Split face study on the cutaneous tensile effect of 2‐dimethylaminoethanol (deanol) gel

Background/aims: Beyond subjective assessments, the effect of skin tensors is difficult to assess. The present 2‐phase randomized double‐blind split face study was designed to compare the effect of a gel containing 3% 2‐dimethylaminoethanol (deanol, DMAE) with the same formulation without DMAE.

[1]  R. Buchli,et al.  Human skin fibroblasts express m2, m4, and m5 subtypes of muscarinic acetylcholine receptors , 1999, Journal of cellular biochemistry.

[2]  T. X. Lee,et al.  Activation of keratinocyte nicotinic cholinergic receptors stimulates calcium influx and enhances cell differentiation. , 1996, The Journal of investigative dermatology.

[3]  V. Rogiers,et al.  EEMCO Guidance for the in vivo Assessment of Skin Greasiness , 2000, Skin Pharmacology and Physiology.

[4]  J. Mansour,et al.  Age-dependent changes in the shear wave propagation through human skin , 1989, Experimental Gerontology.

[5]  S. Grando.  Biological functions of keratinocyte cholinergic receptors. , 1997, The journal of investigative dermatology. Symposium proceedings.

[6]  C. Kirkpatrick,et al.  Non-neuronal acetylcholine, a signalling molecule synthezised by surface cells of rat and man , 1997, Naunyn-Schmiedeberg's Archives of Pharmacology.

[7]  C. Piérard-Franchimont,et al.  Influence of Body Posture and Gravitational Forces on Shear Wave Propagation in the Skin , 2001, Dermatology.

[8]  G. Piérard,et al.  Microanatomy of the dermis in relation to relaxed skin tension lines and Langer's lines. , 1987, The American Journal of dermatopathology.

[9]  R O Potts,et al.  The dynamic mechanical properties of human skin in vivo. , 1983, Journal of biomechanics.

[10]  J. Fissette,et al.  Skin barrier repair after contact burns. electrometric evaluation using the passive sustainable hydration test , 1999 .

[11]  I. Fumal,et al.  Sensitive skin at menopause; dew point and electrometric properties of the stratum corneum. , 1998, Maturitas.

[12]  A. Vexler,et al.  Evaluation of skin viscoelasticity and anisotropy by measurement of speed of shear wave propagation with viscoelasticity skin analyzer. , 1999, The Journal of investigative dermatology.

[13]  D. Jenden,et al.  Dimethylaminoethanol (deanol) metabolism in rat brain and its effect on acetylcholine synthesis. , 1979, The Journal of pharmacology and experimental therapeutics.

[14]  H Alexander,et al.  Accounting for natural tension in the mechanical testing of human skin. , 1977, The Journal of investigative dermatology.

[15]  A F BORGES,et al.  Relaxed skin tension lines, Z-plasties on scars, and fusiform excision of lesions. , 1962, British journal of plastic surgery.

[16]  R O Potts,et al.  Changes with age in the moisture content of human skin. , 1985, The Journal of investigative dermatology.

[17]  G. Piérard,et al.  Age- and body mass index-related changes in cutaneous shear wave velocity , 2001, Experimental Gerontology.

[18]  A F Borges,et al.  Relaxed skin tension lines (RSTL) versus other skin lines. , 1984, Plastic and reconstructive surgery.

[19]  R. Buchli,et al.  Identification and mapping of keratinocyte muscarinic acetylcholine receptor subtypes in human epidermis. , 1998, The Journal of investigative dermatology.

[20]  E. Albuquerque,et al.  A nicotinic acetylcholine receptor regulating cell adhesion and motility is expressed in human keratinocytes. , 1995, The Journal of investigative dermatology.

[21]  D. Haubrich,et al.  Deanol Affects Choline Metabolism in Peripheral Tissues of Mice , 1981, Journal of neurochemistry.