Molecular Imaging of Inflammation Using Echocardiography. Advances with the Use of Microbubbles

[1]  Sanjiv S Gambhir,et al.  Earlier detection of breast cancer with ultrasound molecular imaging in a transgenic mouse model. , 2013, Cancer research.

[2]  Michael B Lawrence,et al.  Ultrasound-based molecular imaging and specific gene delivery to mesenteric vasculature by endothelial adhesion molecule targeted microbubbles in a mouse model of Crohn's disease. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[3]  A. Klibanov,et al.  Ultrasound-mediated vascular gene transfection by cavitation of endothelial-targeted cationic microbubbles. , 2012, JACC. Cardiovascular imaging.

[4]  M. Arditi,et al.  Effects of acoustic radiation force on the binding efficiency of BR55, a VEGFR2-specific ultrasound contrast agent. , 2012, Ultrasound in medicine & biology.

[5]  S. Homma,et al.  Effect of surface architecture on in vivo ultrasound contrast persistence of targeted size-selected microbubbles. , 2012, Ultrasound in medicine & biology.

[6]  Shunichi Homma,et al.  Polyplex-microbubble hybrids for ultrasound-guided plasmid DNA delivery to solid tumors. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[7]  J. Lindner,et al.  Dysregulated Selectin Expression and Monocyte Recruitment During Ischemia-Related Vascular Remodeling in Diabetes Mellitus , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[8]  Kumar Sharma,et al.  Ultrasound Molecular Imaging of Tumor Angiogenesis With an Integrin Targeted Microbubble Contrast Agent , 2011, Investigative radiology.

[9]  J. Willmann,et al.  Tumor angiogenic marker expression levels during tumor growth: longitudinal assessment with molecularly targeted microbubbles and US imaging. , 2011, Radiology.

[10]  A. H. Myrset,et al.  Design and characterization of targeted ultrasound microbubbles for diagnostic use. , 2011, Ultrasound in medicine & biology.

[11]  V. Herrera,et al.  Molecular Imaging of Vasa Vasorum Neovascularization via DEspR-targeted Contrast-enhanced Ultrasound Micro-imaging in Transgenic Atherosclerosis Rat Model , 2011, Molecular Imaging and Biology.

[12]  Isabelle Tardy,et al.  BR55: A Lipopeptide-Based VEGFR2-Targeted Ultrasound Contrast Agent for Molecular Imaging of Angiogenesis , 2010, Investigative radiology.

[13]  Katherine W Ferrara,et al.  Lipid-shelled vehicles: engineering for ultrasound molecular imaging and drug delivery. , 2009, Accounts of chemical research.

[14]  K. Vandegriff,et al.  Hemospan: design principles for a new class of oxygen therapeutic. , 2009, Artificial organs.

[15]  Hairong Zheng,et al.  Dynamic microPET imaging of ultrasound contrast agents and lipid delivery. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[16]  Sanjiv S Gambhir,et al.  Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice. , 2008, Radiology.

[17]  S. Kaul,et al.  Molecular Imaging of Endothelial Vascular Cell Adhesion Molecule-1 Expression and Inflammatory Cell Recruitment During Vasculogenesis and Ischemia-Mediated Arteriogenesis , 2008, Circulation.

[18]  L. Frizzell,et al.  American Institute of Ultrasound in Medicine Consensus Report on Potential Bioeffects of Diagnostic Ultrasound , 2008, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[19]  Junru Wu,et al.  Bioeffects Considerations for Diagnostic Ultrasound Contrast Agents , 2008, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[20]  S. Delorme,et al.  Pharmacodynamics of Streptavidin-Coated Cyanoacrylate Microbubbles Designed for Molecular Ultrasound Imaging , 2008, Investigative radiology.

[21]  A. Siegbahn,et al.  Prasugrel achieves greater and faster P2Y12receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. , 2007, European heart journal.

[22]  John C Gore,et al.  Molecular Imaging of Vascular Endothelial Growth Factor Receptor 2 Expression Using Targeted Contrast‐Enhanced High‐Frequency Ultrasonography , 2007, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[23]  Sanjiv S Gambhir,et al.  microPET-Based Biodistribution of Quantum Dots in Living Mice , 2007, Journal of Nuclear Medicine.

