Assessment of the extent of microcalcifications to predict the size of a ductal carcinoma in situ: comparison between tomosynthesis and conventional mammography.

OBJECTIVES The objective was to determine if digital tomosynthesis of the breast (DBT) assesses the extension of ductal carcinoma in situ (DCIS) with higher precision than mammography (MG). MATERIAL AND METHODS The local ethics committee approved this retrospective study including 26 patients with DCIS, which were rated by three radiologists. Statistics were performed using intraclass correlation (ICC) for interreader agreement and the Pearson correlation for correlation of MG and DBT. Standard of reference was the histologic extension. RESULTS The ICC was excellent. Correlation between MG and histology was 0.879 (P<.01) and for DBT and histology was 0.914 (P<.01). CONCLUSION DBT provides a slightly better estimation of the size of a DCIS than MG.

[1]  George Hermann,et al.  Mammographic Appearance of Nonpalpable Breast Cancer Reflects Pathologic Characteristics , 2002, Annals of surgery.

[2]  P. Hermanek,et al.  The pathologist and the residual tumor (R) classification. , 1994, Pathology, research and practice.

[3]  S. Astley,et al.  Digital breast tomosynthesis at screening assessment: are two views always necessary? , 2015, The British journal of radiology.

[4]  A. Beckett,et al.  AKUFO AND IBARAPA. , 1965, Lancet.

[5]  J M Bland,et al.  Statistical methods for assessing agreement between two methods of clinical measurement , 1986 .

[6]  David Gur,et al.  Time to diagnosis and performance levels during repeat interpretations of digital breast tomosynthesis: preliminary observations. , 2010, Academic radiology.

[7]  T. Yokoi,et al.  Extensive intraductal component (EIC) and estrogen receptor (ER) status in breast cancer , 1998, Pathology international (Print).

[8]  J. Peterse,et al.  Breast-conserving treatment with or without radiotherapy in ductal carcinoma-in-situ: ten-year results of European Organisation for Research and Treatment of Cancer randomized phase III trial 10853--a study by the EORTC Breast Cancer Cooperative Group and EORTC Radiotherapy Group. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[9]  Brittany Lapin,et al.  Repeat surgery after breast conservation for the treatment of stage 0 to II breast carcinoma: a report from the National Cancer Data Base, 2004-2010. , 2014, JAMA surgery.

[10]  Per Skaane,et al.  Overview of the evidence on digital breast tomosynthesis in breast cancer detection. , 2013, Breast.

[11]  D. Cicchetti.  Guidelines, Criteria, and Rules of Thumb for Evaluating Normed and Standardized Assessment Instruments in Psychology. , 1994 .

[12]  S. Pinder,et al.  Ductal carcinoma in situ of the breast: correlation between mammographic and pathologic findings. , 1994, AJR. American journal of roentgenology.

[13]  M. Morrow,et al.  Is There a Low-Grade Precursor Pathway in Breast Cancer? , 2012, Annals of Surgical Oncology.

[14]  Kornelia Polyak,et al.  Ductal Carcinoma in Situ of the Breast , 2004, Strahlentherapie und Onkologie.

[15]  Andriy I. Bandos,et al.  Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. , 2013, Radiology.

[16]  S. Ciatto,et al.  Integration of 3D digital mammography with tomosynthesis for population breast-cancer screening (STORM): a prospective comparison study. , 2013, The Lancet. Oncology.

[17]  S. Meterissian,et al.  Value of pre-operative breast MRI for the size assessment of ductal carcinoma in situ. , 2016, The British journal of radiology.

[18]  H. Thornton,et al.  Ductal carcinoma-in-situ of the breast , 1992, The Lancet.

[19]  N Houssami,et al.  Application of breast tomosynthesis in screening: incremental effect on mammography acquisition and reading time. , 2012, The British journal of radiology.

[20]  L. Koppert,et al.  Benefits of preoperative MRI in breast cancer surgery studied in a large population‐based cancer registry , 2015, The British journal of surgery.

[21]  J. Peterse,et al.  Breast-conserving treatment with or without radiotherapy for ductal carcinoma in situ (DCIS): ten-year results of European Organisation for Research and Treatment of Cancer (EORTC) randomized phase III trial 10853 , 2006 .

[22]  D. Cicchetti,et al.  Developing criteria for establishing interrater reliability of specific items: applications to assessment of adaptive behavior. , 1981, American journal of mental deficiency.