A volumetric CMUT-based ultrasound imaging system simulator with integrated reception and μ-beamforming electronics models

In modern ultrasound imaging devices, two-dimensional probes and electronic scanning allow volumetric imaging of anatomical structures. When dealing with the design of such complex 3-D ultrasound (US) systems, as the number of transducers and channels dramatically increases, new challenges concerning the integration of electronics and the implementation of smart micro-beamforming strategies arise. Hence, the possibility to predict the behavior of the whole system is mandatory. In this paper, we propose and describe an advanced simulation tool for ultrasound system modeling and simulation, which conjugates the US propagation and scattering, signal transduction, electronic signal conditioning, and beamforming in a single environment. In particular, we present the architecture and model of an existing 16-channel integrated receiver, which includes an amplification and micro-beamforming stage, and validate it by comparison with circuit simulations. The developed model is then used in conjunction with the transducer and US field models to perform a system simulation, aimed at estimating the performance of an example 3-D US imaging system that uses a capacitive micromachined ultrasonic transducer (CMUT) 2-D phased-array coupled to the modeled reception front-end. Results of point spread function (PSF) calculations, as well as synthetic imaging of a virtual phantom, show that this tool is actually able to model the complete US image reconstruction process, and that it could be used to quickly provide valuable system-level feedback for an optimized tuning of electronic design parameters.

[1]  J. Jensen,et al.  Calculation of pressure fields from arbitrarily shaped, apodized, and excited ultrasound transducers , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  G. Tupholme Generation of acoustic pulses by baffled plane pistons , 1969 .

[3]  Jørgen Arendt Jensen,et al.  Computer Phantoms for Simulating Ultrasound B-Mode and CFM Images , 1997 .

[4]  A. Savoia,et al.  Performance optimization of a high frequency CMUT probe for medical imaging , 2011, 2011 IEEE International Ultrasonics Symposium.

[5]  K. Boone,et al.  Effect of skin impedance on image quality and variability in electrical impedance tomography: a model study , 1996, Medical and Biological Engineering and Computing.

[6]  W. P. Mason Electromechanical transducers and wave filters , 1942 .

[7]  O. Oralkan,et al.  Volumetric ultrasound imaging using 2-D CMUT arrays , 2003, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[8]  S.W. Smith,et al.  High-speed ultrasound volumetric imaging system. I. Transducer design and beam steering , 1991, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[9]  Eberhard Brunner,et al.  Ultrasound System Considerations and their Impact on Front-End Components , 2002 .

[10]  P. Stepanishen The Time‐Dependent Force and Radiation Impedance on a Piston in a Rigid Infinite Planar Baffle , 1971 .

[11]  T. Halvorsrod,et al.  A low-power method adding continuous variable gain to amplifiers , 2005, 2005 IEEE International Symposium on Circuits and Systems.

[12]  N de Jong,et al.  Design of a micro-beamformer for a 2D piezoelectric ultrasound transducer , 2009, 2009 IEEE International Ultrasonics Symposium.

[13]  T. Ytterdal,et al.  SCREAM - A discrete time /spl mu/beamformer for CMUT arrays - behavioral simulations using systemc , 2005, IEEE Ultrasonics Symposium, 2005..

[14]  Shinichi Hashimoto,et al.  A two-dimensional array probe that has a huge number of active channels , 2003, IEEE Symposium on Ultrasonics, 2003.

[15]  Nico de Jong,et al.  Front-end receiver electronics for a matrix transducer for 3-D transesophageal echocardiography , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[16]  Donal B. Downey,et al.  Three-dimensional ultrasound imaging , 1995, Medical Imaging.

[17]  Omer Oralkan,et al.  Capacitive micromachined ultrasonic transducers for medical imaging and therapy , 2011, Journal of micromechanics and microengineering : structures, devices, and systems.

[18]  S. Holm Ultrasim-a toolbox for ultrasound field simulation , 2012 .

[19]  B. Savord,et al.  Fully sampled matrix transducer for real time 3D ultrasonic imaging , 2003, IEEE Symposium on Ultrasonics, 2003.

[20]  B.T. Khuri-Yakub,et al.  Analytically calculating membrane displacement and the equivalent circuit model of a circular CMUT cell , 2008, 2008 IEEE Ultrasonics Symposium.

[21]  M. Frijlink,et al.  Abersim: A simulation program for 3D nonlinear acoustic wave propagation for arbitrary pulses and arbitrary transducer geometries , 2008, 2008 IEEE Ultrasonics Symposium.

[22]  Graham M. Treece,et al.  Three-dimensional ultrasound imaging , 2010, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[23]  Butrus T. Khuri-Yakub,et al.  Capacitive Micromachined Ultrasonic Transducers: Theory and Technology , 2003 .

[24]  A. S. Savoia,et al.  A CMUT probe for medical ultrasonography: from microfabrication to system integration , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[25]  J. Arendt Paper presented at the 10th Nordic-Baltic Conference on Biomedical Imaging: Field: A Program for Simulating Ultrasound Systems , 1996 .

[26]  Alessandro Stuart Savoia,et al.  An ultrasound system simulation tool for advanced front-end electronics design , 2012, 2012 IEEE International Ultrasonics Symposium.

[27]  Olivier Basset,et al.  CREANUIS: a non-linear radiofrequency ultrasound image simulator. , 2013, Ultrasound in medicine & biology.

[28]  Seunghun Lee,et al.  Design and test of a fully controllable 64×128 2-D CMUT array integrated with reconfigurable frontend ASICs for volumetric ultrasound imaging , 2012, 2012 IEEE International Ultrasonics Symposium.