[24]  D. Cosgrove,et al.  WFUMB Safety Symposium on Ultrasound Contrast Agents: clinical applications and safety concerns. , 2007, Ultrasound in medicine & biology.

[25]  Rolf A. Brekken,et al.  Monitoring Response to Anticancer Therapy by Targeting Microbubbles to Tumor Vasculature , 2007, Clinical Cancer Research.

[26]  D. Larkman,et al.  Detection of vascular expression of E-selectin in vivo with MR imaging. , 2006, Radiology.

[27]  Jonathan R Lindner,et al.  Effect of Microbubble Ligation to Cells on Ultrasound Signal Enhancement: Implications for Targeted Imaging , 2006, Investigative radiology.

[28]  B. Wang,et al.  Prolonging the ultrasound signal enhancement from thrombi using targeted microbubbles based on sulfur-hexafluoride-filled gas. , 2006, Academic radiology.

[29]  T. Skotland,et al.  Disposition of perfluorobutane in rats after intravenous injection of Sonazoid. , 2006, Ultrasound in medicine & biology.

[30]  Antony K. Chen,et al.  Superparamagnetic Iron Oxide Nanoparticle Probes for Molecular Imaging , 2006, Annals of Biomedical Engineering.

[31]  B. Goldberg,et al.  Contrast‐Enhanced Sonographic Imaging of Lymphatic Channels and Sentinel Lymph Nodes , 2005, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[32]  P. Phillips,et al.  Contrast–agent detection and quantification , 2004, European radiology.

[33]  P. Tipping,et al.  J Am Soc Nephrol 14: 1785–1793, 2003 Intrinsic Renal Cells Are the Major Source of Tumor Necrosis Factor Contributing to Renal Injury in Murine Crescentic , 2022 .

[34]  Douglas L Mann,et al.  Inflammatory mediators and the failing heart: past, present, and the foreseeable future. , 2002, Circulation research.

[35]  Ji Song,et al.  Influence of microbubble shell properties on ultrasound signal: Implications for low-power perfusion imaging. , 2002, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[36]  J. Lowe Glycosylation in the control of selectin counter‐receptor structure and function , 2002, Immunological reviews.

[37]  D. Haskard,et al.  Clinical overview of leukocyte adhesion and migration: where are we now? , 2002, Seminars in immunology.

[38]  S. Kaul,et al.  Myocardial and microcirculatory kinetics of BR14, a novel third-generation intravenous ultrasound contrast agent. , 2002, Journal of the American College of Cardiology.

[39]  Alexander L. Klibanov,et al.  Ultrasound Contrast Agents: Development of the Field and Current Status , 2002 .

[40]  F. Jamar,et al.  Scintigraphy using a technetium 99m-labelled anti-E-selectin Fab fragment in rheumatoid arthritis. , 2002, Rheumatology.

[41]  K. Ley,et al.  Ultrasound Assessment of Inflammation and Renal Tissue Injury With Microbubbles Targeted to P-Selectin , 2001, Circulation.

[42]  R M Lang,et al.  Combined Assessment of Myocardial Perfusion and Regional Left Ventricular Function by Analysis of Contrast-Enhanced Power Modulation Images , 2001, Circulation.

[43]  D. Granger,et al.  Adhesion molecules and their role in vascular disease. , 2001, American journal of hypertension.

[44]  G. Kansas Selectins and Their Ligands in Inflammation , 2001 .

[45]  P. Dayton,et al.  Mechanisms of contrast agent destruction , 2001, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[46]  Klaus Ley,et al.  Physiology of Inflammation , 2001, Methods in Physiology Series.

[47]  S. Kaul,et al.  Noninvasive Ultrasound Imaging of Inflammation Using Microbubbles Targeted to Activated Leukocytes , 2000, Circulation.

[48]  M. Cybulsky,et al.  The NF-kappa B signal transduction pathway in aortic endothelial cells is primed for activation in regions predisposed to atherosclerotic lesion formation. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[49]  S. Kaul,et al.  Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. , 2000, Circulation.

