Allosteric coupling from G protein to the agonist binding pocket in GPCRs
暂无分享,去创建一个
S. Rasmussen | Brian T DeVree | E. Pardon | J. Steyaert | R. Sunahara | B. Kobilka | J. Fung | A. Manglik | A. Kuszak | M. Masureel | Gisselle A. Vélez-Ruiz | Y. Du | R. Matt | Jacob P. Mahoney | E. Edwald | Yang Du
[1] Stephen M. Husbands,et al. Structural insights into μ-opioid receptor activation , 2015, Nature.
[2] B. Krumm,et al. Structural prerequisites for G-protein activation by the neurotensin receptor , 2015, Nature Communications.
[3] Vadim Cherezov,et al. Allosteric sodium in class A GPCR signaling. , 2014, Trends in biochemical sciences.
[4] J. Wess,et al. Activation and allosteric modulation of a muscarinic acetylcholine receptor , 2013, Nature.
[5] K. Garcia,et al. Adrenaline-activated structure of the β2-adrenoceptor stabilized by an engineered nanobody , 2013, Nature.
[6] Jonathan R. Tomshine,et al. Conformational biosensors reveal GPCR signalling from endosomes , 2013, Nature.
[7] L. Pardo,et al. Crystal structure of the μ-opioid receptor bound to a morphinan antagonist , 2012, Nature.
[8] A. Kruse,et al. Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist , 2011, Nature.
[9] Virgil L. Woods,et al. Conformational changes in the G protein Gs induced by the β2 adrenergic receptor , 2011, Nature.
[10] Tong Liu,et al. Structural flexibility of the Gαs α-helical domain in the β2-adrenoceptor Gs complex , 2011, Proceedings of the National Academy of Sciences.
[11] Albert C. Pan,et al. Pathway and mechanism of drug binding to G-protein-coupled receptors , 2011, Proceedings of the National Academy of Sciences.
[12] S. Rasmussen,et al. Crystal Structure of the β2Adrenergic Receptor-Gs protein complex , 2011, Nature.
[13] Christopher G. Tate,et al. The structural basis for agonist and partial agonist action on a β1-adrenergic receptor , 2010, Nature.
[14] Cheng Zhang,et al. Structure and Function of an Irreversible Agonist-β2 Adrenoceptor complex , 2010, Nature.
[15] S. Rasmussen,et al. Structure of a nanobody-stabilized active state of the β2 adrenoceptor , 2010, Nature.
[16] L. Pardo,et al. Ligand-specific regulation of the extracellular surface of a G protein coupled receptor , 2009, Nature.
[17] S. Rasmussen,et al. The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex , 2009, Proceedings of the National Academy of Sciences.
[18] Richard N. Zare,et al. A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein , 2007, Proceedings of the National Academy of Sciences.
[19] D. Bylund,et al. A robust GTP-induced shift in α2-adrenoceptor agonist affinity in tissue sections from rat brain , 2001, Journal of Neuroscience Methods.
[20] T. Kenakin,et al. The cubic ternary complex receptor-occupancy model. III. resurrecting efficacy. , 1996, Journal of theoretical biology.
[21] P. Morgan,et al. The Cubic Ternary Complex ReceptorOccupancy Model I. Model Description , 1996 .
[22] A. Gilman,et al. Purification of Recombinant G Proteins from Sf9 Cells by Hexahistidine Tagging of Associated Subunits , 1995, The Journal of Biological Chemistry.
[23] R. Lefkowitz,et al. A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model. , 1993, The Journal of biological chemistry.
[24] J. Linden,et al. Indirect effect of guanine nucleotides on antagonist binding to A1 adenosine receptors: occupation of cryptic binding sites by endogenous vesicular adenosine. , 1992, Molecular pharmacology.
[25] B. Cox,et al. Multiple agonist-affinity states of opioid receptors: regulation of binding by guanyl nucleotides in guinea pig cortical, NG108-15, and 7315c cell membranes. , 1988, Molecular pharmacology.
[26] D. Mccormick. Sequence the Human Genome , 1986, Bio/Technology.
[27] R. Lefkowitz,et al. Reciprocal modulation of agonist and antagonist binding to muscarinic cholinergic receptor by guanine nucleotide. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[28] Y. Giudicelli,et al. Catecholamine binding to the α-adrenergic receptors of hamster adipocytes evidence that guanine nucleotides regulate this binding to the α2-receptor subtype , 1982 .
[29] R. Lefkowitz,et al. A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor. , 1980, The Journal of biological chemistry.
[30] M. Maguire,et al. Relationship between the beta-adrenergic receptor and adenylate cyclase. , 1977, The Journal of biological chemistry.
[31] R. Lefkowitz,et al. Catecholamine binding to the beta-adrenergic receptor. , 1977, Proceedings of the National Academy of Sciences of the United States of America.
[32] M. Maguire,et al. An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor. , 1976, Molecular pharmacology.
[33] H. Horiuchi. Seven-transmembrane receptors , 2015 .
[34] Robert,et al. A Mutation-induced Activated State of the ,&-Adrenergic Receptor EXTENDING THE TERNARY COMPLEX MODEL* , 2001 .
[35] H. Kikkawa,et al. The role of the seventh transmembrane region in high affinity binding of a beta 2-selective agonist TA-2005. , 1998, Molecular pharmacology.
[36] S R Sprang,et al. G protein mechanisms: insights from structural analysis. , 1997, Annual review of biochemistry.