining Safer Chemistry – the DfE Criteria for Safer Chemical Ingredients Continuous Improvement to Advance Green Chemistry Best Practices to Manage Risks in the Absence of Safer Substitutes Life-Cycle Thinking: A Holistic Approach Examples that Illustrate Informed Substitution Informing Real-Time Substitution Decisions: Chemical Alternative Assessment for Pentabromodiphenyl Ether The Partnership The Alternatives Assessment Encouraging Informed Substitution: Safer Product Labeling Program Substituting to Safer Surfactants The Safer Detergents Stewardship Initiative CleanGredients® Developing and Applying Best Practices in the Absence of Safer Substitutes: Isocyanates Best Practices as an Important Risk Management Approach New Developments in Manufacturing Polyurethanes Without Using Isocyanates Safer Manufacture of Diisocyanates Without Using Phosgene Life-Cycle Assessment to Inform Alternatives to Leaded Solder for Electronics Conclusion Disclaimer Keywords: informing substitution; risk reduction; life-cycle; functional use; safer chemicals; green chemistry