[50]  B. Horne,et al.  Soluble VCAM-1 and E-Selectin, but Not ICAM-1 Discriminate Endothelial Injury in Patients with Documented Coronary Artery Disease , 2000, Cardiology.

[51]  L. Lindbom,et al.  Direct observations in vivo on the role of endothelial selectins and alpha(4) integrin in cytokine-induced leukocyte-endothelium interactions in the mouse aorta. , 2000, Circulation research.

[52]  J. Llull,et al.  Human pharmacokinetics and safety evaluation of SonoVue, a new contrast agent for ultrasound imaging. , 2000, Investigative radiology.

[53]  N. Pandian,et al.  Enhanced visualization of intravascular and left atrial appendage thrombus with the use of a thrombus-targeting ultrasonographic contrast agent (MRX-408A1): In vivo experimental echocardiographic studies. , 1999, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[54]  F. Luscinskas,et al.  Acquisition of Selectin Binding and Peripheral Homing Properties by CD4+ and CD8+ T Cells , 1999, The Journal of experimental medicine.

[55]  H. Dittrich,et al.  Tissue Distribution of125 l-LabeIed Albumin in Rats, and Whole Blood and Exhaled Elimination Kinetics of Octafluoropropane in Anesthetized Canines, Following Intravenous Administration of Optison® (FS069) , 1999 .

[56]  R. Ross,et al.  Atherosclerosis is an inflammatory disease. , 1998, American heart journal.

[57]  H. Dittrich,et al.  Physiologically based pharmacokinetic model for fluorocarbon elimination after the administration of an octafluoropropane‐albumin microsphere sonographic contrast agent. , 1999, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[58]  J. Brain,et al.  Pulmonary intravascular macrophages: their contribution to the mononuclear phagocyte system in 13 species. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[59]  K W Ferrara,et al.  Direct video-microscopic observation of the dynamic effects of medical ultrasound on ultrasound contrast microspheres. , 1998, Investigative radiology.

[60]  A R Jayaweera,et al.  Albumin microbubble persistence during myocardial contrast echocardiography is associated with microvascular endothelial glycocalyx damage. , 1998, Circulation.

[61]  T C Skalak,et al.  Direct In Vivo Visualization of Intravascular Destruction of Microbubbles by Ultrasound and Its Local Effects on Tissue. , 1998, Circulation.

[62]  Simon C Watkins,et al.  Microbubbles targeted to intercellular adhesion molecule-1 bind to activated coronary artery endothelial cells. , 1998, Circulation.

[63]  P. Chapman,et al.  Visualising E-selectin in the detection and evaluation of inflammatory bowel disease , 1998, Gut.

[64]  M. Cremonesi,et al.  Biochemical modifications of avidin improve pharmacokinetics and biodistribution, and reduce immunogenicity. , 1998, British Journal of Cancer.

[65]  A. Kabalnov,et al.  Dissolution of multicomponent microbubbles in the bloodstream: 1. Theory. , 1998, Ultrasound in medicine & biology.

[66]  S Otto,et al.  Dissolution of multicomponent microbubbles in the bloodstream: 2. Experiment. , 1998, Ultrasound in medicine & biology.

[67]  M. Kaps,et al.  The Influence of Different Gases on Acoustic Properties of a Spherosome‐Based Ultrasound Contrast Agent (BY963) , 1998, Journal of neuroimaging : official journal of the American Society of Neuroimaging.

[68]  A. Perkins,et al.  Human biodistribution of an ultrasound contrast agent (Quantison) by radiolabelling and gamma scintigraphy. , 1997, The British journal of radiology.

[69]  J. Schaper,et al.  Upregulation of cell adhesion molecules and the presence of low grade inflammation in human chronic heart failure. , 1997, European heart journal.

[70]  A. Scheffold,et al.  P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues , 1997, Nature.

[71]  M. Allen,et al.  VCAM-1 and E-selectin expression during cytomegalovirus infection in post-transplant myocardial biopsies. , 1996, Clinical transplantation.

[72]  Y. Yazaki,et al.  EXPRESSION OF VASCULAR CELL ADHESION MOLECULE‐1 IN MURINE HEARTS WITH ACUTE MYOCARDITIS CAUSED BY COXSACKIEVIRUS B3 , 1996, The Journal of pathology.

[73]  M. Labow,et al.  Heterogeneity of expression of E- and P-selectins in vivo. , 1996, Circulation research.

[74]  T. Hamblin,et al.  Response of B-cell lymphoma to a combination of bispecific antibodies and saporin. , 1996, Leukemia research.

[75]  H. Schultheiss,et al.  Immunohistological evidence for a chronic intramyocardial inflammatory process in dilated cardiomyopathy. , 1996, Heart.

[76]  S. Renowden,et al.  Pictorial review: MR imaging of neuronal migration anomalies. , 1996, Clinical Radiology.

[77]  T. Maniatis,et al.  Transcriptional regulation of endothelial cell adhesion molecules : NF-icB and cytokine-inducible enhancers , 2004 .

[78]  T. Martino,et al.  Enteroviral Myocarditis and Dilated Cardiomyopathy: a Review of Clinical and Experimental Studies , 1995 .

[79]  H. Rotbart Human enterovirus infections. , 1995 .

[80]  R. Swerlick,et al.  Alternatively processed human E-selectin transcripts linked to chronic expression of E-selectin in vivo. , 1994, Journal of immunology.

[81]  Sanjiv Kaul,et al.  Quantification of Myocardial Perfusion With Myocardial Contrast Echocardiography During Left Atrial Injection of Contrast: Implications for Venous Injection , 1994, Circulation.

[82]  A. Weyman,et al.  Effect of static pressure on the disappearance rate of specific echocardiographic contrast agents. , 1994, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[83]  J. Ostensen,et al.  Albunex--a new ultrasound contrast agent. Effects on hemodynamics, contrast, and biodistribution in different species. , 1994, Investigative radiology.

[84]  S. Kaul,et al.  In vivo myocardial kinetics of air-filled albumin microbubbles during myocardial contrast echocardiography. Comparison with radiolabeled red blood cells. , 1994, Circulation research.

[85]  T. Kuijpers,et al.  Cytokine-activated endothelial cells internalize E-selectin into a lysosomal compartment of vesiculotubular shape. A tubulin-driven process. , 1994, Journal of immunology.

[86]  T. Gjøen,et al.  Biodistributions of air-filled albumin microspheres in rats and pigs. , 1994, The Biochemical journal.

[87]  M. Bevilacqua,et al.  Endothelial-leukocyte adhesion molecules in human disease. , 1994, Annual review of medicine.

[88]  D. Reichenbach,et al.  E‐Selectin Expression in Human Cardiac Grafts With Cellular Rejection , 1993, Circulation.

[89]  Nico de Jong,et al.  Acoustic properties of ultrasound contrast agents , 1993 .

[90]  Y. Yazaki,et al.  Expression of intercellular adhesion molecule-1 in murine hearts with acute myocarditis caused by coxsackievirus B3. , 1993, The Journal of clinical investigation.

[91]  Sverre Holm,et al.  Albunex-a new ultrasound contrast agent , 1993 .

[92]  T. V. Gopal,et al.  Soluble E-selectin is found in supernatants of activated endothelial cells and is elevated in the serum of patients with septic shock. , 1993, Journal of immunology.

[93]  J. Ostensen,et al.  Intravenous injection of Albunex microspheres causes thromboxane mediated pulmonary hypertension in pigs, but not in monkeys or rabbits. , 1992, Acta physiologica Scandinavica.

[94]  N de Jong,et al.  Absorption and scatter of encapsulated gas filled microspheres: theoretical considerations and some measurements. , 1992, Ultrasonics.

[95]  Timothy A. Springer,et al.  Adhesion receptors of the immune system , 1990, Nature.

[96]  G. Winkler Review of the significance of pulmonary intravascular macrophages with respect to animal species and age. , 1989, Experimental cell biology.

[97]  N. Green,et al.  The accessibility of protein-bound dinitrophenyl groups to univalent fragments of anti-dinitrophenyl antibody. , 1976, The Biochemical journal.